IL35729A - 2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines,their preparation and pharmaceutical compositions containing them - Google Patents

2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL35729A
IL35729A IL35729A IL3572970A IL35729A IL 35729 A IL35729 A IL 35729A IL 35729 A IL35729 A IL 35729A IL 3572970 A IL3572970 A IL 3572970A IL 35729 A IL35729 A IL 35729A
Authority
IL
Israel
Prior art keywords
thieno
pyrimidines
furyl
nitro
preparation
Prior art date
Application number
IL35729A
Other languages
English (en)
Other versions
IL35729A0 (en
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19691959403 external-priority patent/DE1959403A1/de
Priority claimed from DE19702050814 external-priority patent/DE2050814A1/de
Priority claimed from DE19702050815 external-priority patent/DE2050815A1/de
Priority claimed from DE19702050816 external-priority patent/DE2050816A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of IL35729A0 publication Critical patent/IL35729A0/xx
Publication of IL35729A publication Critical patent/IL35729A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL35729A 1969-11-26 1970-11-26 2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines,their preparation and pharmaceutical compositions containing them IL35729A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19691959403 DE1959403A1 (de) 1969-11-26 1969-11-26 Neue 2-(5-Nitro-2-furyl)-thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
DE19702050814 DE2050814A1 (de) 1970-10-16 1970-10-16 Neue Verfahren zur Herstellung von 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidinen
DE19702050815 DE2050815A1 (de) 1970-10-16 1970-10-16 Neue 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine
DE19702050816 DE2050816A1 (de) 1970-10-16 1970-10-16 Neue 2-(Nitro-2-furyl>thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine

Publications (2)

Publication Number Publication Date
IL35729A0 IL35729A0 (en) 1971-01-28
IL35729A true IL35729A (en) 1974-01-14

Family

ID=27430978

Family Applications (1)

Application Number Title Priority Date Filing Date
IL35729A IL35729A (en) 1969-11-26 1970-11-26 2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines,their preparation and pharmaceutical compositions containing them

Country Status (13)

Country Link
US (1) US3661908A (nl)
BE (1) BE759493A (nl)
BG (2) BG17799A3 (nl)
CA (1) CA926865A (nl)
CH (3) CH567029A5 (nl)
DK (1) DK128781B (nl)
FR (1) FR2073416B1 (nl)
GB (1) GB1321316A (nl)
IE (1) IE34765B1 (nl)
IL (1) IL35729A (nl)
NL (1) NL7017210A (nl)
NO (1) NO129954B (nl)
SE (1) SE377938B (nl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932642A (en) * 1971-04-10 1976-01-13 Boehringer Ingelheim Gmbh Biocidal compositions containing a 2- (5'-nitro-2'-furyl)-thieno(2,3-d) pyrimidine and methods of use
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
US20040138238A1 (en) * 2002-08-08 2004-07-15 Dhanoa Dale S. Substituted aminopyrimidine compounds as neurokinin antagonists
GB0423653D0 (en) * 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
CL2007001166A1 (es) 2006-04-26 2008-01-25 Piramed Ltd Compuestos derivados de pirimidina condensada, inhibidores de pi3-quinasa; procesos para preparar los compuestos; composicion farmaceutica que los comprende; uso de los compuestos en la preparacion de medicamentos; proceso para preparar la composicion farmaceutica; y kit que incluye a la composicion farmaceutica
NZ572812A (en) * 2006-04-26 2010-09-30 Hoffmann La Roche THIENO [3, 2-D] PYRIMIDINE Indazole DERIVATIVE USEFUL AS PI3K INHIBITOR
ATE532788T1 (de) * 2006-04-26 2011-11-15 Hoffmann La Roche Pharmazeutische verbindungen
EP2114950B1 (en) * 2006-12-07 2016-03-09 Genentech, Inc. Phosphoinositide 3-kinase inhibitor compounds and methods of use
ES2544082T3 (es) * 2006-12-07 2015-08-27 F. Hoffmann-La Roche Ag Compuestos inhibidores de fosfoinosítido 3-quinasa y métodos de uso
CN101679456B (zh) * 2007-06-12 2012-09-05 霍夫曼-拉罗奇有限公司 噻唑并嘧啶类和它们作为磷脂酰肌醇3-激酶的抑制剂的应用
EP2207781B1 (en) * 2007-09-24 2012-11-28 Genentech, Inc. Thiazolopyrimidine p13k inhibitor compounds and methods of use
EP2214675B1 (en) 2007-10-25 2013-11-20 Genentech, Inc. Process for making thienopyrimidine compounds
GB0721095D0 (en) * 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
CN102369011A (zh) 2009-03-12 2012-03-07 健泰科生物技术公司 用于治疗造血恶性肿瘤的磷酸肌醇3-激酶抑制剂化合物与化学治疗剂的组合
US8158625B2 (en) * 2009-05-27 2012-04-17 Genentech, Inc. Bicyclic indole-pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of use
JP5781066B2 (ja) 2009-05-27 2015-09-16 ジェネンテック， インコーポレイテッド ｐ１１０δに対して選択的な二環式ピリミジンＰＩ３Ｋ阻害剤化合物及び使用方法
MX345155B (es) * 2009-10-12 2017-01-18 F Hoffmann-La Roche Ag * Combinaciones de un inhibidor de pi3k y un inhibidor de mek.
EP2558864A1 (en) 2010-04-16 2013-02-20 Genentech, Inc. Fox03a as predictive biomarker for pi3k/akt kinase pathway inhibitor efficacy
US20140004209A1 (en) 2010-12-22 2014-01-02 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
CN105247072B (zh) 2013-02-25 2019-10-15 基因泰克公司 检测和治疗抗药性akt突变体的方法和组合物

Also Published As

Publication number Publication date
US3661908A (en) 1972-05-09
BE759493A (fr) 1971-05-25
BG17800A3 (bg) 1973-12-25
SE377938B (nl) 1975-08-04
CH568324A5 (nl) 1975-10-31
IL35729A0 (en) 1971-01-28
FR2073416B1 (nl) 1975-04-18
CH567029A5 (nl) 1975-09-30
NL7017210A (nl) 1971-05-28
IE34765B1 (en) 1975-08-06
GB1321316A (en) 1973-06-27
FR2073416A1 (nl) 1971-10-01
IE34765L (en) 1971-05-26
CH559210A5 (nl) 1975-02-28
DK128781B (da) 1974-07-01
CA926865A (en) 1973-05-22
BG17799A3 (bg) 1973-12-25
NO129954B (nl) 1974-06-17

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