BG29723A3 - Method for obtaining of condensated pyrimidine derivatives - Google Patents

Method for obtaining of condensated pyrimidine derivatives

Info

Publication number
BG29723A3
BG29723A3 BG035340A BG3534077A BG29723A3 BG 29723 A3 BG29723 A3 BG 29723A3 BG 035340 A BG035340 A BG 035340A BG 3534077 A BG3534077 A BG 3534077A BG 29723 A3 BG29723 A3 BG 29723A3
Authority
BG
Bulgaria
Prior art keywords
obtaining
pyrimidine derivatives
condensated
proven
formulated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
BG035340A
Other languages
Bulgarian (bg)
English (en)
Inventor
Istvan Hermecz
Zoltan Meszaros
Sandor Virag
Lelle Vasvary
Agnes Horvath
Jozsef Knoll
Gyula Sebestyen
Agoston David
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Gyogyszer-es Vegyeszeti
Original Assignee
Chinoin Gyogyszer-es Vegyeszeti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer-es Vegyeszeti filed Critical Chinoin Gyogyszer-es Vegyeszeti
Publication of BG29723A3 publication Critical patent/BG29723A3/xx
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG035340A 1976-02-12 1977-02-04 Method for obtaining of condensated pyrimidine derivatives Expired BG29723A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU76CI1642A HU174693B (hu) 1976-02-12 1976-02-12 Sposob poluchenija kondensirovannykh proizvodnykh pirimidina

Publications (1)

Publication Number Publication Date
BG29723A3 true BG29723A3 (en) 1981-01-15

Family

ID=10994601

Family Applications (1)

Application Number Title Priority Date Filing Date
BG035340A Expired BG29723A3 (en) 1976-02-12 1977-02-04 Method for obtaining of condensated pyrimidine derivatives

Country Status (28)

Country Link
US (2) US4123533A (xx)
JP (1) JPS5297996A (xx)
AR (1) AR220675A1 (xx)
AT (1) AT357539B (xx)
AU (1) AU512470B2 (xx)
BE (1) BE851346A (xx)
BG (1) BG29723A3 (xx)
CA (1) CA1082699A (xx)
CH (1) CH637651A5 (xx)
CS (1) CS199288B2 (xx)
DD (1) DD131557A5 (xx)
DE (1) DE2705778A1 (xx)
DK (1) DK152431C (xx)
ES (1) ES455800A1 (xx)
FI (1) FI63574C (xx)
FR (1) FR2340945A1 (xx)
GB (1) GB1554370A (xx)
GR (1) GR62466B (xx)
HU (1) HU174693B (xx)
IL (1) IL51388A (xx)
IN (1) IN146173B (xx)
NL (1) NL7701461A (xx)
NO (1) NO146775C (xx)
PL (1) PL109346B1 (xx)
PT (1) PT66184B (xx)
SE (1) SE431334B (xx)
SU (1) SU969165A3 (xx)
YU (1) YU33777A (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU173438B (hu) * 1975-11-27 1979-05-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija novykh proizvodnykh 4-okso-1,6,7,8-/tetragidro-4h-pirido/1,2/pirimidina s zaderzhivajuhhejj vozgoranie aktivnot'ju i protivosvertivajuhhem effektom
HU178496B (en) * 1977-12-29 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 6,7,8,9-tetrahydro-4h-pyrido/1,2-a/pyrimidine derivatives with antiallergic activity
HU180439B (en) * 1977-12-29 1983-03-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 9-amino-pyrido-square bracket-1,2-a-square bracket closed-pyrimidine derivatives
HU184058B (en) * 1977-12-29 1984-06-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing new compounds with nitrogen bridge head
HU180701B (en) * 1977-12-29 1983-04-29 Chinoin Gyogyszer Es Vegyeszet Process for preparing pyrido-/1,2-a/pyrimidines containing a carboxylic or ester group on the pirimidimering
HU185925B (en) * 1977-12-29 1985-04-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing compounds with nitrogen bridge head
US4642384A (en) * 1979-03-19 1987-02-10 Riker Laboratories, Inc. Process for the preparation of derivatives of pyrrolidine and piperidine
AT370731B (de) * 1979-05-02 1983-04-25 Chinoin Gyogyszer Es Vegyeszet Verfahren zur herstellung von neuen kondensierten pyrimidin-derivaten sowie von deren optischen antipoden und salzen
HU183408B (en) * 1981-04-28 1984-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing oral ratard pharmaceutical compositions
AT377586B (de) * 1981-06-30 1985-04-10 Erba Farmitalia Verfahren zur herstellung von substituierten pyrrolo-(2,1-b)-chinazolinen und pyrido(2,1-b)chinazolinen
ES521739A0 (es) * 1982-04-29 1984-07-01 Erba Farmitalia Procedimiento para preparar derivados cicloalifaticos condensados de pirido(1,2-a)pirimidinas sustituidas.
IL69274A (en) * 1982-08-05 1986-08-31 Erba Farmitalia (substituted amino)derivatives of 3-benzylidene-pyrrolo(2,1-b)quinazolin-9-ones and 6-benzylidene-pyrido(2,1-b)quinazolin-11-ones,their preparation and pharmaceutical compositions containing them
US5252572A (en) * 1988-02-03 1993-10-12 Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt. Pyridopyrimidine derivatives, pharmaceutical compositions containing them and process for preparing same
US7094783B2 (en) * 2002-06-26 2006-08-22 Bristol-Myers Squibb Company Bicyclic pyrimidinones as coagulation cascade inhibitors

