IL46102A - Process for the preparation of 6,7-dimethoxy-4-amino-2-piperazin-1-yl quinazoline derivatives - Google Patents

Process for the preparation of 6,7-dimethoxy-4-amino-2-piperazin-1-yl quinazoline derivatives

Info

Publication number
IL46102A
IL46102A IL46102A IL4610274A IL46102A IL 46102 A IL46102 A IL 46102A IL 46102 A IL46102 A IL 46102A IL 4610274 A IL4610274 A IL 4610274A IL 46102 A IL46102 A IL 46102A
Authority
IL
Israel
Prior art keywords
reaction
piperazin
amino
dimethoxy
formula
Prior art date
Application number
IL46102A
Other languages
English (en)
Other versions
IL46102A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL46102A0 publication Critical patent/IL46102A0/xx
Publication of IL46102A publication Critical patent/IL46102A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
IL46102A 1973-12-05 1974-11-21 Process for the preparation of 6,7-dimethoxy-4-amino-2-piperazin-1-yl quinazoline derivatives IL46102A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/421,992 US3935213A (en) 1973-12-05 1973-12-05 Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives

Publications (2)

Publication Number Publication Date
IL46102A0 IL46102A0 (en) 1975-02-10
IL46102A true IL46102A (en) 1977-12-30

Family

ID=23672938

Family Applications (1)

Application Number Title Priority Date Filing Date
IL46102A IL46102A (en) 1973-12-05 1974-11-21 Process for the preparation of 6,7-dimethoxy-4-amino-2-piperazin-1-yl quinazoline derivatives

Country Status (32)

Country Link
US (1) US3935213A (fi)
JP (1) JPS5093987A (fi)
AR (1) AR207766A1 (fi)
AT (1) AT342598B (fi)
BE (1) BE822873A (fi)
CA (1) CA1010866A (fi)
CH (1) CH587843A5 (fi)
CS (1) CS189678B2 (fi)
DD (1) DD114950A5 (fi)
DE (1) DE2457911A1 (fi)
DK (1) DK135376B (fi)
EG (1) EG11404A (fi)
ES (1) ES432483A1 (fi)
FI (1) FI59799B (fi)
FR (1) FR2253750B1 (fi)
GB (1) GB1464583A (fi)
HK (1) HK28379A (fi)
IE (1) IE40204B1 (fi)
IL (1) IL46102A (fi)
IN (1) IN140460B (fi)
KE (1) KE2933A (fi)
LU (1) LU71427A1 (fi)
MY (1) MY7900247A (fi)
NL (1) NL7415793A (fi)
NO (1) NO141898C (fi)
PH (1) PH10594A (fi)
PL (1) PL94120B1 (fi)
RO (1) RO65957A (fi)
SE (1) SE411348B (fi)
SU (1) SU563914A3 (fi)
YU (1) YU36948B (fi)
ZA (1) ZA747593B (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4060615A (en) * 1976-02-18 1977-11-29 Mead Johnson & Company 2-Piperazinyl-6,7-dimethoxyquinazolines
US4001238A (en) * 1976-02-18 1977-01-04 Bristol-Myers Company 1,3,4-oxadiazole amides
US4001237A (en) * 1976-02-18 1977-01-04 Bristol-Myers Company Oxazole, isoxazole, thiazole and isothiazole amides
SE435380B (sv) 1976-06-15 1984-09-24 Pfizer Forfarande for framstellning av kinazolinforeningar
US4062844A (en) * 1976-09-20 1977-12-13 Pfizer Inc. Process for preparing hypotensive 2-(4-aroylpiperazin-1-yl)-amino-6,7-dimethoxyquinazolines
FI58125C (fi) * 1976-12-15 1985-01-02 Orion Yhtymae Oy Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolin med blodtryckssaenkande vekan
FI58124C (fi) * 1976-12-15 1980-12-10 Orion Yhtymae Oy Ny mellanprodukt 3,4-dimetoxi-6-(4-(2-furoyl)-1-piperazinyltiokarbamido)-bensonitril foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolin med blodtryckssaenkande verkan
US4138561A (en) * 1977-09-30 1979-02-06 Bristol-Myers Company Cyanocarboxamidines and quinazoline process
DK153878C (da) * 1978-05-18 1989-02-06 Pfizer Fremgangsmaade til fremstilling af 2'-methyl-2'-hydroxy-propyl-piperazin-1-carboxylatforbindelser
FI67699C (fi) * 1979-01-31 1985-05-10 Orion Yhtymae Oy Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolinhydroklorid med blodtryckssaenkande verkan
GB2068961B (en) 1980-02-13 1983-11-30 Sankyo Co Quinazoline derivatives
US4333937A (en) * 1980-04-18 1982-06-08 American Home Products Corp. 2-(Piperazinyl)-4-pyrimioinamines
US4351832A (en) * 1980-04-18 1982-09-28 American Home Products Corporation 2-(Piperazinyl)-4-pyrimidinamines
FI70411C (fi) * 1980-12-29 1986-09-19 Pfizer Foerfarande foer framstaellning av nya antihypertensiva 4-amino-6,7-dimetoxi-2-piperazinokinazolin derivat
FI79107C (fi) * 1984-06-25 1989-11-10 Orion Yhtymae Oy Foerfarande foer framstaellning av stabil -form av prazosinhydroklorid.
CA2077252C (en) * 1992-08-31 2001-04-10 Khashayar Karimian Methods of making ureas and guanidines, and intermediates therefor
EP0794178A4 (en) * 1994-11-25 1998-02-25 Nippon Chemiphar Co CHINAZOLIN DERIVATIVES
US6313294B1 (en) 1998-02-04 2001-11-06 Development Center For Biotechnology Process for preparing amides
US20070086958A1 (en) * 2005-10-14 2007-04-19 Medafor, Incorporated Formation of medically useful gels comprising microporous particles and methods of use
US20070087061A1 (en) * 2005-10-14 2007-04-19 Medafor, Incorporated Method and composition for creating and/or activating a platelet-rich gel by contact with a porous particulate material, for use in wound care, tissue adhesion, or as a matrix for delivery of therapeutic components

