IL40494A - Pleuromutilins,their production and pharmaceutical compositions containing them - Google Patents

Pleuromutilins,their production and pharmaceutical compositions containing them

Info

Publication number
IL40494A
IL40494A IL40494A IL4049472A IL40494A IL 40494 A IL40494 A IL 40494A IL 40494 A IL40494 A IL 40494A IL 4049472 A IL4049472 A IL 4049472A IL 40494 A IL40494 A IL 40494A
Authority
IL
Israel
Prior art keywords
formula
nitrogen atom
group
alkyl
compound
Prior art date
Application number
IL40494A
Other languages
English (en)
Other versions
IL40494A0 (en
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27509313&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL40494(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from CH1445071A external-priority patent/CH560180A5/de
Priority claimed from CH1445171A external-priority patent/CH559719A5/de
Priority claimed from CH774072A external-priority patent/CH575375A5/de
Priority claimed from CH773972A external-priority patent/CH568272A5/de
Priority claimed from CH773872A external-priority patent/CH572893A5/xx
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IL40494A0 publication Critical patent/IL40494A0/xx
Publication of IL40494A publication Critical patent/IL40494A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL40494A 1971-10-05 1972-10-04 Pleuromutilins,their production and pharmaceutical compositions containing them IL40494A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CH1445071A CH560180A5 (en) 1971-10-05 1971-10-05 Pleuromutilin derivs - with antibacterial activity
CH1445171A CH559719A5 (en) 1971-10-05 1971-10-05 Pleuromutilin derivs - with antibacterial activity
CH774072A CH575375A5 (fr) 1972-05-25 1972-05-25
CH773972A CH568272A5 (en) 1972-05-25 1972-05-25 (Para-substd phenoxy- or phenylthio-acetoxy)-pleuromutilin deriv - prepd by reacting para-hydroxy or-mercapto cpds with e.g. aminoalkyl halides
CH773872A CH572893A5 (en) 1972-05-25 1972-05-25 Pleuromutilin derivs - with antibacterial activity

Publications (2)

Publication Number Publication Date
IL40494A0 IL40494A0 (en) 1972-12-29
IL40494A true IL40494A (en) 1976-01-30

Family

ID=27509313

Family Applications (1)

Application Number Title Priority Date Filing Date
IL40494A IL40494A (en) 1971-10-05 1972-10-04 Pleuromutilins,their production and pharmaceutical compositions containing them

Country Status (20)

