CS189671B2 - Method of producin 3-phenyl-1,2-benzisoxazolylcarboxylic acid - Google Patents

Method of producin 3-phenyl-1,2-benzisoxazolylcarboxylic acid

Info

Publication number
CS189671B2
CS189671B2 CS747227A CS722774A CS189671B2 CS 189671 B2 CS189671 B2 CS 189671B2 CS 747227 A CS747227 A CS 747227A CS 722774 A CS722774 A CS 722774A CS 189671 B2 CS189671 B2 CS 189671B2
Authority
CS
Czechoslovakia
Prior art keywords
benzisoxazolylcarboxylic
producin
phenyl
acid
benzisoxazolylcarboxylic acid
Prior art date
Application number
CS747227A
Other languages
Czech (cs)
English (en)
Inventor
John Ch Saunders
William R N Williamson
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Priority to CS76603A priority Critical patent/CS189696B2/cs
Priority to CS76602A priority patent/CS189695B2/cs
Publication of CS189671B2 publication Critical patent/CS189671B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D263/57—Aryl or substituted aryl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CS747227A 1973-10-23 1974-10-22 Method of producin 3-phenyl-1,2-benzisoxazolylcarboxylic acid CS189671B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CS76603A CS189696B2 (en) 1973-10-23 1976-01-30 Method of producing novel oximes
CS76602A CS189695B2 (en) 1973-10-23 1976-01-30 Method of producing benzoxazoles substituted in position 5 or 6

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB49259/73A GB1488003A (en) 1973-10-23 1973-10-23 1,2-benzisoxazole derivatives processes for their preparation and their use as pharmaceuticals

Publications (1)

Publication Number Publication Date
CS189671B2 true CS189671B2 (en) 1979-04-30

Family

ID=10451720

Family Applications (1)

Application Number Title Priority Date Filing Date
CS747227A CS189671B2 (en) 1973-10-23 1974-10-22 Method of producin 3-phenyl-1,2-benzisoxazolylcarboxylic acid

Country Status (27)

Country Link
US (1) US3951999A (ja)
JP (2) JPS5912671B2 (ja)
AR (3) AR209755A1 (ja)
AT (1) AT341520B (ja)
AU (1) AU510909B2 (ja)
BE (1) BE821406A (ja)
BG (2) BG25991A3 (ja)
CA (1) CA1042005A (ja)
CH (2) CH595360A5 (ja)
CS (1) CS189671B2 (ja)
DD (1) DD116830A5 (ja)
DE (1) DE2450053A1 (ja)
DK (1) DK552674A (ja)
ES (3) ES431247A1 (ja)
FR (3) FR2248041B1 (ja)
GB (1) GB1488003A (ja)
HU (1) HU171613B (ja)
IE (1) IE40078B1 (ja)
IL (3) IL45880A (ja)
NL (1) NL7413848A (ja)
NZ (1) NZ175780A (ja)
PH (1) PH11022A (ja)
RO (2) RO74031A (ja)
SE (3) SE424324B (ja)
SU (3) SU604491A3 (ja)
YU (1) YU282474A (ja)
ZA (1) ZA746594B (ja)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1590587A (en) * 1977-06-28 1981-06-03 Lilly Industries Ltd Benoxaprofen
US4728662A (en) * 1977-11-21 1988-03-01 Hoechst-Roussel Pharmaceuticals Inc. 1,2-benzisoxazoloxyacetic acids and related compounds
US4673746A (en) * 1978-10-06 1987-06-16 Hoechst-Roussel Pharmaceuticals, Inc. 1,2-benzisoxazoloxyacetic acids and related compounds
NZ189705A (en) * 1978-03-01 1981-07-13 Boots Co Ltd Benzophenone-hydrazone derivatives and pesticidal compositions intermediates
US4337261A (en) * 1980-07-28 1982-06-29 Hoechst-Roussel Pharmaceuticals Inc. (1,2-Benzisoxazol)phenoxyacetic acids as diuretics
US4894461A (en) * 1981-04-27 1990-01-16 Hoechst-Roussel Pharmaceuticals, Inc. 3-(γ-chloropropyl)-6-fluoro-1,2-benzisoxazole
US4396770A (en) * 1982-04-09 1983-08-02 Hoechst-Roussel Pharmaceuticals Inc. 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-hydroxy-4-phenylpiperidines
US4610988A (en) * 1982-04-09 1986-09-09 Hoechst-Roussel Pharmaceuticals Inc. 1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines useful for alleviating pain
US4458075A (en) * 1982-04-09 1984-07-03 Hoechst-Roussel Pharmaceuticals Inc. 6-Fluoro-3-[3-(1-heterocyclo)propyl]-1,2-benzisoxazoles
US4536578A (en) * 1982-04-09 1985-08-20 Hoechst-Roussel Pharmaceuticals Inc. 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted)piperazines
US4374245A (en) * 1982-04-09 1983-02-15 Hoechst-Roussel Pharmaceuticals Inc. 8-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
US4609658A (en) * 1982-04-09 1986-09-02 Hoechst-Roussel Pharmaceuticals Inc. 1-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(substituted) piperazines useful for reducing blood pressure
US4390544A (en) * 1982-04-09 1983-06-28 Hoechst-Roussel Pharmaceuticals Inc. {1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(2-oxo-1-benzimidazolinyl}p
US4420485A (en) * 1982-09-29 1983-12-13 Hoechst-Roussel Pharmaceuticals Inc. 1'-[3-(1,2-Benzisoxazol-3-yl) proply]spiro[benzofuran-2(3H),3' or 4'-piperidines or 3'-pyrrolidines]
FR2540107B1 (fr) * 1983-01-28 1986-10-17 Inst Rech Chim Biolog Nouveaux derives d'halogenobenzophenone-oxime, utilisation en therapeutique et procede de preparation
FI92189C (fi) * 1986-03-17 1994-10-10 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisen difenyylimetaanijohdannaisen valmistamiseksi
US4898874A (en) * 1986-09-15 1990-02-06 A. H. Robins Company, Inc. Acetic acid derivatives of 3-aryl-2,1-benzisoxazole and esters and amides thereof
JPH037961U (ja) * 1989-06-14 1991-01-25
US5114960A (en) * 1989-07-20 1992-05-19 Hoffmann-La Roche Inc. Substituted isoxazole derivatives
KR101426093B1 (ko) * 2006-02-10 2014-08-01 서미트 코포레이션 피엘씨 뒤시엔느 근이영양증의 치료
WO2013038351A1 (en) * 2011-09-16 2013-03-21 Pfizer Inc. Solid forms of a transthyretin dissociation inhibitor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH1093669A4 (ja) * 1969-07-17 1971-02-15
FR2093173A5 (en) * 1970-06-04 1972-01-28 Gen Mills Inc Substituted 2-hydroxybenzophenoximes for - copper extraction

