IL45289A - Process for the preperation of optically active 5-phenyl-13-dihydro-2h-1,4-benzodiazepin-2-ones and certain novel derivatives of this type - Google Patents
Process for the preperation of optically active 5-phenyl-13-dihydro-2h-1,4-benzodiazepin-2-ones and certain novel derivatives of this typeInfo
- Publication number
- IL45289A IL45289A IL45289A IL4528974A IL45289A IL 45289 A IL45289 A IL 45289A IL 45289 A IL45289 A IL 45289A IL 4528974 A IL4528974 A IL 4528974A IL 45289 A IL45289 A IL 45289A
- Authority
- IL
- Israel
- Prior art keywords
- preperation
- benzodiazepin
- dihydro
- ones
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1105673A CH573928A5 (de) | 1973-07-30 | 1973-07-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL45289A0 IL45289A0 (en) | 1974-10-22 |
| IL45289A true IL45289A (en) | 1979-12-30 |
Family
ID=4369623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL45289A IL45289A (en) | 1973-07-30 | 1974-07-17 | Process for the preperation of optically active 5-phenyl-13-dihydro-2h-1,4-benzodiazepin-2-ones and certain novel derivatives of this type |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4010153A (de) |
| JP (1) | JPS5041886A (de) |
| AR (1) | AR202224A1 (de) |
| AT (1) | AT337192B (de) |
| BE (1) | BE818047A (de) |
| CA (1) | CA1021778A (de) |
| CH (1) | CH573928A5 (de) |
| DE (1) | DE2436744A1 (de) |
| DK (1) | DK138798B (de) |
| ES (1) | ES428675A1 (de) |
| FI (1) | FI227474A (de) |
| FR (1) | FR2239464B1 (de) |
| GB (1) | GB1481219A (de) |
| HU (1) | HU169180B (de) |
| IE (1) | IE39904B1 (de) |
| IL (1) | IL45289A (de) |
| NL (1) | NL7410256A (de) |
| NO (1) | NO137897C (de) |
| SE (2) | SE7409708L (de) |
| SU (1) | SU528872A3 (de) |
| ZA (1) | ZA744635B (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1332410C (en) * | 1984-06-26 | 1994-10-11 | Roger M. Freidinger | Benzodiazepine analogs |
| US4820834A (en) * | 1984-06-26 | 1989-04-11 | Merck & Co., Inc. | Benzodiazepine analogs |
| HUE060259T2 (hu) | 2015-07-22 | 2023-02-28 | Enanta Pharm Inc | Benzodiazepin származékok mint RSV-gátlók |
| CN108699077B (zh) | 2016-01-15 | 2021-03-02 | 英安塔制药有限公司 | 作为rsv抑制剂的杂环化合物 |
| CA3065368A1 (en) | 2017-02-16 | 2018-08-23 | Enanta Pharmaceuticals, Inc. | Processes for the preparation of benzodiazepine derivatives |
| US10752598B2 (en) | 2017-06-07 | 2020-08-25 | Enanta Pharmaceuticals, Inc. | Aryldiazepine derivatives as RSV inhibitors |
| US11091501B2 (en) | 2017-06-30 | 2021-08-17 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as RSV inhibitors |
| US10851115B2 (en) | 2017-06-30 | 2020-12-01 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as RSV inhibitors |
| BR112020006334A2 (pt) | 2017-09-29 | 2020-09-24 | Enanta Pharmaceuticals, Inc. | combinação de agentes farmacêuticos como inibidores de rsv |
| WO2019094903A1 (en) * | 2017-11-13 | 2019-05-16 | Enanta Pharmaceuticals, Inc. | Processes for the resolution of benzodiazepin-2-one and benzoazepin-2-one derivatives |
| WO2019094920A1 (en) | 2017-11-13 | 2019-05-16 | Enanta Pharmaceuticals, Inc. | Azepin-2-one derivatives as rsv inhibitors |
| US10975094B2 (en) | 2018-04-11 | 2021-04-13 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as RSV inhibitors |
| KR20210138684A (ko) | 2019-03-18 | 2021-11-19 | 이난타 파마슈티칼스, 인코포레이티드 | Rsv 억제제로서의 벤조디아제핀 유도체 |
