IL55253A - Benzimidazole-2-methanol and benzimidazole-2-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Benzimidazole-2-methanol and benzimidazole-2-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL55253A
IL55253A IL55253A IL5525378A IL55253A IL 55253 A IL55253 A IL 55253A IL 55253 A IL55253 A IL 55253A IL 5525378 A IL5525378 A IL 5525378A IL 55253 A IL55253 A IL 55253A
Authority
IL
Israel
Prior art keywords
benzimidazole
methanol
preparation
carboxylic acid
pharmaceutical compositions
Prior art date
Application number
IL55253A
Other languages
English (en)
Other versions
IL55253A0 (en
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU77CI1761A external-priority patent/HU180700B/hu
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL55253A0 publication Critical patent/IL55253A0/xx
Publication of IL55253A publication Critical patent/IL55253A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/12—Radicals substituted by oxygen atoms
IL55253A 1977-08-01 1978-07-31 Benzimidazole-2-methanol and benzimidazole-2-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them IL55253A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU77CI1761A HU180700B (en) 1976-08-27 1977-08-01 Process for producing acylized benzimidasole derivatives
CH209478 1978-02-27

Publications (2)

Publication Number Publication Date
IL55253A0 IL55253A0 (en) 1978-09-29
IL55253A true IL55253A (en) 1982-04-30

Family

ID=25689497

Family Applications (1)

Application Number Title Priority Date Filing Date
IL55253A IL55253A (en) 1977-08-01 1978-07-31 Benzimidazole-2-methanol and benzimidazole-2-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them

Country Status (19)

Country Link
US (1) US4323688A (es)
EP (1) EP0000574B1 (es)
JP (1) JPS5427565A (es)
AR (4) AR227125A1 (es)
AT (1) AT364830B (es)
AU (1) AU523324B2 (es)
CA (1) CA1109072A (es)
DD (1) DD138318A5 (es)
DE (1) DE2861987D1 (es)
DK (1) DK339578A (es)
ES (1) ES472208A1 (es)
FI (1) FI68231C (es)
GR (1) GR77614B (es)
IE (1) IE47285B1 (es)
IL (1) IL55253A (es)
NO (1) NO150082C (es)
NZ (1) NZ188006A (es)
PL (1) PL208772A1 (es)
PT (1) PT68365A (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2861987D1 (en) * 1977-08-01 1982-09-30 Ciba Geigy Ag Benzimidazole-2 derivatives, their preparation and their use for the preparation of medicaments
US4322431A (en) * 1979-02-09 1982-03-30 Ciba-Geigy Corporation Pharmaceutical preparations containing benzimidazole 2-derivatives
US4368201A (en) * 1981-07-20 1983-01-11 Usv Pharmaceutical Corporation Tetrahydronaphthoxazoles

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB243766A (en) * 1924-12-01 1926-07-29 Bayer Ag Process for the manufacture of benzimidazoles
US2053822A (en) * 1933-12-15 1936-09-08 Soc Of Chemical Ind Alkylated imidazoles of high molecular weight and process of making same
GB766749A (en) 1954-01-11 1957-01-23 Aschaffenburger Zellstoffwerke Benzimidazole cobalamines and process for their preparation and separation
US2876233A (en) * 1956-10-29 1959-03-03 Gruenenthal Chemie 1-(p-halobenzyl)-2-methyl benzimidazoles and salts
CH356460A (de) * 1956-10-30 1961-08-31 Gruenenthal Chemie Verfahren zur Herstellung von neuen Derivaten des Benzimidazols
CH356461A (de) * 1956-10-30 1961-08-31 Gruenenthal Chemie Verfahren zur Herstellung von neuen Derivaten des Benzimidazols
CH362411A (de) * 1956-10-30 1962-06-15 Gruenenthal Chemie Verfahren zur Herstellung von neuen Derivaten des Benzimidazols
US3325271A (en) * 1963-07-17 1967-06-13 United States Borax Chem Herbicidal composition and method employing substituted benzimidazoles
US3318889A (en) * 1963-10-14 1967-05-09 S B Penick & Company 2-benzimidazole carbamates
DE2014293A1 (de) * 1969-03-29 1970-10-08 Fisons Ltd., Felixstowe, Suffolk (Grossbritannien) Substituierte Benzimidazole und Verfahren zu ihrer Herstellung und Verwendung
CH528514A (de) * 1969-05-22 1972-09-30 Bayer Ag Verfahren zur Herstellung von Acylimidazolen
US3661925A (en) * 1970-05-15 1972-05-09 American Home Prod Process for the preparation of 2-benzimidazolecarboxamides
FR2115067B1 (es) * 1970-11-27 1974-03-22 Delalande Sa
DE2861987D1 (en) * 1977-08-01 1982-09-30 Ciba Geigy Ag Benzimidazole-2 derivatives, their preparation and their use for the preparation of medicaments

Also Published As

Publication number Publication date
AU3847878A (en) 1980-02-07
AR227125A1 (es) 1982-09-30
IE781545L (en) 1979-02-01
DD138318A5 (de) 1979-10-24
AU523324B2 (en) 1982-07-22
ES472208A1 (es) 1979-03-16
GR77614B (es) 1984-09-25
ATA553978A (de) 1981-04-15
US4323688A (en) 1982-04-06
DE2861987D1 (en) 1982-09-30
EP0000574B1 (de) 1982-08-04
IL55253A0 (en) 1978-09-29
NO782615L (no) 1979-02-02
NZ188006A (en) 1981-11-19
AR231636A1 (es) 1985-01-31
FI68231B (fi) 1985-04-30
CA1109072A (en) 1981-09-15
IE47285B1 (en) 1984-02-08
NO150082B (no) 1984-05-07
AT364830B (de) 1981-11-25
FI68231C (fi) 1985-08-12
JPS5427565A (en) 1979-03-01
DK339578A (da) 1979-02-02
PL208772A1 (pl) 1979-06-04
NO150082C (no) 1984-08-15
AR228023A1 (es) 1983-01-14
FI782348A (fi) 1979-02-02
EP0000574A1 (de) 1979-02-07
PT68365A (de) 1978-08-01
AR223196A1 (es) 1981-07-31

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