Also Published As

Publication number Publication date
ES449655A1 (es) 1977-07-01
NL7413848A (nl) 1975-04-25
SE7413237L (ja) 1975-04-24
FR2361359A1 (fr) 1978-03-10
HU171613B (hu) 1978-02-28
JPS5077364A (ja) 1975-06-24
PH11022A (en) 1977-10-25
BE821406A (fr) 1975-04-23
CA1042005A (en) 1978-11-07
DD116830A5 (ja) 1975-12-12
AU510909B2 (en) 1980-07-17
IL45880A (en) 1979-09-30
SU795459A3 (ru) 1981-01-07
FR2361328A1 (fr) 1978-03-10
BG25991A3 (bg) 1979-01-12
JPS57154174A (en) 1982-09-22
GB1488003A (en) 1977-10-05
AR221321A1 (es) 1981-01-30
FR2361359B1 (ja) 1979-07-20
SU608476A3 (ru) 1978-05-25
AT341520B (de) 1978-02-10
FR2248041B1 (ja) 1978-09-08
AR209755A1 (es) 1977-05-31
AU7454774A (en) 1976-04-29
ZA746594B (en) 1976-06-30
IL52179A0 (en) 1977-07-31
JPS5912671B2 (ja) 1984-03-24
RO74031A (ro) 1982-02-01
IE40078L (en) 1975-04-23
DK552674A (ja) 1975-06-16
SE424325B (sv) 1982-07-12
NZ175780A (en) 1978-04-03
RO78465A (ro) 1982-02-26
AU2880177A (en) 1979-03-15
YU282474A (en) 1982-02-28
SE424324B (sv) 1982-07-12
FR2248041A1 (ja) 1975-05-16
SE7710599L (sv) 1977-09-21
ES431247A1 (es) 1977-02-16
IE40078B1 (en) 1979-03-14
IL45880A0 (en) 1974-12-31
CH595360A5 (ja) 1978-02-15
CH605864A5 (ja) 1978-10-13
SU604491A3 (ru) 1978-04-25
IL52180A0 (en) 1977-07-31
JPS636066B2 (ja) 1988-02-08
SE7710600L (sv) 1977-09-21
BG26531A4 (bg) 1979-04-12
AR213086A1 (es) 1978-12-15
US3951999A (en) 1976-04-20
ATA852374A (de) 1977-06-15
FR2361328B1 (ja) 1979-07-13
ES449654A1 (es) 1977-07-01
SE435713B (sv) 1984-10-15
DE2450053A1 (de) 1975-04-24

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