IL45880A - 3-phenyl-1,2-benzisoxyzole derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

3-phenyl-1,2-benzisoxyzole derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL45880A
IL45880A IL45880A IL4588074A IL45880A IL 45880 A IL45880 A IL 45880A IL 45880 A IL45880 A IL 45880A IL 4588074 A IL4588074 A IL 4588074A IL 45880 A IL45880 A IL 45880A
Authority
IL
Israel
Prior art keywords
benzisoxyzole
phenyl
derivatives
preparation
pharmaceutical compositions
Prior art date
Application number
IL45880A
Other languages
English (en)
Other versions
IL45880A0 (en
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Priority to IL52180A priority Critical patent/IL52180A/xx
Priority to IL52179A priority patent/IL52179A/xx
Publication of IL45880A0 publication Critical patent/IL45880A0/xx
Publication of IL45880A publication Critical patent/IL45880A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D263/57—Aryl or substituted aryl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL45880A 1973-10-23 1974-10-18 3-phenyl-1,2-benzisoxyzole derivatives,their preparation and pharmaceutical compositions containing them IL45880A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IL52180A IL52180A (en) 1973-10-23 1974-10-18 Process for preparing a 5-or 6- substituted 2-phenylbenzoxazole
IL52179A IL52179A (en) 1973-10-23 1974-10-18 Benzophenone oximes and hydrazones and their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB49259/73A GB1488003A (en) 1973-10-23 1973-10-23 1,2-benzisoxazole derivatives processes for their preparation and their use as pharmaceuticals

Publications (2)

Publication Number Publication Date
IL45880A0 IL45880A0 (en) 1974-12-31
IL45880A true IL45880A (en) 1979-09-30

Family

ID=10451720

Family Applications (3)

Application Number Title Priority Date Filing Date
IL45880A IL45880A (en) 1973-10-23 1974-10-18 3-phenyl-1,2-benzisoxyzole derivatives,their preparation and pharmaceutical compositions containing them
IL52180A IL52180A0 (en) 1973-10-23 1977-05-27 Process for preparing a 5-or 6-substituted benzoxazole
IL52179A IL52179A0 (en) 1973-10-23 1977-05-27 Novel benzophenone oximes and hydrazones and their preparation

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL52180A IL52180A0 (en) 1973-10-23 1977-05-27 Process for preparing a 5-or 6-substituted benzoxazole
IL52179A IL52179A0 (en) 1973-10-23 1977-05-27 Novel benzophenone oximes and hydrazones and their preparation

Country Status (27)

Country Link
US (1) US3951999A (ja)
JP (2) JPS5912671B2 (ja)
AR (3) AR209755A1 (ja)
AT (1) AT341520B (ja)
AU (1) AU510909B2 (ja)
BE (1) BE821406A (ja)
BG (2) BG25991A3 (ja)
CA (1) CA1042005A (ja)
CH (2) CH595360A5 (ja)
CS (1) CS189671B2 (ja)
DD (1) DD116830A5 (ja)
DE (1) DE2450053A1 (ja)
DK (1) DK552674A (ja)
ES (3) ES431247A1 (ja)
FR (3) FR2248041B1 (ja)
GB (1) GB1488003A (ja)
HU (1) HU171613B (ja)
IE (1) IE40078B1 (ja)
IL (3) IL45880A (ja)
NL (1) NL7413848A (ja)
NZ (1) NZ175780A (ja)
PH (1) PH11022A (ja)
RO (2) RO74031A (ja)
SE (3) SE424324B (ja)
SU (3) SU604491A3 (ja)
YU (1) YU282474A (ja)
ZA (1) ZA746594B (ja)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1590587A (en) * 1977-06-28 1981-06-03 Lilly Industries Ltd Benoxaprofen
US4728662A (en) * 1977-11-21 1988-03-01 Hoechst-Roussel Pharmaceuticals Inc. 1,2-benzisoxazoloxyacetic acids and related compounds
US4673746A (en) * 1978-10-06 1987-06-16 Hoechst-Roussel Pharmaceuticals, Inc. 1,2-benzisoxazoloxyacetic acids and related compounds
NZ189705A (en) * 1978-03-01 1981-07-13 Boots Co Ltd Benzophenone-hydrazone derivatives and pesticidal compositions intermediates
US4337261A (en) * 1980-07-28 1982-06-29 Hoechst-Roussel Pharmaceuticals Inc. (1,2-Benzisoxazol)phenoxyacetic acids as diuretics
US4894461A (en) * 1981-04-27 1990-01-16 Hoechst-Roussel Pharmaceuticals, Inc. 3-(γ-chloropropyl)-6-fluoro-1,2-benzisoxazole
US4396770A (en) * 1982-04-09 1983-08-02 Hoechst-Roussel Pharmaceuticals Inc. 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-hydroxy-4-phenylpiperidines
US4610988A (en) * 1982-04-09 1986-09-09 Hoechst-Roussel Pharmaceuticals Inc. 1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines useful for alleviating pain
US4458075A (en) * 1982-04-09 1984-07-03 Hoechst-Roussel Pharmaceuticals Inc. 6-Fluoro-3-[3-(1-heterocyclo)propyl]-1,2-benzisoxazoles
US4536578A (en) * 1982-04-09 1985-08-20 Hoechst-Roussel Pharmaceuticals Inc. 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines
US4374245A (en) * 1982-04-09 1983-02-15 Hoechst-Roussel Pharmaceuticals Inc. 8-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
US4609658A (en) * 1982-04-09 1986-09-02 Hoechst-Roussel Pharmaceuticals Inc. 1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted) piperazines useful for reducing blood pressure
US4390544A (en) * 1982-04-09 1983-06-28 Hoechst-Roussel Pharmaceuticals Inc. {1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(2-oxo-1-benzimidazolinyl}p
US4420485A (en) * 1982-09-29 1983-12-13 Hoechst-Roussel Pharmaceuticals Inc. 1'-[3-(1,2-Benzisoxazol-3-yl) proply]spiro[benzofuran-2(3H),3' or 4'-piperidines or 3'-pyrrolidines]
FR2540107B1 (fr) * 1983-01-28 1986-10-17 Inst Rech Chim Biolog Nouveaux derives d'halogenobenzophenone-oxime, utilisation en therapeutique et procede de preparation
FI92189C (fi) * 1986-03-17 1994-10-10 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisen difenyylimetaanijohdannaisen valmistamiseksi
US4898874A (en) * 1986-09-15 1990-02-06 A. H. Robins Company, Inc. Acetic acid derivatives of 3-aryl-2,1-benzisoxazole and esters and amides thereof
JPH037961U (ja) * 1989-06-14 1991-01-25
US5114960A (en) * 1989-07-20 1992-05-19 Hoffmann-La Roche Inc. Substituted isoxazole derivatives
KR101426093B1 (ko) * 2006-02-10 2014-08-01 서미트 코포레이션 피엘씨 뒤시엔느 근이영양증의 치료
WO2013038351A1 (en) * 2011-09-16 2013-03-21 Pfizer Inc. Solid forms of a transthyretin dissociation inhibitor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH1093669A4 (ja) * 1969-07-17 1971-02-15
FR2093173A5 (en) * 1970-06-04 1972-01-28 Gen Mills Inc Substituted 2-hydroxybenzophenoximes for - copper extraction

