GB1410275A - Phenoxycarboxylic acid derivatives their preparation and compositions containing them - Google Patents
Phenoxycarboxylic acid derivatives their preparation and compositions containing themInfo
- Publication number
- GB1410275A GB1410275A GB3430073A GB3430073A GB1410275A GB 1410275 A GB1410275 A GB 1410275A GB 3430073 A GB3430073 A GB 3430073A GB 3430073 A GB3430073 A GB 3430073A GB 1410275 A GB1410275 A GB 1410275A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- pharmaceutically acceptable
- acid derivatives
- july
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
- C07C59/70—Ethers of hydroxy-acetic acid, e.g. substitutes on the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1410275 Phenoxycarboxylic acid derivatives SUMITOMO CHEMICAL CO Ltd 18 July 1973 [30 July 1972] 34300/73 Addition to 1397697 Heading C2C Novel compounds of the Formula (I) wherein R 1 , R 2 and R 3 are each independently a hydrogen atom or a C 1-4 alkyl group, n is an integer of 4 to 6; and A is a hydrogen atom, a halogen atom, a C 1-4 alkyl, alkoxy, substituted or unsubstituted aryloxy, aralkoxy or keto alkoxy group, or a pharmaceutically acceptable salt thereof, may be obtained by reacting a phenol of the Formula (II) with (a) a carbonyl compound of the formula and chloroform in the presence of an alkali, or (b) a carboxylic acid derivative of the formula wherein X is a halogen atom or a hydroxyl group, and further, optionally, esterifying or hydrolyzing the resulting product. Pharmaceutical compositions, having cholesterol lowering activity, comprise a compound of Formula I above, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, preferably in forms suitable for oral administration.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP47073249A JPS4931651A (en) | 1972-07-20 | 1972-07-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1410275A true GB1410275A (en) | 1975-10-15 |
Family
ID=13512704
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB3430073A Expired GB1410275A (en) | 1972-07-20 | 1973-07-18 | Phenoxycarboxylic acid derivatives their preparation and compositions containing them |
Country Status (9)
Country | Link |
---|---|
JP (1) | JPS4931651A (en) |
AU (1) | AU5816173A (en) |
BE (1) | BE802539A (en) |
DD (1) | DD106357A5 (en) |
DE (1) | DE2336107A1 (en) |
FR (1) | FR2193592B1 (en) |
GB (1) | GB1410275A (en) |
HU (1) | HU166643B (en) |
ZA (1) | ZA734946B (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000010958A1 (en) * | 1998-08-24 | 2000-03-02 | Ligand Pharmaceuticals Incorporated | Vitamin d3 mimics |
WO2005037755A2 (en) * | 2003-10-14 | 2005-04-28 | X-Ceptor Therapeutics, Inc. | Bridged ring structures as pharmaceutical agents |
WO2005108337A2 (en) * | 2004-05-04 | 2005-11-17 | Acadia Pharmaceuticals Inc. | Compounds with activity at estrogen receptor |
WO2007056500A2 (en) * | 2005-11-08 | 2007-05-18 | Acadia Pharmaceuticals Inc. | Compounds with activity at estrogen receptors |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3716583A (en) * | 1969-04-16 | 1973-02-13 | Sumitomo Chemical Co | Phenoxy carboxylic acid derivative |
-
1972
- 1972-07-20 JP JP47073249A patent/JPS4931651A/ja active Pending
-
1973
- 1973-07-16 DE DE19732336107 patent/DE2336107A1/en active Pending
- 1973-07-17 AU AU58161/73A patent/AU5816173A/en not_active Expired
- 1973-07-18 DD DD172344A patent/DD106357A5/xx unknown
- 1973-07-18 GB GB3430073A patent/GB1410275A/en not_active Expired
- 1973-07-18 FR FR7326273A patent/FR2193592B1/fr not_active Expired
- 1973-07-19 ZA ZA734946A patent/ZA734946B/en unknown
- 1973-07-19 BE BE133639A patent/BE802539A/en unknown
- 1973-07-19 HU HUSU826A patent/HU166643B/hu unknown
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000010958A1 (en) * | 1998-08-24 | 2000-03-02 | Ligand Pharmaceuticals Incorporated | Vitamin d3 mimics |
WO2005037755A2 (en) * | 2003-10-14 | 2005-04-28 | X-Ceptor Therapeutics, Inc. | Bridged ring structures as pharmaceutical agents |
WO2005037755A3 (en) * | 2003-10-14 | 2005-08-18 | X Ceptor Therapeutics Inc | Bridged ring structures as pharmaceutical agents |
US7863298B2 (en) | 2003-10-14 | 2011-01-04 | Exelixis, Inc. | Bridged ring structures as pharmaceutical agents |
AU2004282162B2 (en) * | 2003-10-14 | 2012-01-19 | X-Ceptor Therapeutics, Inc. | Bridged ring structures as pharmaceutical agents |
WO2005108337A2 (en) * | 2004-05-04 | 2005-11-17 | Acadia Pharmaceuticals Inc. | Compounds with activity at estrogen receptor |
WO2005108337A3 (en) * | 2004-05-04 | 2005-12-22 | Acadia Pharm Inc | Compounds with activity at estrogen receptor |
US7825265B2 (en) | 2004-05-04 | 2010-11-02 | Acadia Pharmaceuticals Inc. | Compounds with activity at estrogen receptors |
US8822548B2 (en) | 2004-05-04 | 2014-09-02 | Acadia Pharmaceuticals Inc. | Compounds with activity at estrogen receptors |
WO2007056500A2 (en) * | 2005-11-08 | 2007-05-18 | Acadia Pharmaceuticals Inc. | Compounds with activity at estrogen receptors |
WO2007056500A3 (en) * | 2005-11-08 | 2007-09-20 | Acadia Pharm Inc | Compounds with activity at estrogen receptors |
Also Published As
Publication number | Publication date |
---|---|
ZA734946B (en) | 1974-07-31 |
AU5816173A (en) | 1975-01-23 |
FR2193592A1 (en) | 1974-02-22 |
JPS4931651A (en) | 1974-03-22 |
HU166643B (en) | 1975-04-28 |
DD106357A5 (en) | 1974-06-12 |
DE2336107A1 (en) | 1974-01-31 |
BE802539A (en) | 1973-11-16 |
FR2193592B1 (en) | 1976-10-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
CSNS | Application of which complete specification have been accepted and published, but patent is not sealed |