| US11179400B2 (en) | 2019-04-09 | 2021-11-23 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as RSV inhibitors |
| US11505558B1 (en) | 2019-10-04 | 2022-11-22 | Enanta Pharmaceuticals, Inc. | Antiviral heterocyclic compounds |
| UY39032A (es) | 2020-01-24 | 2021-07-30 | Enanta Pharm Inc | Compuestos heterocíclicos como agentes antivirales |
| US11534439B2 (en) | 2020-07-07 | 2022-12-27 | Enanta Pharmaceuticals, Inc. | Dihydroquinoxaline and dihydropyridopyrazine derivatives as RSV inhibitors |
| WO2022086840A1 (en) | 2020-10-19 | 2022-04-28 | Enanta Pharmaceuticals, Inc. | Heterocyclic compounds as anti-viral agents |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3371085A (en) * | 1959-12-10 | 1968-02-27 | Hoffmann La Roche | 5-aryl-3h-1,4-benzodiazepin-2(1h)-ones |
| JPS4426302Y1 (de) * | 1966-04-22 | 1969-11-05 |
-
1973
- 1973-07-30 CH CH1105673A patent/CH573928A5/xx not_active IP Right Cessation
-
1974
- 1974-07-09 AT AT567674A patent/AT337192B/de not_active IP Right Cessation
- 1974-07-11 GB GB30736/74A patent/GB1481219A/en not_active Expired
- 1974-07-12 IE IE1474/74A patent/IE39904B1/xx unknown
- 1974-07-17 IL IL45289A patent/IL45289A/xx unknown
- 1974-07-19 ZA ZA00744635A patent/ZA744635B/xx unknown
- 1974-07-22 DK DK393274AA patent/DK138798B/da unknown
- 1974-07-22 AR AR254832A patent/AR202224A1/es active
- 1974-07-24 BE BE146905A patent/BE818047A/xx unknown
- 1974-07-26 SU SU2049069A patent/SU528872A3/ru active
- 1974-07-26 CA CA205,715A patent/CA1021778A/en not_active Expired
- 1974-07-26 ES ES428675A patent/ES428675A1/es not_active Expired
- 1974-07-26 SE SE7409708A patent/SE7409708L/xx unknown
- 1974-07-29 US US05/492,912 patent/US4010153A/en not_active Expired - Lifetime
- 1974-07-29 FI FI2274/74A patent/FI227474A/fi unknown
- 1974-07-29 NO NO742739A patent/NO137897C/no unknown
- 1974-07-29 HU HUCO303A patent/HU169180B/hu unknown
- 1974-07-30 DE DE2436744A patent/DE2436744A1/de active Pending
- 1974-07-30 NL NL7410256A patent/NL7410256A/xx unknown
- 1974-07-30 FR FR7426475A patent/FR2239464B1/fr not_active Expired
- 1974-07-30 JP JP49087434A patent/JPS5041886A/ja active Pending
-
1975
- 1975-09-26 SE SE7510823A patent/SE7510823L/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL7410256A (nl) | 1975-02-03 |
| FR2239464A1 (de) | 1975-02-28 |
| IE39904B1 (en) | 1979-01-31 |
| FI227474A (de) | 1975-01-31 |
| DK393274A (de) | 1975-04-01 |
| SE7409708L (de) | 1975-01-31 |
| ATA567674A (de) | 1976-10-15 |
| GB1481219A (en) | 1977-07-27 |
| FR2239464B1 (de) | 1978-04-14 |
| BE818047A (fr) | 1974-11-18 |
| NO742739L (de) | 1975-02-24 |
| CA1021778A (en) | 1977-11-29 |
| DK138798B (da) | 1978-10-30 |
| US4010153A (en) | 1977-03-01 |
| ES428675A1 (es) | 1976-09-01 |
| SE7510823L (sv) | 1975-09-26 |
| DE2436744A1 (de) | 1975-02-27 |
| IL45289A0 (en) | 1974-10-22 |
| HU169180B (de) | 1976-10-28 |
| ZA744635B (en) | 1975-08-27 |
| IE39904L (en) | 1975-01-30 |
| NO137897C (no) | 1978-05-16 |
| AT337192B (de) | 1977-06-10 |
| CH573928A5 (de) | 1976-03-31 |
| SU528872A3 (ru) | 1976-09-15 |
| NO137897B (no) | 1978-02-06 |
| DK138798C (de) | 1979-04-09 |
| JPS5041886A (de) | 1975-04-16 |
| AR202224A1 (es) | 1975-05-23 |
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