IL39528A - History of 4,5-diaryl-2-oxazolyl and 2-thiazolyl-alkanoic mercanoic acid - Google Patents
History of 4,5-diaryl-2-oxazolyl and 2-thiazolyl-alkanoic mercanoic acidInfo
- Publication number
- IL39528A IL39528A IL39528A IL3952872A IL39528A IL 39528 A IL39528 A IL 39528A IL 39528 A IL39528 A IL 39528A IL 3952872 A IL3952872 A IL 3952872A IL 39528 A IL39528 A IL 39528A
- Authority
- IL
- Israel
- Prior art keywords
- acid
- mercapto
- oxazolyl
- ethyl ester
- add
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/36—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/46—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2129012A DE2129012A1 (de) | 1971-06-11 | 1971-06-11 | Azol-derivate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL39528A0 IL39528A0 (en) | 1972-07-26 |
| IL39528A true IL39528A (en) | 1976-08-31 |
Family
ID=5810494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL39528A IL39528A (en) | 1971-06-11 | 1972-05-25 | History of 4,5-diaryl-2-oxazolyl and 2-thiazolyl-alkanoic mercanoic acid |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US3933840A (hu) |
| JP (1) | JPS5728705B1 (hu) |
| AT (6) | AT328440B (hu) |
| AU (1) | AU462556B2 (hu) |
| BE (1) | BE784682A (hu) |
| BR (1) | BR7203714D0 (hu) |
| CA (1) | CA1008863A (hu) |
| CH (6) | CH590856A5 (hu) |
| CS (6) | CS167984B2 (hu) |
| DD (1) | DD97206A5 (hu) |
| DE (1) | DE2129012A1 (hu) |
| ES (2) | ES403741A1 (hu) |
| FR (1) | FR2140632B1 (hu) |
| GB (1) | GB1331408A (hu) |
| HU (1) | HU166271B (hu) |
| IL (1) | IL39528A (hu) |
| NL (1) | NL7207784A (hu) |
| PL (1) | PL79513B1 (hu) |
| RO (1) | RO60483A (hu) |
| SE (1) | SE381467B (hu) |
| ZA (1) | ZA723502B (hu) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2129012A1 (de) * | 1971-06-11 | 1973-01-04 | Merck Patent Gmbh | Azol-derivate |
| US4089865A (en) * | 1971-10-27 | 1978-05-16 | Syntex (U.S.A.) Inc. | Certain thiazole compounds |
| GB1507032A (en) * | 1974-08-06 | 1978-04-12 | Serono Lab | 2-thiol-4,5-diphenyloxazole s-derivatives |
| DE2549998A1 (de) * | 1975-11-07 | 1977-05-12 | Merck Patent Gmbh | Mittel zur hemmung der thrombozytenaggregation |
| IT1099996B (it) * | 1978-10-17 | 1985-09-28 | Anic Spa | Derivati del 4,5-difenil-ossazolo 2-ammino o 2-tio sostituiti e procedimento per il loro ottenimento |
| DE3060330D1 (en) * | 1979-04-06 | 1982-06-09 | Bayer Ag | Azolyloxy-acetamides, process for their preparation and their use as herbicides |
| DE2946524A1 (de) * | 1979-11-17 | 1981-06-11 | Bayer Ag, 5090 Leverkusen | Azolyloxy-carbonsaeure-n-oxy-amide, verfahren zu ihrer herstellung und ihre verwendung als herbizide |
| US4451471A (en) * | 1981-03-18 | 1984-05-29 | Ciba-Geigy Corporation | Certain 2,4,5-tri-substituted thiazoles, pharmaceutical compositions containing same and methods of using same |
| DE3336846A1 (de) * | 1983-10-11 | 1985-04-25 | Bayer Ag, 5090 Leverkusen | Neue 2-mercaptothiazolderivate, verfahren zu deren herstellung sowie die verwendung von 2-mercaptothiazolderivaten in arzneimitteln |
| DE3508665A1 (de) * | 1985-03-12 | 1986-09-18 | Hoechst Ag, 6230 Frankfurt | Heterocyclische sulfide und ihre anwendung als immunmodulatoren |
| GB8610432D0 (en) * | 1986-04-29 | 1986-06-04 | Akzo Nv | Amino-thiazole & oxazole derivatives |
| USRE34242E (en) * | 1986-04-29 | 1993-05-04 | Akzo N.V. | Amino-oxazole compounds having dopaminergic activity |
| DE3807232A1 (de) * | 1988-03-05 | 1989-09-14 | Bayer Ag | Substituierte acrylsaeureester |
| JPH02145524A (ja) * | 1988-11-29 | 1990-06-05 | Katsumi Nagata | 木酢液より得られる医薬品原料の製造方法 |
| JP2785879B2 (ja) * | 1989-05-31 | 1998-08-13 | ジ・アップジョン・カンパニー | 治療学的に有用な２―アミノテトラリン誘導体 |
