IL45289A - Process for the preperation of optically active 5-phenyl-13-dihydro-2h-1,4-benzodiazepin-2-ones and certain novel derivatives of this type - Google Patents

Process for the preperation of optically active 5-phenyl-13-dihydro-2h-1,4-benzodiazepin-2-ones and certain novel derivatives of this type

Info

Publication number
IL45289A
IL45289A IL45289A IL4528974A IL45289A IL 45289 A IL45289 A IL 45289A IL 45289 A IL45289 A IL 45289A IL 4528974 A IL4528974 A IL 4528974A IL 45289 A IL45289 A IL 45289A
Authority
IL
Israel
Prior art keywords
preperation
benzodiazepin
dihydro
ones
phenyl
Prior art date
Application number
IL45289A
Other languages
English (en)
Other versions
IL45289A0 (en
Original Assignee
Crc Ricerca Chim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crc Ricerca Chim filed Critical Crc Ricerca Chim
Publication of IL45289A0 publication Critical patent/IL45289A0/xx
Publication of IL45289A publication Critical patent/IL45289A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/28Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL45289A 1973-07-30 1974-07-17 Process for the preperation of optically active 5-phenyl-13-dihydro-2h-1,4-benzodiazepin-2-ones and certain novel derivatives of this type IL45289A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1105673A CH573928A5 (de) 1973-07-30 1973-07-30

Publications (2)

Publication Number Publication Date
IL45289A0 IL45289A0 (en) 1974-10-22
IL45289A true IL45289A (en) 1979-12-30

Family

ID=4369623

Family Applications (1)

Application Number Title Priority Date Filing Date
IL45289A IL45289A (en) 1973-07-30 1974-07-17 Process for the preperation of optically active 5-phenyl-13-dihydro-2h-1,4-benzodiazepin-2-ones and certain novel derivatives of this type

Country Status (21)

Country Link
US (1) US4010153A (de)
JP (1) JPS5041886A (de)
AR (1) AR202224A1 (de)
AT (1) AT337192B (de)
BE (1) BE818047A (de)
CA (1) CA1021778A (de)
CH (1) CH573928A5 (de)
DE (1) DE2436744A1 (de)
DK (1) DK138798B (de)
ES (1) ES428675A1 (de)
FI (1) FI227474A (de)
FR (1) FR2239464B1 (de)
GB (1) GB1481219A (de)
HU (1) HU169180B (de)
IE (1) IE39904B1 (de)
IL (1) IL45289A (de)
NL (1) NL7410256A (de)
NO (1) NO137897C (de)
SE (2) SE7409708L (de)
SU (1) SU528872A3 (de)
ZA (1) ZA744635B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1332410C (en) * 1984-06-26 1994-10-11 Roger M. Freidinger Benzodiazepine analogs
US4820834A (en) * 1984-06-26 1989-04-11 Merck & Co., Inc. Benzodiazepine analogs
LT3324977T (lt) 2015-07-22 2022-10-25 Enanta Pharmaceuticals, Inc. Benzodiazepino dariniai kaip rsv inhibitoriai
US20170226129A1 (en) 2016-01-15 2017-08-10 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as rsv inhibitors
CA3065368A1 (en) 2017-02-16 2018-08-23 Enanta Pharmaceuticals, Inc. Processes for the preparation of benzodiazepine derivatives
WO2018226801A1 (en) 2017-06-07 2018-12-13 Enanta Pharmaceuticals, Inc. Aryldiazepine derivatives as rsv inhibitors
WO2019006295A1 (en) 2017-06-30 2019-01-03 Enanta Pharmaceuticals, Inc. HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS
US10851115B2 (en) 2017-06-30 2020-12-01 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as RSV inhibitors
BR112020006334A2 (pt) 2017-09-29 2020-09-24 Enanta Pharmaceuticals, Inc. combinação de agentes farmacêuticos como inibidores de rsv
WO2019094920A1 (en) 2017-11-13 2019-05-16 Enanta Pharmaceuticals, Inc. Azepin-2-one derivatives as rsv inhibitors
CA3080138A1 (en) * 2017-11-13 2019-05-16 Enanta Pharmaceuticals, Inc. Processes for the resolution of benzodiazepin-2-one and benzoazepin-2-one derivatives
WO2019199908A1 (en) 2018-04-11 2019-10-17 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as rsv inhibitors
UY38614A (es) 2019-03-18 2020-10-30 Enanta Pharm Inc Derivados de benzodiazepinas como inhibidores del rsv
US11179400B2 (en) 2019-04-09 2021-11-23 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as RSV inhibitors
US11505558B1 (en) 2019-10-04 2022-11-22 Enanta Pharmaceuticals, Inc. Antiviral heterocyclic compounds
UY39032A (es) 2020-01-24 2021-07-30 Enanta Pharm Inc Compuestos heterocíclicos como agentes antivirales
WO2022010882A1 (en) 2020-07-07 2022-01-13 Enanta Pharmaceuticals, Inc, Dihydroquinoxaline and dihydropyridopyrazine derivatives as rsv inhibitors
US11945824B2 (en) 2020-10-19 2024-04-02 Enanta Pharmaceuticals, Inc. Heterocyclic compounds as anti-viral agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3371085A (en) * 1959-12-10 1968-02-27 Hoffmann La Roche 5-aryl-3h-1,4-benzodiazepin-2(1h)-ones
JPS4426302Y1 (de) * 1966-04-22 1969-11-05

