IL51388A - Fused pyrimidine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Fused pyrimidine derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL51388A
IL51388A IL51388A IL5138877A IL51388A IL 51388 A IL51388 A IL 51388A IL 51388 A IL51388 A IL 51388A IL 5138877 A IL5138877 A IL 5138877A IL 51388 A IL51388 A IL 51388A
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
pyrimidine derivatives
fused pyrimidine
Prior art date
Application number
IL51388A
Other languages
English (en)
Other versions
IL51388A0 (en
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of IL51388A0 publication Critical patent/IL51388A0/xx
Publication of IL51388A publication Critical patent/IL51388A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL51388A 1976-02-12 1977-02-04 Fused pyrimidine derivatives,their preparation and pharmaceutical compositions containing them IL51388A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU76CI1642A HU174693B (hu) 1976-02-12 1976-02-12 Sposob poluchenija kondensirovannykh proizvodnykh pirimidina

Publications (2)

Publication Number Publication Date
IL51388A0 IL51388A0 (en) 1977-04-29
IL51388A true IL51388A (en) 1981-07-31

Family

ID=10994601

Family Applications (1)

Application Number Title Priority Date Filing Date
IL51388A IL51388A (en) 1976-02-12 1977-02-04 Fused pyrimidine derivatives,their preparation and pharmaceutical compositions containing them

Country Status (28)

Country Link
US (2) US4123533A (sv)
JP (1) JPS5297996A (sv)
AR (1) AR220675A1 (sv)
AT (1) AT357539B (sv)
AU (1) AU512470B2 (sv)
BE (1) BE851346A (sv)
BG (1) BG29723A3 (sv)
CA (1) CA1082699A (sv)
CH (1) CH637651A5 (sv)
CS (1) CS199288B2 (sv)
DD (1) DD131557A5 (sv)
DE (1) DE2705778A1 (sv)
DK (1) DK152431C (sv)
ES (1) ES455800A1 (sv)
FI (1) FI63574C (sv)
FR (1) FR2340945A1 (sv)
GB (1) GB1554370A (sv)
GR (1) GR62466B (sv)
HU (1) HU174693B (sv)
IL (1) IL51388A (sv)
IN (1) IN146173B (sv)
NL (1) NL7701461A (sv)
NO (1) NO146775C (sv)
PL (1) PL109346B1 (sv)
PT (1) PT66184B (sv)
SE (1) SE431334B (sv)
SU (1) SU969165A3 (sv)
YU (1) YU33777A (sv)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU173438B (hu) * 1975-11-27 1979-05-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija novykh proizvodnykh 4-okso-1,6,7,8-/tetragidro-4h-pirido/1,2/pirimidina s zaderzhivajuhhejj vozgoranie aktivnot'ju i protivosvertivajuhhem effektom
HU185925B (en) * 1977-12-29 1985-04-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing compounds with nitrogen bridge head
HU180439B (en) * 1977-12-29 1983-03-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 9-amino-pyrido-square bracket-1,2-a-square bracket closed-pyrimidine derivatives
HU180701B (en) * 1977-12-29 1983-04-29 Chinoin Gyogyszer Es Vegyeszet Process for preparing pyrido-/1,2-a/pyrimidines containing a carboxylic or ester group on the pirimidimering
HU178496B (en) * 1977-12-29 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity
HU184058B (en) * 1977-12-29 1984-06-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing new compounds with nitrogen bridge head
US4642384A (en) * 1979-03-19 1987-02-10 Riker Laboratories, Inc. Process for the preparation of derivatives of pyrrolidine and piperidine
AT370731B (de) * 1979-05-02 1983-04-25 Chinoin Gyogyszer Es Vegyeszet Verfahren zur herstellung von neuen kondensierten pyrimidin-derivaten sowie von deren optischen antipoden und salzen
HU183408B (en) * 1981-04-28 1984-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing oral ratard pharmaceutical compositions
AT377586B (de) 1981-06-30 1985-04-10 Erba Farmitalia Verfahren zur herstellung von substituierten pyrrolo-(2,1-b)-chinazolinen und pyrido(2,1-b)chinazolinen
ES8406476A1 (es) * 1982-04-29 1984-07-01 Erba Farmitalia Procedimiento para preparar derivados cicloalifaticos condensados de pirido(1,2-a)pirimidinas sustituidas.
IL69274A (en) * 1982-08-05 1986-08-31 Erba Farmitalia (substituted amino)derivatives of 3-benzylidene-pyrrolo(2,1-b)quinazolin-9-ones and 6-benzylidene-pyrido(2,1-b)quinazolin-11-ones,their preparation and pharmaceutical compositions containing them
US5252572A (en) * 1988-02-03 1993-10-12 Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt. Pyridopyrimidine derivatives, pharmaceutical compositions containing them and process for preparing same
EP1539762A2 (en) * 2002-06-26 2005-06-15 Bristol-Myers Squibb Company Bicyclic pyrimidinones as coagulation cascade inhibitors