Country Link
US (1) US4278674A (fr)
JP (1) JPS577147B2 (fr)
BE (1) BE789629A (fr)
BG (2) BG20773A3 (fr)
CA (1) CA979447A (fr)
DD (1) DD100706A5 (fr)
DE (2) DE2248237C2 (fr)
DK (1) DK139720B (fr)
FI (1) FI58635C (fr)
FR (1) FR2157828B1 (fr)
GB (1) GB1410505A (fr)
HU (1) HU168436B (fr)
IE (1) IE37699B1 (fr)
IL (1) IL40494A (fr)
NL (1) NL177403C (fr)
NO (3) NO136459C (fr)
OA (1) OA04192A (fr)
PH (1) PH11870A (fr)
RO (2) RO67478A (fr)
SE (3) SE398348B (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3987194A (en) * 1975-05-12 1976-10-19 E. R. Squibb & Sons, Inc. Use of pleuromutilin derivatives for the treatment of swine dysentery
FR2428030A1 (fr) * 1978-06-06 1980-01-04 Sandoz Sa Procede de preparation de derives de la pleuromutiline
JPS56168463A (en) * 1980-05-30 1981-12-24 Iwao Koyama Telephone set
LU82738A1 (fr) * 1980-08-29 1982-05-10 Continental Pharma Derives d'aminothiols,leur preparation et utilisation ainsi que compositions contenant ces derives
JPS60121870A (ja) * 1983-12-06 1985-06-29 Matsushita Electric Ind Co Ltd インタ−ホン装置
JPS62137952A (ja) * 1985-12-12 1987-06-20 Sakuragi Kunio 電話機
JPH0418190Y2 (fr) * 1986-09-19 1992-04-23
JPH01105238U (fr) * 1988-01-05 1989-07-14
IL124912A0 (en) * 1996-01-03 1999-01-26 Smithkline Beecham Plc Carbamoyloxy derivatives of mutiline and their use as antibacterials
FR2746012B1 (fr) * 1996-03-13 1998-05-22 Utilisation de la tiamuline pour la preparation d'un medicament comme agent de reversion de la multichimioresistance cancereuse
UY25225A1 (es) * 1997-10-29 2000-12-29 Smithkline Beecham Plc Derivados de pleuromutilina utiles como agentes antimicrobianos
WO2000027790A1 (fr) * 1998-11-11 2000-05-18 Smithkline Beecham P.L.C. Composes a base de mutiline
AU3036200A (en) * 1998-12-18 2000-07-12 Smithkline Beecham Plc Mutilin 14-ester derivatives having antibacterial activity
GB9912657D0 (en) * 1999-06-01 1999-07-28 Smithkline Beecham Plc Novel compounds
GB9918037D0 (en) 1999-07-30 1999-09-29 Biochemie Gmbh Organic compounds
GB0017031D0 (en) * 2000-07-11 2000-08-30 Biochemie Gmbh Antimicrobials
PE20020676A1 (es) * 2000-09-13 2002-08-27 Biochemie Gmbh Compuestos de mutilina como antibacterianos
GB0207495D0 (en) * 2002-03-28 2002-05-08 Biochemie Gmbh Organic compounds
GB0308114D0 (en) * 2003-04-08 2003-05-14 Glaxo Group Ltd Novel compounds
EP1663220B1 (fr) * 2003-09-03 2009-12-02 Glaxo Group Limited Nouveau procede pour la fabrication de derives de la pleuromutiline
GB0504314D0 (en) * 2005-03-02 2005-04-06 Glaxo Group Ltd Novel polymorph
EP1860943A4 (fr) * 2005-03-10 2008-06-18 Smithkline Beecham Corp Nouveau procede
GB0513058D0 (en) * 2005-06-27 2005-08-03 Sandoz Ag Organic compounds
EP1808431A1 (fr) * 2006-01-16 2007-07-18 Nabriva Therapeutics Forschungs GmbH Dérivés de mutiline et leur utilisation en tant que composé pharmaceutique
WO2008117796A1 (fr) * 2007-03-28 2008-10-02 Dainippon Sumitomo Pharma Co., Ltd. Nouveaux dérivés de mutiline
CN101434567B (zh) * 2008-12-19 2012-10-24 李扬 一种二乙氨基乙硫醇的制备方法
CN103709115A (zh) * 2012-10-09 2014-04-09 山东亨利医药科技有限责任公司 截短侧耳素类抗生素衍生物
WO2014087298A1 (fr) 2012-12-03 2014-06-12 Pfizer Inc. Nouveaux modulateurs androgéniques sélectifs
CN104447449B (zh) * 2014-12-30 2016-06-15 陕西师范大学 一锅法合成泰妙菌素的方法
CN110981769B (zh) * 2019-12-19 2022-02-18 江苏威凌生化科技有限公司 一种制备泰秒菌素的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT301753B (de) * 1969-07-25 1972-09-25 Biochemie Gmbh Verfahren zur Herstellung neuer Pleuromutilin-Derivate
US4107164A (en) * 1971-10-05 1978-08-15 Sandoz Ltd. Certain pleuromulilin ester derivatives
US4032530A (en) * 1971-10-05 1977-06-28 Sandoz Ltd. Certain pleuromutilins
US3919290A (en) * 1972-10-03 1975-11-11 Sandoz Ltd Substituted 14-desoxy-mutilins

Also Published As

Publication number Publication date
SE7509456L (sv) 1975-08-26
IE37699L (en) 1973-04-05
DK139720B (da) 1979-04-02
NO136837C (no) 1977-11-16
DE2248237C2 (de) 1983-02-10
NL177403B (nl) 1985-04-16
SE424074B (sv) 1982-06-28
SE7509457L (sv) 1975-08-26
HU168436B (fr) 1976-04-28
GB1410505A (en) 1975-10-15
OA04192A (fr) 1979-12-31
DE2248237A1 (de) 1973-04-12
DD100706A5 (fr) 1973-10-05
NO136459C (no) 1977-09-07
SE419984B (sv) 1981-09-07
JPS4844244A (fr) 1973-06-26
NL177403C (nl) 1985-09-16
DK139720C (fr) 1979-10-01
FR2157828A1 (fr) 1973-06-08
JPS577147B2 (fr) 1982-02-09
SE398348B (sv) 1977-12-19
FI58635B (fi) 1980-11-28
CA979447A (en) 1975-12-09
NO137440B (no) 1977-11-21
RO67479A (fr) 1981-06-21
PH11870A (en) 1978-08-04
IL40494A0 (en) 1972-12-29
FI58635C (fi) 1981-03-10
NO137440C (no) 1978-03-01
DE2265666C2 (de) 1983-02-03
NL7213254A (fr) 1973-04-09
NO136837B (no) 1977-08-08
FR2157828B1 (fr) 1975-11-28
BG20773A3 (fr) 1975-12-20
BE789629A (fr) 1973-04-03
US4278674A (en) 1981-07-14
RO67478A (fr) 1980-03-15
NO136459B (fr) 1977-05-31
BG21386A3 (fr) 1976-05-20
IE37699B1 (en) 1977-09-28

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