IL35729A - 2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines,their preparation and pharmaceutical compositions containing them - Google Patents
2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL35729A IL35729A IL35729A IL3572970A IL35729A IL 35729 A IL35729 A IL 35729A IL 35729 A IL35729 A IL 35729A IL 3572970 A IL3572970 A IL 3572970A IL 35729 A IL35729 A IL 35729A
- Authority
- IL
- Israel
- Prior art keywords
- thieno
- pyrimidines
- furyl
- nitro
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19691959403 DE1959403A1 (de) | 1969-11-26 | 1969-11-26 | Neue 2-(5-Nitro-2-furyl)-thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung |
DE19702050814 DE2050814A1 (de) | 1970-10-16 | 1970-10-16 | Neue Verfahren zur Herstellung von 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidinen |
DE19702050815 DE2050815A1 (de) | 1970-10-16 | 1970-10-16 | Neue 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine |
DE19702050816 DE2050816A1 (de) | 1970-10-16 | 1970-10-16 | Neue 2-(Nitro-2-furyl>thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine |
Publications (2)
Publication Number | Publication Date |
---|---|
IL35729A0 IL35729A0 (en) | 1971-01-28 |
IL35729A true IL35729A (en) | 1974-01-14 |
Family
ID=27430978
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL35729A IL35729A (en) | 1969-11-26 | 1970-11-26 | 2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines,their preparation and pharmaceutical compositions containing them |
Country Status (13)
Country | Link |
---|---|
US (1) | US3661908A (nl) |
BE (1) | BE759493A (nl) |
BG (2) | BG17799A3 (nl) |
CA (1) | CA926865A (nl) |
CH (3) | CH567029A5 (nl) |
DK (1) | DK128781B (nl) |
FR (1) | FR2073416B1 (nl) |
GB (1) | GB1321316A (nl) |
IE (1) | IE34765B1 (nl) |
IL (1) | IL35729A (nl) |
NL (1) | NL7017210A (nl) |
NO (1) | NO129954B (nl) |
SE (1) | SE377938B (nl) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3932642A (en) * | 1971-04-10 | 1976-01-13 | Boehringer Ingelheim Gmbh | Biocidal compositions containing a 2- (5'-nitro-2'-furyl)-thieno(2,3-d) pyrimidine and methods of use |
US6187777B1 (en) | 1998-02-06 | 2001-02-13 | Amgen Inc. | Compounds and methods which modulate feeding behavior and related diseases |
US6608053B2 (en) * | 2000-04-27 | 2003-08-19 | Yamanouchi Pharmaceutical Co., Ltd. | Fused heteroaryl derivatives |
US20040138238A1 (en) * | 2002-08-08 | 2004-07-15 | Dhanoa Dale S. | Substituted aminopyrimidine compounds as neurokinin antagonists |
GB0423653D0 (en) * | 2004-10-25 | 2004-11-24 | Piramed Ltd | Pharmaceutical compounds |
CL2007001166A1 (es) | 2006-04-26 | 2008-01-25 | Piramed Ltd | Compuestos derivados de pirimidina condensada, inhibidores de pi3-quinasa; procesos para preparar los compuestos; composicion farmaceutica que los comprende; uso de los compuestos en la preparacion de medicamentos; proceso para preparar la composicion farmaceutica; y kit que incluye a la composicion farmaceutica |
NZ572812A (en) * | 2006-04-26 | 2010-09-30 | Hoffmann La Roche | THIENO [3, 2-D] PYRIMIDINE Indazole DERIVATIVE USEFUL AS PI3K INHIBITOR |
ATE532788T1 (de) * | 2006-04-26 | 2011-11-15 | Hoffmann La Roche | Pharmazeutische verbindungen |