Also Published As

Publication number Publication date
ES449655A1 (es) 1977-07-01
NL7413848A (nl) 1975-04-25
SE7413237L (ja) 1975-04-24
FR2361359A1 (fr) 1978-03-10
HU171613B (hu) 1978-02-28
JPS5077364A (ja) 1975-06-24
PH11022A (en) 1977-10-25
BE821406A (fr) 1975-04-23
CA1042005A (en) 1978-11-07
DD116830A5 (ja) 1975-12-12
AU510909B2 (en) 1980-07-17
SU795459A3 (ru) 1981-01-07
FR2361328A1 (fr) 1978-03-10
BG25991A3 (bg) 1979-01-12
JPS57154174A (en) 1982-09-22
GB1488003A (en) 1977-10-05
AR221321A1 (es) 1981-01-30
FR2361359B1 (ja) 1979-07-20
SU608476A3 (ru) 1978-05-25
AT341520B (de) 1978-02-10
FR2248041B1 (ja) 1978-09-08
AR209755A1 (es) 1977-05-31
AU7454774A (en) 1976-04-29
ZA746594B (en) 1976-06-30
IL52179A0 (en) 1977-07-31
JPS5912671B2 (ja) 1984-03-24
RO74031A (ro) 1982-02-01
IE40078L (en) 1975-04-23
DK552674A (ja) 1975-06-16
SE424325B (sv) 1982-07-12
NZ175780A (en) 1978-04-03
RO78465A (ro) 1982-02-26
AU2880177A (en) 1979-03-15
YU282474A (en) 1982-02-28
SE424324B (sv) 1982-07-12
FR2248041A1 (ja) 1975-05-16
SE7710599L (sv) 1977-09-21
ES431247A1 (es) 1977-02-16
IE40078B1 (en) 1979-03-14
IL45880A0 (en) 1974-12-31
CH595360A5 (ja) 1978-02-15
CH605864A5 (ja) 1978-10-13
SU604491A3 (ru) 1978-04-25
IL52180A0 (en) 1977-07-31
JPS636066B2 (ja) 1988-02-08
SE7710600L (sv) 1977-09-21
BG26531A4 (bg) 1979-04-12
AR213086A1 (es) 1978-12-15
US3951999A (en) 1976-04-20
ATA852374A (de) 1977-06-15
FR2361328B1 (ja) 1979-07-13
ES449654A1 (es) 1977-07-01
CS189671B2 (en) 1979-04-30
SE435713B (sv) 1984-10-15
DE2450053A1 (de) 1975-04-24

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