| US5545755A (en) * | 1989-05-31 | 1996-08-13 | The Upjohn Company | Therapeutically useful 2-aminotetralin derivatives |
| NZ236474A (en) * | 1989-12-20 | 1993-07-27 | Bristol Myers Squibb Co | 4,5-diphenyl-2-oxazole octanoic, nonanoic and decanoic acid and ester derivatives, preparation and pharmaceutical compositions thereof |
| US5274117A (en) * | 1990-01-22 | 1993-12-28 | Hoechst-Roussel Pharmaceuticals, Inc. | Process for the enantioselective synthesis of intermediates used in the preparation of physostigmine |
| US5840915A (en) * | 1990-01-22 | 1998-11-24 | Hoechst Marion Roussel, Inc. | Process for the enatioselective synthesis of intermediates used |
| FR2663331B1 (fr) * | 1990-06-14 | 1994-05-06 | Bellon Laboratoires | Nouveaux derives de l'oxazole, leur preparation et les compositions pharmaceutiques qui les contiennent. |
| US5380738A (en) * | 1993-05-21 | 1995-01-10 | Monsanto Company | 2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents |
| WO1996038418A1 (en) | 1995-06-02 | 1996-12-05 | G.D. Searle & Co. | Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors |
| US6515014B2 (en) | 1995-06-02 | 2003-02-04 | G. D. Searle & Co. | Thiophene substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors |
| US6512121B2 (en) | 1998-09-14 | 2003-01-28 | G.D. Searle & Co. | Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors |
| US6677364B2 (en) | 1998-04-20 | 2004-01-13 | G.D. Searle & Co. | Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors |
| WO2000015229A1 (en) | 1998-09-17 | 2000-03-23 | Bristol-Myers Squibb Company | METHOD FOR TREATING DIABETES EMPLOYING AN aP2 INHIBITOR AND COMBINATION |
| US7358254B2 (en) | 2001-07-13 | 2008-04-15 | Bristol-Myers Squibb Company | Method for treating atherosclerosis employing an aP2 inhibitor and combination |
| US7390824B1 (en) | 1999-09-07 | 2008-06-24 | Bristol-Myers Squibb Company | Method for treating diabetes employing an aP2 inhibitor and combination |
| US20030105144A1 (en) | 2001-04-17 | 2003-06-05 | Ping Gao | Stabilized oral pharmaceutical composition |
| US7329401B2 (en) * | 2002-04-15 | 2008-02-12 | The Regents Of The University Of California | Cyclooxygenase-2 selective agents useful as imaging probes and related methods |
| TW200505446A (en) * | 2003-01-17 | 2005-02-16 | Fuj Isawa Pharmaceutical Co Ltd | Inhibitor of cox |
| WO2023143741A1 (de) * | 2022-01-28 | 2023-08-03 | Symrise Ag | Neue kühlstoffe und zubereitungen, die diese enthalten |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2513923A (en) * | 1947-11-10 | 1950-07-04 | Ilford Ltd | Dyestuffs from s-(thiazolyl-2)-thioglycollic acid and method for preparing same |
| US3578671A (en) * | 1967-11-06 | 1971-05-11 | Wyeth John & Brother Ltd | Oxazoles |
| DE2129012A1 (de) * | 1971-06-11 | 1973-01-04 | Merck Patent Gmbh | Azol-derivate |
-
1971
- 1971-06-11 DE DE2129012A patent/DE2129012A1/de not_active Withdrawn
-
1972
- 1972-05-22 ZA ZA723502A patent/ZA723502B/xx unknown
- 1972-05-23 GB GB2419572A patent/GB1331408A/en not_active Expired
- 1972-05-25 IL IL39528A patent/IL39528A/en unknown
- 1972-05-25 RO RO71023A patent/RO60483A/ro unknown
- 1972-05-29 CS CS3691A patent/CS167984B2/cs unknown
- 1972-05-29 CS CS4415*A patent/CS167987B2/cs unknown
- 1972-05-29 CS CS4413*A patent/CS167985B2/cs unknown
- 1972-05-29 CS CS4414*A patent/CS167986B2/cs unknown
- 1972-05-29 CS CS4416*A patent/CS167988B2/cs unknown
- 1972-05-29 CS CS4417*A patent/CS167989B2/cs unknown
- 1972-05-29 AU AU42850/72A patent/AU462556B2/en not_active Expired
- 1972-05-31 CH CH28676A patent/CH590856A5/xx not_active IP Right Cessation
