IL47351A - Substituted 3-(2-(3-amino-2-hydroxy-propoxy)-phenyl)6-hydrazino-pyridazines,their preparation and pharmaceutical compositions comprising them - Google Patents

Substituted 3-(2-(3-amino-2-hydroxy-propoxy)-phenyl)6-hydrazino-pyridazines,their preparation and pharmaceutical compositions comprising them

Info

Publication number
IL47351A
IL47351A IL47351A IL4735175A IL47351A IL 47351 A IL47351 A IL 47351A IL 47351 A IL47351 A IL 47351A IL 4735175 A IL4735175 A IL 4735175A IL 47351 A IL47351 A IL 47351A
Authority
IL
Israel
Prior art keywords
pyridazines
hydrazino
propoxy
hydroxy
phenyl
Prior art date
Application number
IL47351A
Other languages
English (en)
Other versions
IL47351A0 (en
Inventor
E Taylor
W Coates
R Slater
A Roe
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB26864/74A external-priority patent/GB1527712A/en
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of IL47351A0 publication Critical patent/IL47351A0/xx
Publication of IL47351A publication Critical patent/IL47351A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/40—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/12—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/18—Sulfur atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL47351A 1974-06-18 1975-05-26 Substituted 3-(2-(3-amino-2-hydroxy-propoxy)-phenyl)6-hydrazino-pyridazines,their preparation and pharmaceutical compositions comprising them IL47351A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB26864/74A GB1527712A (en) 1974-06-18 1974-06-18 Hydrazinopyridazines
GB2075 1975-01-02

Publications (2)

Publication Number Publication Date
IL47351A0 IL47351A0 (en) 1975-07-28
IL47351A true IL47351A (en) 1980-02-29

Family

ID=26235616

Family Applications (1)

Application Number Title Priority Date Filing Date
IL47351A IL47351A (en) 1974-06-18 1975-05-26 Substituted 3-(2-(3-amino-2-hydroxy-propoxy)-phenyl)6-hydrazino-pyridazines,their preparation and pharmaceutical compositions comprising them

Country Status (15)

Country Link
US (1) US4053601A (fr)
JP (1) JPS5113782A (fr)
CA (1) CA1067078A (fr)
CH (1) CH617429A5 (fr)
DE (1) DE2527066A1 (fr)
DK (1) DK145099C (fr)
ES (1) ES438685A1 (fr)
FI (1) FI62532C (fr)
FR (1) FR2275213A1 (fr)
IE (1) IE42214B1 (fr)
IL (1) IL47351A (fr)
LU (1) LU72739A1 (fr)
NL (1) NL7507267A (fr)
SE (1) SE416650B (fr)
SU (1) SU862824A3 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4314943A (en) * 1977-07-13 1982-02-09 Mead Johnson & Company Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols
US4272440A (en) * 1978-02-24 1981-06-09 Smithkline Corporation Intermediates for preparing hydroxyphenylpyridazinones
IN148775B (fr) * 1978-08-04 1981-06-13 Smithkline & French Lab Ltd Uk
US4495352A (en) * 1979-02-13 1985-01-22 Mead Johnson & Company Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols
DE3028453A1 (de) * 1980-07-26 1982-03-18 Zinser Textilmaschinen Gmbh, 7333 Ebersbach Spinnmaschine
US4340733A (en) * 1980-09-02 1982-07-20 Smithkline Corporation Process for preparing 3-chloro-6-(2-hydroxyphenyl)-pyridazines
EP0101156A3 (fr) * 1982-06-24 1984-08-22 Smith Kline & French Laboratories Limited Procédé pour la préparation de 6-(2-hydroxyphényl)-3-pyridazinone
DE3302442A1 (de) * 1983-01-26 1984-07-26 Basf Ag, 6700 Ludwigshafen Neue pyridazinone, verfahren zu ihrer herstellung, diese verbindungen enthaltende therapeutische mittel und deren verwendung
GB8323553D0 (en) * 1983-09-02 1983-10-05 Smith Kline French Lab Pharmaceutical compositions
JPH0629254B2 (ja) * 1986-09-08 1994-04-20 帝国臓器製薬株式会社 ピリダジノン誘導体
CN100344616C (zh) 2001-06-12 2007-10-24 维尔斯达医疗公司 用于治疗代谢失调的化合物
MX2009000884A (es) * 2006-07-25 2009-06-05 Cephalon Inc Derivados de piridizinona.
EP2804603A1 (fr) 2012-01-10 2014-11-26 President and Fellows of Harvard College Composés promoteurs de réplication des cellules bêta et leurs procédés d'utilisation
TW202216671A (zh) * 2020-06-25 2022-05-01 瑞士商諾華公司 １，４—二取代的嗒𠯤化合物之製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE758146A (fr) * 1969-10-29 1971-04-28 Smith Kline French Lab Derives de l'amidine
US3818097A (en) * 1969-10-29 1974-06-18 Smith Kline French Lab Method of inhibiting histamine activity with isothioureas
IT1054107B (it) * 1970-12-15 1981-11-10 Isf Spa Nuove 3,idrazinopiridazine 6,sostituite ad attivita antiiperten siva e loro preparazione
US3975530A (en) * 1972-09-05 1976-08-17 Smith Kline & French Laboratories Limited N-cyano-N'-heterocyclic-alkyl quanidine inhibitors of H2 histamine receptors

Also Published As

Publication number Publication date
CH617429A5 (fr) 1980-05-30
US4053601A (en) 1977-10-11
DK145099C (da) 1983-01-31
DE2527066A1 (de) 1976-01-08
IL47351A0 (en) 1975-07-28
SE7506947L (sv) 1975-12-19
SE416650B (sv) 1981-01-26
DK245275A (da) 1975-12-19
FR2275213B1 (fr) 1979-08-10
SU862824A3 (ru) 1981-09-07
JPS5113782A (fr) 1976-02-03
FI62532B (fi) 1982-09-30
FI62532C (fi) 1983-01-10
NL7507267A (nl) 1975-12-22
AU8158175A (en) 1976-12-02
IE42214B1 (en) 1980-07-02
IE42214L (en) 1975-12-18
DK145099B (da) 1982-08-30
FR2275213A1 (fr) 1976-01-16
CA1067078A (fr) 1979-11-27
FI751790A (fr) 1975-12-19
ES438685A1 (es) 1977-05-16
LU72739A1 (fr) 1975-10-08

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