IL47936A - Dipeptide- triazoly- and imidazolyl derivatives of benzophenone and pyridyl phenyl ketone their preparation and pharmaceutical compositions containing them - Google Patents
Dipeptide- triazoly- and imidazolyl derivatives of benzophenone and pyridyl phenyl ketone their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL47936A IL47936A IL47936A IL4793675A IL47936A IL 47936 A IL47936 A IL 47936A IL 47936 A IL47936 A IL 47936A IL 4793675 A IL4793675 A IL 4793675A IL 47936 A IL47936 A IL 47936A
- Authority
- IL
- Israel
- Prior art keywords
- triazoly
- dipeptide
- benzophenone
- preparation
- pharmaceutical compositions
- Prior art date
Links
- 239000012965 benzophenone Substances 0.000 title 1
- UGLNASZSIGGGKN-UHFFFAOYSA-N bis(2-pyridin-2-ylphenyl)methanone Chemical compound C=1C=CC=C(C=2N=CC=CC=2)C=1C(=O)C1=CC=CC=C1C1=CC=CC=N1 UGLNASZSIGGGKN-UHFFFAOYSA-N 0.000 title 1
- 125000002883 imidazolyl group Chemical group 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06043—Leu-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
- C07K5/06095—Arg-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyridine Compounds (AREA)
- Peptides Or Proteins (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB36567/74A GB1517164A (en) | 1974-08-20 | 1974-08-20 | Substituted-phenyl ketones and a process for the manufacture thereof |
| GB2182175 | 1975-05-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL47936A0 IL47936A0 (en) | 1975-11-25 |
| IL47936A true IL47936A (en) | 1980-01-31 |
Family
ID=26255542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL47936A IL47936A (en) | 1974-08-20 | 1975-08-18 | Dipeptide- triazoly- and imidazolyl derivatives of benzophenone and pyridyl phenyl ketone their preparation and pharmaceutical compositions containing them |
Country Status (19)
| Country | Link |
|---|---|
| JP (1) | JPS6018656B2 (da) |
| AR (1) | AR217041A1 (da) |
| AT (1) | AT348985B (da) |
| AU (1) | AU502104B2 (da) |
| CA (1) | CA1177069A (da) |
| CH (1) | CH620900A5 (da) |
| DD (1) | DD123086A5 (da) |
| DE (1) | DE2537069A1 (da) |
| DK (1) | DK149284C (da) |
| ES (1) | ES440315A1 (da) |
| FI (1) | FI66592C (da) |
| FR (1) | FR2282261A1 (da) |
| GB (1) | GB1517164A (da) |
| IL (1) | IL47936A (da) |
| LU (1) | LU73219A1 (da) |
| NL (1) | NL7509884A (da) |
| NO (1) | NO150199C (da) |
| PH (1) | PH16616A (da) |
| SE (1) | SE426319B (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2754112A1 (de) * | 1977-12-05 | 1979-06-13 | Kali Chemie Pharma Gmbh | 1,4-benzodiazepinderivate, ihre salze und diese verbindungen enthaltende arzneipraeparate |
| IN184976B (da) * | 1996-06-13 | 2000-10-14 | Ranbaxy Lab Ltd |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3709898A (en) * | 1971-02-09 | 1973-01-09 | Upjohn Co | Process for the production of triazolobenzodiazepines and intermediates |
| JPS526861B2 (da) * | 1972-05-27 | 1977-02-25 | ||
| ZA735932B (en) * | 1972-09-21 | 1974-07-31 | Hoffmann La Roche | Benzodiazepine derivatives |
-
1974
- 1974-08-20 GB GB36567/74A patent/GB1517164A/en not_active Expired
-
1975
- 1975-08-13 CH CH1053375A patent/CH620900A5/de not_active IP Right Cessation
- 1975-08-18 PH PH17475A patent/PH16616A/en unknown
- 1975-08-18 IL IL47936A patent/IL47936A/xx unknown
- 1975-08-19 AT AT642175A patent/AT348985B/de not_active IP Right Cessation
- 1975-08-19 SE SE7509268A patent/SE426319B/xx not_active IP Right Cessation
- 1975-08-19 ES ES440315A patent/ES440315A1/es not_active Expired
- 1975-08-19 AR AR260048A patent/AR217041A1/es active
- 1975-08-19 LU LU73219A patent/LU73219A1/xx unknown
- 1975-08-19 NO NO752876A patent/NO150199C/no unknown
- 1975-08-19 DD DD187930A patent/DD123086A5/xx unknown
- 1975-08-19 FR FR7525632A patent/FR2282261A1/fr active Granted
- 1975-08-19 JP JP50099885A patent/JPS6018656B2/ja not_active Expired
- 1975-08-19 DK DK373975A patent/DK149284C/da active
- 1975-08-19 AU AU84074/75A patent/AU502104B2/en not_active Expired
- 1975-08-19 CA CA000233720A patent/CA1177069A/en not_active Expired
- 1975-08-20 FI FI752350A patent/FI66592C/fi not_active IP Right Cessation
- 1975-08-20 NL NL7509884A patent/NL7509884A/xx not_active Application Discontinuation
- 1975-08-20 DE DE19752537069 patent/DE2537069A1/de active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| NO150199B (no) | 1984-05-28 |
| NO752876L (da) | 1976-02-23 |
| CA1177069A (en) | 1984-10-30 |
| DK373975A (da) | 1976-02-21 |
| AR217041A1 (es) | 1980-02-29 |
| GB1517164A (en) | 1978-07-12 |
| SE7509268L (sv) | 1976-02-23 |
| DE2537069A1 (de) | 1976-03-04 |
| ATA642175A (de) | 1978-08-15 |
| FI66592C (fi) | 1984-11-12 |
| FI752350A7 (da) | 1976-02-21 |
| AT348985B (de) | 1979-03-12 |
| SE426319B (sv) | 1982-12-27 |
| DK149284C (da) | 1986-10-13 |
| FI66592B (fi) | 1984-07-31 |
| NL7509884A (nl) | 1976-02-24 |
| JPS6018656B2 (ja) | 1985-05-11 |
| DK149284B (da) | 1986-04-21 |
| DD123086A5 (da) | 1976-11-20 |
| AU502104B2 (en) | 1979-07-12 |
| DE2537069C2 (da) | 1988-09-08 |
| JPS51125048A (en) | 1976-11-01 |
| CH620900A5 (en) | 1980-12-31 |
| NO150199C (no) | 1984-09-05 |
| FR2282261B1 (da) | 1978-11-10 |
| AU8407475A (en) | 1977-02-24 |
| PH16616A (en) | 1983-11-28 |
| IL47936A0 (en) | 1975-11-25 |
| LU73219A1 (da) | 1977-04-15 |
| FR2282261A1 (fr) | 1976-03-19 |
| ES440315A1 (es) | 1977-09-16 |
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