IL35729A - 2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines,their preparation and pharmaceutical compositions containing them - Google Patents

2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL35729A
IL35729A IL35729A IL3572970A IL35729A IL 35729 A IL35729 A IL 35729A IL 35729 A IL35729 A IL 35729A IL 3572970 A IL3572970 A IL 3572970A IL 35729 A IL35729 A IL 35729A
Authority
IL
Israel
Prior art keywords
thieno
pyrimidines
furyl
nitro
preparation
Prior art date
Application number
IL35729A
Other languages
English (en)
Other versions
IL35729A0 (en
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19691959403 external-priority patent/DE1959403A1/de
Priority claimed from DE19702050815 external-priority patent/DE2050815A1/de
Priority claimed from DE19702050816 external-priority patent/DE2050816A1/de
Priority claimed from DE19702050814 external-priority patent/DE2050814A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of IL35729A0 publication Critical patent/IL35729A0/xx
Publication of IL35729A publication Critical patent/IL35729A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL35729A 1969-11-26 1970-11-26 2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines,their preparation and pharmaceutical compositions containing them IL35729A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19691959403 DE1959403A1 (de) 1969-11-26 1969-11-26 Neue 2-(5-Nitro-2-furyl)-thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
DE19702050815 DE2050815A1 (de) 1970-10-16 1970-10-16 Neue 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine
DE19702050816 DE2050816A1 (de) 1970-10-16 1970-10-16 Neue 2-(Nitro-2-furyl>thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine
DE19702050814 DE2050814A1 (de) 1970-10-16 1970-10-16 Neue Verfahren zur Herstellung von 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidinen

Publications (2)

Publication Number Publication Date
IL35729A0 IL35729A0 (en) 1971-01-28
IL35729A true IL35729A (en) 1974-01-14

Family

ID=27430978

Family Applications (1)

Application Number Title Priority Date Filing Date
IL35729A IL35729A (en) 1969-11-26 1970-11-26 2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines,their preparation and pharmaceutical compositions containing them

Country Status (13)

Country Link
US (1) US3661908A (cs)
BE (1) BE759493A (cs)
BG (2) BG17800A3 (cs)
CA (1) CA926865A (cs)
CH (3) CH568324A5 (cs)
DK (1) DK128781B (cs)
FR (1) FR2073416B1 (cs)
GB (1) GB1321316A (cs)
IE (1) IE34765B1 (cs)
IL (1) IL35729A (cs)
NL (1) NL7017210A (cs)
NO (1) NO129954B (cs)
SE (1) SE377938B (cs)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932642A (en) * 1971-04-10 1976-01-13 Boehringer Ingelheim Gmbh Biocidal compositions containing a 2- (5'-nitro-2'-furyl)-thieno(2,3-d) pyrimidine and methods of use
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
US20040138238A1 (en) * 2002-08-08 2004-07-15 Dhanoa Dale S. Substituted aminopyrimidine compounds as neurokinin antagonists
GB0423653D0 (en) 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
ATE532788T1 (de) * 2006-04-26 2011-11-15 Hoffmann La Roche Pharmazeutische verbindungen
TW200801012A (en) 2006-04-26 2008-01-01 Piramed Ltd Phosphoinositide 3-kinase inhibitor compounds and methods of use
ES2347187T3 (es) 2006-04-26 2010-10-26 F. Hoffmann-La Roche Ag Derivado de tieno(3,2-d)pirimidina, util como un inhibidor de pi3k.
AR064154A1 (es) * 2006-12-07 2009-03-18 Piramed Ltd Compuestos inhibidores de fodfoinostida 3- quinasas y composiciones farmaceuticas
ES2544082T3 (es) 2006-12-07 2015-08-27 F. Hoffmann-La Roche Ag Compuestos inhibidores de fosfoinosítido 3-quinasa y métodos de uso
CA2692050A1 (en) * 2007-06-12 2008-12-18 F.Hoffmann-La Roche Ag Thiazoliopyrimidines and their use as inhibitors of phosphatidylinositol-3 kinase
WO2009042607A1 (en) 2007-09-24 2009-04-02 Genentech, Inc. Thiazolopyrimidine p13k inhibitor compounds and methods of use
JP5348725B2 (ja) 2007-10-25 2013-11-20 ジェネンテック， インコーポレイテッド チエノピリミジン化合物の製造方法
GB0721095D0 (en) * 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
BRPI1006189A2 (pt) 2009-03-12 2020-08-18 Genentech Inc uso de uma combinação terapêutica, formulação farmacêutica, artigo de manufatura, produto, método para determinar compostos a serem utilizados em combinação para o tratamento de uma malignidade hematopoiética e método para selecionar compostos a serem utilizados em combinação para o tratamento de câncer
WO2010138589A1 (en) 2009-05-27 2010-12-02 Genentech, Inc. Bicyclic pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
SG182247A1 (en) * 2009-05-27 2012-08-30 Hoffmann La Roche Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
RU2563193C2 (ru) * 2009-10-12 2015-09-20 Ф.Хоффманн-Ля Рош Аг Комбинации ингибитора pi3k и ингибитора мек
CN103038643A (zh) 2010-04-16 2013-04-10 基因泰克公司 作为pi3k/akt激酶途径抑制剂效能的预测性生物标记的foxo3a
US20140004209A1 (en) 2010-12-22 2014-01-02 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
KR102182488B1 (ko) 2013-02-25 2020-11-24 제넨테크, 인크. 약물 내성 akt 돌연변이체의 검출 및 치료를 위한 방법 및 조성물