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3376304A (en) * 1962-03-14 1968-04-02 Mcneilab Inc 2-(r-r1-r2-methyl)-6-r3-6-r4-fulvenes
US3907798A (en) * 1966-06-15 1975-09-23 Sterling Drug Inc Preparation of 4H-pyrido{8 1,2-a{9 pyrimidin-4-ones from cyclic alkylidene 2-pyridylaminomethylenemalonates
AT286990B (de) * 1966-11-02 1971-01-11 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von neuen Homopyrimidazol-Derivaten sowie von deren Salzen
US3567719A (en) * 1967-05-17 1971-03-02 Eastman Kodak Co Methods for preparing dyes and novel dye intermediates
US3635956A (en) * 1968-03-01 1972-01-18 Squibb & Sons Inc Benzothiazines related compounds derivatives and salts thereof
FR2187311B1 (sv) * 1972-06-02 1975-06-20 Bouchara Emile
HU168014B (sv) * 1973-03-30 1976-02-28
US3897420A (en) * 1973-06-28 1975-07-29 Squibb & Sons Inc 2-Aminoalkyl-7-substituted-3,3a,4,5,6,7-hexahydro-3-substituted-2H-pyrazolo(4,3-c)pyridines
US3929787A (en) * 1974-04-22 1975-12-30 Squibb & Sons Inc 6,7,8,9-Tetrahydro-pyrido(1,2-a)pyrimidin-4-ones
DE2427614A1 (de) * 1974-06-07 1976-01-02 Gruenenthal Chemie Neue pyrrolderivate und verfahren zu ihrer herstellung
US3898224A (en) * 1974-09-09 1975-08-05 Squibb & Sons Inc 1,6,7,8-Tetrahydro-4-oxo-4H-pyrido {8 1,2-A{9 pyrimidine-9-carboalkoxy compounds
US3965100A (en) * 1975-02-26 1976-06-22 E. R. Squibb & Sons, Inc. 2,3-Dihydrocyclopenta[d]pyrido[1,2-a]pyrimidin-10(1H)-one and its derivatives
US3935197A (en) * 1975-05-16 1976-01-27 E. R. Squibb & Sons, Inc. 2-Styryl-4H-pyrido(1,2-a)pyrimidin-4-ones

Also Published As

Publication number Publication date
PT66184A (pt) 1977-03-01
SE431334B (sv) 1984-01-30
DD131557A5 (de) 1978-07-05
FI63574C (fi) 1983-07-11
CH637651A5 (de) 1983-08-15
FR2340945B1 (sv) 1981-11-27
IL51388A0 (en) 1977-04-29
NL7701461A (nl) 1977-08-16
US4252807A (en) 1981-02-24
JPS5297996A (en) 1977-08-17
ES455800A1 (es) 1978-07-01
AR220675A1 (es) 1980-11-28
BE851346A (fr) 1977-05-31
BG29723A3 (en) 1981-01-15
PT66184B (pt) 1978-07-11
DE2705778C2 (sv) 1990-11-29
FI63574B (fi) 1983-03-31
DK152431C (da) 1988-08-01
NO146775C (no) 1982-12-08
YU33777A (en) 1983-02-28
SE7701375L (sv) 1977-08-13
HU174693B (hu) 1980-03-28
DE2705778A1 (de) 1977-08-18
JPS6228793B2 (sv) 1987-06-23
US4123533A (en) 1978-10-31
FI770453A (sv) 1977-08-13
PL109346B1 (en) 1980-05-31
FR2340945A1 (fr) 1977-09-09
CA1082699A (en) 1980-07-29
AU512470B2 (en) 1980-10-16
SU969165A3 (ru) 1982-10-23
IN146173B (sv) 1979-03-10
DK152431B (da) 1988-02-29
GR62466B (en) 1979-04-13
AT357539B (de) 1980-07-10
NO146775B (no) 1982-08-30
DK59177A (da) 1977-08-13
CS199288B2 (en) 1980-07-31
NO770457L (no) 1977-08-15
AU2217277A (en) 1978-08-17
ATA84277A (de) 1979-12-15
GB1554370A (en) 1979-10-17

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