IL40514A - Sulphamoyl-pyrimidines containing an asymmetric carbon atom and having a blood sugar lowering activity - Google Patents
Sulphamoyl-pyrimidines containing an asymmetric carbon atom and having a blood sugar lowering activityInfo
- Publication number
- IL40514A IL40514A IL40514A IL4051472A IL40514A IL 40514 A IL40514 A IL 40514A IL 40514 A IL40514 A IL 40514A IL 4051472 A IL4051472 A IL 4051472A IL 40514 A IL40514 A IL 40514A
- Authority
- IL
- Israel
- Prior art keywords
- carbon atoms
- general formula
- group
- meanings given
- given above
- Prior art date
Links
- 125000004432 carbon atom Chemical group C* 0.000 title claims 15
- 239000008280 blood Substances 0.000 title claims 6
- 210000004369 blood Anatomy 0.000 title claims 6
- 229910052799 carbon Inorganic materials 0.000 title claims 3
- WJJBIYLGJUVNJX-UHFFFAOYSA-N pyrimidine-2-sulfonamide Chemical class NS(=O)(=O)C1=NC=CC=N1 WJJBIYLGJUVNJX-UHFFFAOYSA-N 0.000 title 1
- 150000003839 salts Chemical class 0.000 claims 6
- 150000001875 compounds Chemical class 0.000 claims 5
- 206010012601 diabetes mellitus Diseases 0.000 claims 5
- 125000005843 halogen group Chemical group 0.000 claims 5
- 230000003287 optical effect Effects 0.000 claims 5
- 125000000217 alkyl group Chemical group 0.000 claims 4
- 239000002585 base Substances 0.000 claims 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 4
- 239000000825 pharmaceutical preparation Substances 0.000 claims 3
- 125000003545 alkoxy group Chemical group 0.000 claims 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 claims 2
- 125000001624 naphthyl group Chemical group 0.000 claims 2
- 125000004430 oxygen atom Chemical group O* 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical group CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 claims 1
- 125000003172 aldehyde group Chemical group 0.000 claims 1
- 229910052783 alkali metal Inorganic materials 0.000 claims 1
- -1 alkali metal salt Chemical class 0.000 claims 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 claims 1
- 150000001412 amines Chemical class 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 238000009833 condensation Methods 0.000 claims 1
- 230000005494 condensation Effects 0.000 claims 1
- 239000008298 dragée Substances 0.000 claims 1
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 claims 1
- 150000007529 inorganic bases Chemical class 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 150000007530 organic bases Chemical class 0.000 claims 1
- 229960003424 phenylacetic acid Drugs 0.000 claims 1
- 239000003279 phenylacetic acid Substances 0.000 claims 1
- 239000006187 pill Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/69—Benzenesulfonamido-pyrimidines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2150279A DE2150279C2 (de) | 1971-10-05 | 1971-10-05 | Blutzuckersenkende Sulfamoylpyrimidine mit asymmetrischem Kohlenstoffatom |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL40514A0 IL40514A0 (en) | 1972-12-29 |
| IL40514A true IL40514A (en) | 1976-12-31 |
Family
ID=5821847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL40514A IL40514A (en) | 1971-10-05 | 1972-10-05 | Sulphamoyl-pyrimidines containing an asymmetric carbon atom and having a blood sugar lowering activity |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS4844272A (de) |
| AT (1) | AT319952B (de) |
| CA (1) | CA977755A (de) |
| CH (1) | CH568982A5 (de) |
| DD (1) | DD103442A6 (de) |
| DE (1) | DE2150279C2 (de) |
| DK (1) | DK136034C (de) |
| GB (1) | GB1403264A (de) |
| IL (1) | IL40514A (de) |
| NL (1) | NL7213535A (de) |
| NO (1) | NO133138C (de) |
| SE (1) | SE385213B (de) |
| ZA (1) | ZA727126B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3119077A1 (de) * | 1981-05-14 | 1982-12-02 | Basf Ag, 6700 Ludwigshafen | Heterocyclische dihalogenacetmide, verfahren zu ihrer herstellung und herbizide mittel, die acetanilide als herbizide wirkstoffe und diese dihalogenacetamine als antagonistische mittel enthalten |
| PL2010493T3 (pl) * | 2006-04-12 | 2016-08-31 | Merck Sharp & Dohme | Pirydyloamidy jako antagoniści kanałów wapniowych typu t |
| RU2010120671A (ru) | 2007-10-24 | 2011-11-27 | Мерк Шарп Энд Домэ Корп. (Us) | Гетероциклические фениламидные антагонисты кальциевых каналов т-типа |
| TW201625588A (zh) * | 2014-11-05 | 2016-07-16 | 第一三共股份有限公司 | 環狀胺衍生物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1695855C3 (de) * | 1967-12-30 | 1979-07-12 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | 4-(5-Isobutyl-2-pyrimidinyl)-sulfonamidophenylessigsäure-(2-methoxy-5chloranilid) und dessen Salze mit physiologisch verträglichen Basen |
| JPS5516143A (en) * | 1978-07-18 | 1980-02-04 | Yoshihisa Horikoshi | Spindle |
-
1971
- 1971-10-05 DE DE2150279A patent/DE2150279C2/de not_active Expired
- 1971-10-19 NO NO713870A patent/NO133138C/no unknown
- 1971-10-22 DK DK515571A patent/DK136034C/da active
- 1971-10-27 SE SE7113647A patent/SE385213B/xx unknown
-
1972
- 1972-08-11 CH CH1193572A patent/CH568982A5/xx not_active IP Right Cessation
- 1972-10-02 DD DD165981A patent/DD103442A6/xx unknown
- 1972-10-03 AT AT846672A patent/AT319952B/de not_active IP Right Cessation
- 1972-10-05 IL IL40514A patent/IL40514A/en unknown
- 1972-10-05 JP JP47100227A patent/JPS4844272A/ja active Pending
- 1972-10-05 NL NL7213535A patent/NL7213535A/xx not_active Application Discontinuation
- 1972-10-05 ZA ZA727126A patent/ZA727126B/xx unknown
- 1972-10-05 GB GB4604672A patent/GB1403264A/en not_active Expired
- 1972-10-05 CA CA153,350A patent/CA977755A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DD103442A6 (de) | 1974-01-20 |
| AT319952B (de) | 1975-01-27 |
| DK136034B (da) | 1977-08-01 |
| NO133138B (de) | 1975-12-08 |
| JPS4844272A (de) | 1973-06-26 |
| GB1403264A (en) | 1975-08-28 |
| DE2150279A1 (de) | 1973-04-12 |
| IL40514A0 (en) | 1972-12-29 |
| NL7213535A (de) | 1973-04-09 |
| DK136034C (da) | 1978-01-23 |
| NO133138C (de) | 1976-03-17 |
| AU4735672A (en) | 1974-04-11 |
| CH568982A5 (de) | 1975-11-14 |
| SE385213B (sv) | 1976-06-14 |
| DE2150279C2 (de) | 1983-08-25 |
| ZA727126B (en) | 1973-06-27 |
| CA977755A (en) | 1975-11-11 |
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