NL7507267A - Werkwijze ter bereiding van verbindingen met (beta)-adre- nergisch blokkerende en vasodilatorische werking. - Google Patents

Werkwijze ter bereiding van verbindingen met (beta)-adre- nergisch blokkerende en vasodilatorische werking.

Info

Publication number
NL7507267A
NL7507267A NL7507267A NL7507267A NL7507267A NL 7507267 A NL7507267 A NL 7507267A NL 7507267 A NL7507267 A NL 7507267A NL 7507267 A NL7507267 A NL 7507267A NL 7507267 A NL7507267 A NL 7507267A
Authority
NL
Netherlands
Prior art keywords
addressiclocking
beta
vasodilator action
connections
preparing
Prior art date
Application number
NL7507267A
Other languages
English (en)
Dutch (nl)
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB26864/74A external-priority patent/GB1527712A/en
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of NL7507267A publication Critical patent/NL7507267A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/76Unsaturated compounds containing keto groups
    • C07C59/90Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/40Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/12Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/18Sulfur atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NL7507267A 1974-06-18 1975-06-18 Werkwijze ter bereiding van verbindingen met (beta)-adre- nergisch blokkerende en vasodilatorische werking. NL7507267A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB26864/74A GB1527712A (en) 1974-06-18 1974-06-18 Hydrazinopyridazines
GB2075 1975-01-02

Publications (1)

Publication Number Publication Date
NL7507267A true NL7507267A (nl) 1975-12-22

Family

ID=26235616

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7507267A NL7507267A (nl) 1974-06-18 1975-06-18 Werkwijze ter bereiding van verbindingen met (beta)-adre- nergisch blokkerende en vasodilatorische werking.

Country Status (15)

Country Link
US (1) US4053601A (xx)
JP (1) JPS5113782A (xx)
CA (1) CA1067078A (xx)
CH (1) CH617429A5 (xx)
DE (1) DE2527066A1 (xx)
DK (1) DK145099C (xx)
ES (1) ES438685A1 (xx)
FI (1) FI62532C (xx)
FR (1) FR2275213A1 (xx)
IE (1) IE42214B1 (xx)
IL (1) IL47351A (xx)
LU (1) LU72739A1 (xx)
NL (1) NL7507267A (xx)
SE (1) SE416650B (xx)
SU (1) SU862824A3 (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4314943A (en) * 1977-07-13 1982-02-09 Mead Johnson & Company Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols
US4272440A (en) * 1978-02-24 1981-06-09 Smithkline Corporation Intermediates for preparing hydroxyphenylpyridazinones
IN148775B (xx) * 1978-08-04 1981-06-13 Smithkline & French Lab Ltd Uk
US4495352A (en) * 1979-02-13 1985-01-22 Mead Johnson & Company Heterocyclic substituted aryloxy 3-indolyl-tertiary butylaminopropanols
DE3028453A1 (de) * 1980-07-26 1982-03-18 Zinser Textilmaschinen Gmbh, 7333 Ebersbach Spinnmaschine
US4340733A (en) * 1980-09-02 1982-07-20 Smithkline Corporation Process for preparing 3-chloro-6-(2-hydroxyphenyl)-pyridazines
EP0101156A3 (en) * 1982-06-24 1984-08-22 Smith Kline & French Laboratories Limited Process for preparing 6-(2-hydroxyphenyl)-3-pyridazinone
DE3302442A1 (de) * 1983-01-26 1984-07-26 Basf Ag, 6700 Ludwigshafen Neue pyridazinone, verfahren zu ihrer herstellung, diese verbindungen enthaltende therapeutische mittel und deren verwendung
GB8323553D0 (en) * 1983-09-02 1983-10-05 Smith Kline French Lab Pharmaceutical compositions
JPH0629254B2 (ja) * 1986-09-08 1994-04-20 帝国臓器製薬株式会社 ピリダジノン誘導体
CN100344616C (zh) 2001-06-12 2007-10-24 维尔斯达医疗公司 用于治疗代谢失调的化合物
MX2009000884A (es) * 2006-07-25 2009-06-05 Cephalon Inc Derivados de piridizinona.
EP2804603A1 (en) 2012-01-10 2014-11-26 President and Fellows of Harvard College Beta-cell replication promoting compounds and methods of their use
TW202216671A (zh) * 2020-06-25 2022-05-01 瑞士商諾華公司 1,4—二取代的嗒𠯤化合物之製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE758146A (fr) * 1969-10-29 1971-04-28 Smith Kline French Lab Derives de l'amidine
US3818097A (en) * 1969-10-29 1974-06-18 Smith Kline French Lab Method of inhibiting histamine activity with isothioureas
IT1054107B (it) * 1970-12-15 1981-11-10 Isf Spa Nuove 3,idrazinopiridazine 6,sostituite ad attivita antiiperten siva e loro preparazione
US3975530A (en) * 1972-09-05 1976-08-17 Smith Kline & French Laboratories Limited N-cyano-N'-heterocyclic-alkyl quanidine inhibitors of H2 histamine receptors

Also Published As

Publication number Publication date
CH617429A5 (xx) 1980-05-30
US4053601A (en) 1977-10-11
DK145099C (da) 1983-01-31
DE2527066A1 (de) 1976-01-08
IL47351A0 (en) 1975-07-28
SE7506947L (sv) 1975-12-19
SE416650B (sv) 1981-01-26
DK245275A (da) 1975-12-19
FR2275213B1 (xx) 1979-08-10
SU862824A3 (ru) 1981-09-07
JPS5113782A (xx) 1976-02-03
FI62532B (fi) 1982-09-30
FI62532C (fi) 1983-01-10
AU8158175A (en) 1976-12-02
IE42214B1 (en) 1980-07-02
IE42214L (en) 1975-12-18
IL47351A (en) 1980-02-29
DK145099B (da) 1982-08-30
FR2275213A1 (fr) 1976-01-16
CA1067078A (en) 1979-11-27
FI751790A (xx) 1975-12-19
ES438685A1 (es) 1977-05-16
LU72739A1 (xx) 1975-10-08

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Legal Events

Date Code Title Description
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
BV The patent application has lapsed