Also Published As

Publication number Publication date
CH568324A5 (cs) 1975-10-31
US3661908A (en) 1972-05-09
CH567029A5 (cs) 1975-09-30
BG17800A3 (bg) 1973-12-25
NL7017210A (cs) 1971-05-28
FR2073416A1 (cs) 1971-10-01
GB1321316A (en) 1973-06-27
BE759493A (fr) 1971-05-25
NO129954B (cs) 1974-06-17
FR2073416B1 (cs) 1975-04-18
BG17799A3 (bg) 1973-12-25
CH559210A5 (cs) 1975-02-28
IE34765L (en) 1971-05-26
IE34765B1 (en) 1975-08-06
DK128781B (da) 1974-07-01
SE377938B (cs) 1975-08-04
CA926865A (en) 1973-05-22
IL35729A0 (en) 1971-01-28

Similar Documents

Publication Publication Date Title
IL35729A (en) 2-(5-nitro-2-furyl)-thieno(3,2-d) pyrimidines,their preparation and pharmaceutical compositions containing them
IL36079A0 (en) 4-morpholino-thieno (3,2-d) pyrimidine derivatives,their production and pharmaceutical compositions containing them
IL39341A (en) Thieno(3,2-d)pyrimidines,their preparation and pharmaceutical compositions containing them
IL35078A (en) 2-aminoalkylamino-thieno (3,2-d) pyrimidines and their salts,their preparation and pharmaceutical compositions containing them
IL35688A (en) Substituted n-allyl-2-arylamino-imidazolines-(2),their preparation and pharmaceutical compositions containing them
IL33925A0 (en) Acetyl-guanidine derivatives,their preparation and pharmaceutical compositions containing them
IL35689A0 (en) 2-arylamino-imidazolines-(2),their preparation and pharmaceutical compositions containing them
IL39173A0 (en) 2-(5-nitro-2-furyl)-thieno(2,3-d)pyrimidines and salts thereof,their preparation and pharmaceutical compositions containing them
IL40800A0 (en) Thiazolo(5,4-d)pyrimidines,their preparation and pharmaceutical compositions containing them
ZA707999B (en) Improvements relating to 2-(5-nitro-2-furyl)-thieno(3,2-d)pyrimidines
IL35434A0 (en) Basically substituted tertiary butanols,their preparation and pharmaceutical compositions containing them
IL34947A0 (en) Pyridobenzodiazepin-6-one derivatives,their preparation and pharmaceutical compositions containing them
IL35779A (en) 4-amino-quinazoline derivatives,their preparation and pharmaceutical compositions containing them
IL35211A0 (en) 4-aryl-4-hydroxy-piperidine derivatives,their preparation and pharmaceutical compositions containing them
IL33821A (en) 1,3-dihydro-5-phenyl or pyridyl-2h-1,4-benzodiazepin-2-onederivatives,their preparation and pharmaceutical compositions containing them
IL34317A0 (en) Substituted acetamides,their preparation and pharmaceutical compositions containing them
IL33993A0 (en) Aminopropiophenones,their preparation and pharmaceutical compositions containing them
IL33947A0 (en) D-2-(6-substituted-2-naphthyl)propanals,their preparation and pharmaceutical compositions containing them
IL33979A (en) Amidine derivatives,their preparation and pharmaceutical compositions containing them
IL36096A0 (en) 2,6-dimorpholino-pyrimido (5,4-d) pyrimidine derivatives,their preparation and pharmaceutical compositions containing them
IL33321A (en) Pyrimidine derivatives,their preparation and pharmaceutical compositions containing them
IL33687A0 (en) Phenyl-thiazole derivatives,their preparation and pharmaceutical compositions containing them
HK67480A (en) 2-amino-4-(2-imidazolyl-vinyl)-pyrimidines, their preparation and use, and pharmaceutical compositions containing them
IL35086A (en) 1-(4-(thieno(2,3-b)(1,5)benzothiazepin-4-yl)-1-piperazinyl)-alkyl-imidazolidin-2-one derivatives,their preparation and pharmaceutical compositions containing them
IL32738A (en) 2,6-dimorpholino-8-hydroxyalkylamino-pyrimido(5,4-d)pyrimidines,their preparation and pharmaceutical compositions containing them