EP2114950B1 (en) * | 2006-12-07 | 2016-03-09 | Genentech, Inc. | Phosphoinositide 3-kinase inhibitor compounds and methods of use |
ES2544082T3 (es) * | 2006-12-07 | 2015-08-27 | F. Hoffmann-La Roche Ag | Compuestos inhibidores de fosfoinosítido 3-quinasa y métodos de uso |
CN101679456B (zh) * | 2007-06-12 | 2012-09-05 | 霍夫曼-拉罗奇有限公司 | 噻唑并嘧啶类和它们作为磷脂酰肌醇3-激酶的抑制剂的应用 |
EP2207781B1 (en) * | 2007-09-24 | 2012-11-28 | Genentech, Inc. | Thiazolopyrimidine p13k inhibitor compounds and methods of use |
EP2214675B1 (en) | 2007-10-25 | 2013-11-20 | Genentech, Inc. | Process for making thienopyrimidine compounds |
GB0721095D0 (en) * | 2007-10-26 | 2007-12-05 | Piramed Ltd | Pharmaceutical compounds |
CN102369011A (zh) | 2009-03-12 | 2012-03-07 | 健泰科生物技术公司 | 用于治疗造血恶性肿瘤的磷酸肌醇3-激酶抑制剂化合物与化学治疗剂的组合 |
US8158625B2 (en) * | 2009-05-27 | 2012-04-17 | Genentech, Inc. | Bicyclic indole-pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of use |
JP5781066B2 (ja) | 2009-05-27 | 2015-09-16 | ジェネンテック, インコーポレイテッド | p110δに対して選択的な二環式ピリミジンPI3K阻害剤化合物及び使用方法 |
MX345155B (es) * | 2009-10-12 | 2017-01-18 | F Hoffmann-La Roche Ag * | Combinaciones de un inhibidor de pi3k y un inhibidor de mek. |
EP2558864A1 (en) | 2010-04-16 | 2013-02-20 | Genentech, Inc. | Fox03a as predictive biomarker for pi3k/akt kinase pathway inhibitor efficacy |
US20140004209A1 (en) | 2010-12-22 | 2014-01-02 | Genentech, Inc. | Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms |
CN105247072B (zh) | 2013-02-25 | 2019-10-15 | 基因泰克公司 | 检测和治疗抗药性akt突变体的方法和组合物 |
-
0
- BE BE759493D patent/BE759493A/xx unknown
-
1970
- 1970-11-17 BG BG016080A patent/BG17799A3/xx unknown
- 1970-11-17 BG BG017732A patent/BG17800A3/xx unknown
- 1970-11-18 US US90841A patent/US3661908A/en not_active Expired - Lifetime
- 1970-11-23 CH CH1514674A patent/CH567029A5/xx not_active IP Right Cessation
- 1970-11-23 CH CH1731270A patent/CH559210A5/xx not_active IP Right Cessation
- 1970-11-23 CH CH1514974A patent/CH568324A5/xx not_active IP Right Cessation
- 1970-11-25 NL NL7017210A patent/NL7017210A/xx unknown
- 1970-11-25 GB GB5614670A patent/GB1321316A/en not_active Expired
- 1970-11-25 DK DK601570AA patent/DK128781B/da unknown
- 1970-11-25 NO NO04524/70A patent/NO129954B/no unknown
- 1970-11-26 CA CA099166A patent/CA926865A/en not_active Expired
- 1970-11-26 FR FR7042531A patent/FR2073416B1/fr not_active Expired
- 1970-11-26 IL IL35729A patent/IL35729A/xx unknown
- 1970-11-26 SE SE7016054A patent/SE377938B/xx unknown
- 1970-11-26 IE IE1519/70A patent/IE34765B1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
US3661908A (en) | 1972-05-09 |
BE759493A (fr) | 1971-05-25 |
BG17800A3 (bg) | 1973-12-25 |
SE377938B (nl) | 1975-08-04 |
CH568324A5 (nl) | 1975-10-31 |
IL35729A0 (en) | 1971-01-28 |
FR2073416B1 (nl) | 1975-04-18 |
CH567029A5 (nl) | 1975-09-30 |
NL7017210A (nl) | 1971-05-28 |
IE34765B1 (en) | 1975-08-06 |
GB1321316A (en) | 1973-06-27 |
FR2073416A1 (nl) | 1971-10-01 |
IE34765L (en) | 1971-05-26 |
CH559210A5 (nl) | 1975-02-28 |
DK128781B (da) | 1974-07-01 |
CA926865A (en) | 1973-05-22 |
BG17799A3 (bg) | 1973-12-25 |
NO129954B (nl) | 1974-06-17 |
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