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3376304A (en) * 1962-03-14 1968-04-02 Mcneilab Inc 2-(r-r1-r2-methyl)-6-r3-6-r4-fulvenes
US3907798A (en) * 1966-06-15 1975-09-23 Sterling Drug Inc Preparation of 4H-pyrido{8 1,2-a{9 pyrimidin-4-ones from cyclic alkylidene 2-pyridylaminomethylenemalonates
DE1670480C2 (de) * 1966-11-02 1983-06-01 Chinoin Gyógyszer és Vegyészeti Termékek Gyára R.T., 1045 Budapest Pyrido[1,2-a]pyrimidinderivate, Verfahren zu deren Herstellung sowie diese Verbindungen enthaltende pharmazeutische Präparate
US3567719A (en) * 1967-05-17 1971-03-02 Eastman Kodak Co Methods for preparing dyes and novel dye intermediates
US3635956A (en) * 1968-03-01 1972-01-18 Squibb & Sons Inc Benzothiazines related compounds derivatives and salts thereof
FR2187311B1 (xx) * 1972-06-02 1975-06-20 Bouchara Emile
HU168014B (xx) * 1973-03-30 1976-02-28
US3897420A (en) * 1973-06-28 1975-07-29 Squibb & Sons Inc 2-Aminoalkyl-7-substituted-3,3a,4,5,6,7-hexahydro-3-substituted-2H-pyrazolo(4,3-c)pyridines
US3929787A (en) * 1974-04-22 1975-12-30 Squibb & Sons Inc 6,7,8,9-Tetrahydro-pyrido(1,2-a)pyrimidin-4-ones
DE2427614A1 (de) * 1974-06-07 1976-01-02 Gruenenthal Chemie Neue pyrrolderivate und verfahren zu ihrer herstellung
US3898224A (en) * 1974-09-09 1975-08-05 Squibb & Sons Inc 1,6,7,8-Tetrahydro-4-oxo-4H-pyrido {8 1,2-A{9 pyrimidine-9-carboalkoxy compounds
US3965100A (en) * 1975-02-26 1976-06-22 E. R. Squibb & Sons, Inc. 2,3-Dihydrocyclopenta[d]pyrido[1,2-a]pyrimidin-10(1H)-one and its derivatives
US3935197A (en) * 1975-05-16 1976-01-27 E. R. Squibb & Sons, Inc. 2-Styryl-4H-pyrido(1,2-a)pyrimidin-4-ones

Also Published As

Publication number Publication date
FI63574C (fi) 1983-07-11
AT357539B (de) 1980-07-10
SE431334B (sv) 1984-01-30
SE7701375L (sv) 1977-08-13
DK59177A (da) 1977-08-13
JPS6228793B2 (xx) 1987-06-23
CH637651A5 (de) 1983-08-15
IL51388A (en) 1981-07-31
CA1082699A (en) 1980-07-29
HU174693B (hu) 1980-03-28
US4252807A (en) 1981-02-24
AR220675A1 (es) 1980-11-28
ES455800A1 (es) 1978-07-01
PL109346B1 (en) 1980-05-31
NO146775B (no) 1982-08-30
US4123533A (en) 1978-10-31
DE2705778C2 (xx) 1990-11-29
FI770453A (xx) 1977-08-13
CS199288B2 (en) 1980-07-31
PT66184B (pt) 1978-07-11
NL7701461A (nl) 1977-08-16
FR2340945B1 (xx) 1981-11-27
IL51388A0 (en) 1977-04-29
DK152431B (da) 1988-02-29
NO146775C (no) 1982-12-08
GR62466B (en) 1979-04-13
DE2705778A1 (de) 1977-08-18
DK152431C (da) 1988-08-01
AU2217277A (en) 1978-08-17
BE851346A (fr) 1977-05-31
IN146173B (xx) 1979-03-10
NO770457L (no) 1977-08-15
AU512470B2 (en) 1980-10-16
FI63574B (fi) 1983-03-31
ATA84277A (de) 1979-12-15
FR2340945A1 (fr) 1977-09-09
JPS5297996A (en) 1977-08-17
DD131557A5 (de) 1978-07-05
SU969165A3 (ru) 1982-10-23
PT66184A (pt) 1977-03-01
YU33777A (en) 1983-02-28
GB1554370A (en) 1979-10-17

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