Also Published As

Publication number Publication date
FR2239464A1 (de) 1975-02-28
DK138798B (da) 1978-10-30
AT337192B (de) 1977-06-10
IE39904L (en) 1975-01-30
SE7409708L (de) 1975-01-31
SE7510823L (sv) 1975-09-26
ES428675A1 (es) 1976-09-01
IL45289A0 (en) 1974-10-22
ZA744635B (en) 1975-08-27
CA1021778A (en) 1977-11-29
FR2239464B1 (de) 1978-04-14
CH573928A5 (de) 1976-03-31
DK138798C (de) 1979-04-09
US4010153A (en) 1977-03-01
GB1481219A (en) 1977-07-27
DK393274A (de) 1975-04-01
DE2436744A1 (de) 1975-02-27
JPS5041886A (de) 1975-04-16
NL7410256A (nl) 1975-02-03
NO137897C (no) 1978-05-16
BE818047A (fr) 1974-11-18
HU169180B (de) 1976-10-28
NO742739L (de) 1975-02-24
AR202224A1 (es) 1975-05-23
FI227474A (de) 1975-01-31
ATA567674A (de) 1976-10-15
IE39904B1 (en) 1979-01-31
SU528872A3 (ru) 1976-09-15
NO137897B (no) 1978-02-06

Similar Documents

Publication Publication Date Title
IL45289A (en) Process for the preperation of optically active 5-phenyl-13-dihydro-2h-1,4-benzodiazepin-2-ones and certain novel derivatives of this type
CA1027131A (en) Heterocyclic compounds and processes for their manufacture
HU172991B (hu) Sposob poluchenija novykh proizvodnykh bifosfino-ehtana i opticheski aktivnykh katalizatorov soderzhahhikh takie soedinenija
NL7413980A (nl) Werkwijze voor de bereiding van nieuwe n-(metho- xymethylfurylmethyl)-6,7-benzomorfanen en mor- finanen.
IL45158A0 (en) Piperazinyl-quinoxalines,derivatives and processes for their preparation
EG11698A (en) Process for the preparation of solid state ophthalmic medication
YU133774A (en) Process for the manufcture of oxazolidine derivatives
IL44892A (en) Process for the preparation of triazolo-isoindole derivatives and certain new compounds of this type
NO741607L (no) Fremgangsmåte for fremstilling av isocyanater.
IL45807A0 (en) Derivatives of 7alpha-methylester-4-ene-3alpha,17beta-diols
YU40105B (en) Process for the manufacture of n-arylsulfonyl-n'-(aza-3-bicycloalyl)-carbamides
ZA744425B (en) Dibenzoxepin derivatives and process for the preparation thereof
CA1025854A (en) Process for the purification of caprolactam
NO741044L (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive triaziner.
CA969943A (en) Process for the preparation of 1,3,4,5-tetrahydro-2h-1,4-benzodiazepin-2-one derivatives
CA1020553A (en) Processes for purification of derivatives of 1,4-benzodiazepin-2-one
IE39737L (en) Urea derivatives containing isocyanate groups
ZA742488B (en) Penicillins, processes for their preparation and their use as medicaments
CA1029034A (en) Ammoxidation process and catalyst
EG11352A (en) Process for the preparation of new-6-aza-3h-1,4-benzodiazepine
CH611599A5 (en) Process for the preparation of heterocyclic and carbocyclic diaryl compounds
ZA741172B (en) 1,4-dihydro-2-h-isoquinoline derivatives and process for their manufacture
IL44834A0 (en) 1-alkyl-2-(pyridylthiomethyl)-5-nitro-imidazoles and derivatives thereof and process for their manufacture
CH611124A5 (en) Selective herbicide comprising novel urea derivatives, and process for the preparation of the novel urea derivatives
CA985685A (en) Process for the preparation of 2-amino-4,5-dihydropyridine derivatives and compounds thereby produced