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511836A (en) * 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines

Also Published As

Publication number Publication date
AU7553874A (en) 1976-05-20
IL46102A0 (en) 1975-02-10
FR2253750A1 (fi) 1975-07-04
YU36948B (en) 1984-08-31
PH10594A (en) 1977-07-15
ZA747593B (en) 1975-12-31
PL94120B1 (fi) 1977-07-30
KE2933A (en) 1979-03-30
US3935213A (en) 1976-01-27
DK135376B (da) 1977-04-18
SU563914A3 (ru) 1977-06-30
NO141898B (no) 1980-02-18
IE40204L (en) 1975-06-05
RO65957A (fr) 1979-07-15
SE411348B (sv) 1979-12-17
EG11404A (en) 1978-03-29
AR207766A1 (es) 1976-10-29
MY7900247A (en) 1979-12-31
LU71427A1 (fi) 1975-08-20
ES432483A1 (es) 1976-11-16
FI59799B (fi) 1981-06-30
FR2253750B1 (fi) 1977-10-28
DE2457911A1 (de) 1975-06-12
CH587843A5 (fi) 1977-05-13
AT342598B (de) 1978-04-10
NO141898C (no) 1980-06-04
FI351474A (fi) 1975-06-06
DK629874A (fi) 1975-07-21
NO744382L (fi) 1975-06-30
YU317874A (en) 1982-06-18
GB1464583A (en) 1977-02-16
DD114950A5 (fi) 1975-09-05
IE40204B1 (en) 1979-04-11
CS189678B2 (en) 1979-04-30
DK135376C (fi) 1977-09-26
SE7413960L (fi) 1975-06-06
BE822873A (fr) 1975-06-03
NL7415793A (nl) 1975-06-09
HK28379A (en) 1979-05-11
IN140460B (fi) 1976-11-13
CA1010866A (en) 1977-05-24
JPS5093987A (fi) 1975-07-26
ATA970274A (de) 1977-08-15

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