- 1972-05-31 CH CH28876A patent/CH584702A5/xx not_active IP Right Cessation
- 1972-05-31 CH CH28776A patent/CH584701A5/xx not_active IP Right Cessation
- 1972-05-31 CH CH28976A patent/CH584210A5/xx not_active IP Right Cessation
- 1972-05-31 CH CH806272A patent/CH584700A5/xx not_active IP Right Cessation
- 1972-05-31 CH CH28576A patent/CH585213A5/xx not_active IP Right Cessation
- 1972-06-05 SE SE7207357A patent/SE381467B/xx unknown
- 1972-06-06 US US05/260,307 patent/US3933840A/en not_active Expired - Lifetime
- 1972-06-07 AT AT489572A patent/AT328440B/de not_active IP Right Cessation
- 1972-06-07 AT AT136474*1A patent/AT323158B/de not_active IP Right Cessation
- 1972-06-08 NL NL7207784A patent/NL7207784A/xx not_active Application Discontinuation
- 1972-06-09 CA CA144,331A patent/CA1008863A/en not_active Expired
- 1972-06-09 HU HUME1505A patent/HU166271B/hu unknown
- 1972-06-09 BE BE784682A patent/BE784682A/xx unknown
- 1972-06-09 PL PL1972155917A patent/PL79513B1/pl unknown
- 1972-06-09 DD DD163592A patent/DD97206A5/xx unknown
- 1972-06-09 BR BR3714/72A patent/BR7203714D0/pt unknown
- 1972-06-09 FR FR7220858A patent/FR2140632B1/fr not_active Expired
- 1972-06-10 ES ES403741A patent/ES403741A1/es not_active Expired
- 1972-06-12 JP JP5775772A patent/JPS5728705B1/ja active Pending
-
1974
- 1974-02-20 AT AT136574*1A patent/AT327889B/de active
- 1974-02-20 AT AT136674*1A patent/AT327890B/de active
- 1974-02-20 AT AT136774*1A patent/AT327891B/de not_active IP Right Cessation
- 1974-02-20 AT AT136874*1A patent/AT327892B/de active
-
1975
- 1975-07-15 ES ES439448A patent/ES439448A1/es not_active Expired
- 1975-10-21 US US05/624,447 patent/US4051250A/en not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL39528A (en) | History of 4,5-diaryl-2-oxazolyl and 2-thiazolyl-alkanoic mercanoic acid | |
| IE41724B1 (en) | Diphenylsulphoxide derivatives | |
| EA010633B1 (ru) | Новые бензальдоксимы, способ получения бензальдоксимов и его применение | |
| GB1563842A (en) | Phenyl-acetic acids and derivatives thereof | |
| SU425394A3 (ru) | Способ получения производных фенилуксусной кислоты | |
| JPH06345724A (ja) | シアノ化合物およびその製造方法 | |
| PL84493B1 (hu) | ||
| US3669956A (en) | 4-substitutedamino-phenylacetic acids and derivatives thereof | |
| DK171274B1 (da) | Fremgangsmåde til fremstilling af 3,3'-azo-bis-(6-hydroxy-benzoesyre) samt azobenzener som mellemprodukter dertil | |
| US3976641A (en) | Cephalosporin intermediates and process therefor | |
| US4267343A (en) | Process for the manufacture of 2,5-bis-(benzoxazolyl)-thiophene compounds | |
| JP3493288B2 (ja) | ２−（１０，１１−ジヒドロ−１０−オキソジベンゾ［ｂ，ｆ］チエピン−２−イル）プロピオン酸の製造方法、及びその中間体化合物 | |
| CA2483482A1 (en) | Process for the preparation of 4-methyl-thiazole-5-carbaldehyde intermediate | |
| CA1130307A (en) | Pharmaceutical n-(indanon-7-yl) oxaminic acid derivatives | |
| GB1562943A (en) | Pyrazole derivatives and their manufacture and use | |
| US3493584A (en) | 4-substituted amino-5-sulfamoylbenzoic acid derivatives and preparation | |
| AU731262B2 (en) | 9,10-diazatricyclo{4.2.1.12,5}decane and 2,7-diazatricyclo{4.4.0.03,8}decane derivatives having analgesic activity | |
| BURGER et al. | Some Derivatives of Homoanisic Acid | |
| JPS6242962A (ja) | アジドスルホニル安息香酸の製造法 | |
| US3361789A (en) | Hypocholesterolemic agents | |
| JPS5944312B2 (ja) | インダゾ−ル誘導体の製法 | |
| CA2627325A1 (en) | 3-hydroxymethylbenzo[b]thiophene derivative and method for producing same | |
| US3201475A (en) | Bisglyoxalyldiphenyl derivatives | |
| Guravaiah et al. | Facile polyethylene glycol (PEG-400) promoted synthesis of some new heteryl (E)-styryl sulfones | |
| PL80177B1 (hu) |