DK128781B - Analogifremgangsmåde til fremstilling af 2-(5-nitro-2-furyl)-thieno[3,2-d]-pyrimidiner. - Google Patents

Analogifremgangsmåde til fremstilling af 2-(5-nitro-2-furyl)-thieno[3,2-d]-pyrimidiner.

Info

Publication number
DK128781B
DK128781B DK601570AA DK601570A DK128781B DK 128781 B DK128781 B DK 128781B DK 601570A A DK601570A A DK 601570AA DK 601570 A DK601570 A DK 601570A DK 128781 B DK128781 B DK 128781B
Authority
DK
Denmark
Prior art keywords
thieno
pyrimidines
furyl
nitro
preparation
Prior art date
Application number
DK601570AA
Other languages
Danish (da)
English (en)
Inventor
E Woitun
W Reuter
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19691959403 external-priority patent/DE1959403A1/de
Priority claimed from DE19702050814 external-priority patent/DE2050814A1/de
Priority claimed from DE19702050815 external-priority patent/DE2050815A1/de
Priority claimed from DE19702050816 external-priority patent/DE2050816A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of DK128781B publication Critical patent/DK128781B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK601570AA 1969-11-26 1970-11-25 Analogifremgangsmåde til fremstilling af 2-(5-nitro-2-furyl)-thieno[3,2-d]-pyrimidiner. DK128781B (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19691959403 DE1959403A1 (de) 1969-11-26 1969-11-26 Neue 2-(5-Nitro-2-furyl)-thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
DE19702050814 DE2050814A1 (de) 1970-10-16 1970-10-16 Neue Verfahren zur Herstellung von 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidinen
DE19702050815 DE2050815A1 (de) 1970-10-16 1970-10-16 Neue 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine
DE19702050816 DE2050816A1 (de) 1970-10-16 1970-10-16 Neue 2-(Nitro-2-furyl>thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine

Publications (1)

Publication Number Publication Date
DK128781B true DK128781B (da) 1974-07-01

Family

ID=27430978

Family Applications (1)

Application Number Title Priority Date Filing Date
DK601570AA DK128781B (da) 1969-11-26 1970-11-25 Analogifremgangsmåde til fremstilling af 2-(5-nitro-2-furyl)-thieno[3,2-d]-pyrimidiner.

Country Status (13)

Country Link
US (1) US3661908A (cs)
BE (1) BE759493A (cs)
BG (2) BG17800A3 (cs)
CA (1) CA926865A (cs)
CH (3) CH567029A5 (cs)
DK (1) DK128781B (cs)
FR (1) FR2073416B1 (cs)
GB (1) GB1321316A (cs)
IE (1) IE34765B1 (cs)
IL (1) IL35729A (cs)
NL (1) NL7017210A (cs)
NO (1) NO129954B (cs)
SE (1) SE377938B (cs)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932642A (en) * 1971-04-10 1976-01-13 Boehringer Ingelheim Gmbh Biocidal compositions containing a 2- (5'-nitro-2'-furyl)-thieno(2,3-d) pyrimidine and methods of use
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
US20040138238A1 (en) * 2002-08-08 2004-07-15 Dhanoa Dale S. Substituted aminopyrimidine compounds as neurokinin antagonists
GB0423653D0 (en) * 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
KR101533461B1 (ko) 2006-04-26 2015-07-02 에프. 호프만-라 로슈 아게 Ｐｉ３ｋ저해제로 유용한 티에노［3,2-ｄ］피리미딘 유도체
AR060632A1 (es) 2006-04-26 2008-07-02 Genentech Inc Compuestos inhibidores de fosfoinositida 3- quinasa y metodos de uso
ATE532788T1 (de) * 2006-04-26 2011-11-15 Hoffmann La Roche Pharmazeutische verbindungen
PE20081679A1 (es) * 2006-12-07 2008-12-18 Hoffmann La Roche Compuestos del inhibidor de fosfoinositida 3-cinasa y metodos de uso
CN101675053B (zh) * 2006-12-07 2014-03-12 健泰科生物技术公司 磷酸肌醇3-激酶抑制剂化合物及使用方法
ATE510841T1 (de) * 2007-06-12 2011-06-15 Hoffmann La Roche Thiazoliopyrimidine und ihre verwendung als hemmer der phosphatidylinositol-3 kinase
CN101932587A (zh) * 2007-09-24 2010-12-29 吉宁特有限公司 噻唑并嘧啶pi3k抑制剂化合物及使用方法
ES2439705T3 (es) 2007-10-25 2014-01-24 Genentech, Inc. Proceso para la preparación de compuestos de tienopirimidina
GB0721095D0 (en) * 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
KR101781654B1 (ko) 2009-03-12 2017-09-25 제넨테크, 인크. 조혈 악성종양의 치료를 위한 포스포이노시티드 ３-키나제 억제제 화합물 및 화학요법제의 조합물
US8158625B2 (en) * 2009-05-27 2012-04-17 Genentech, Inc. Bicyclic indole-pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of use
BRPI1009022A2 (pt) 2009-05-27 2016-03-08 Hoffmann La Roche "composto, composição farmacêutica, processo para produzir uma composição farmacêutica, uso de um composto, método para tratamento de uma doença ou transtorno e kit"
MA33974B1 (fr) * 2009-10-12 2013-02-01 Hoffmann La Roche Combinaisons d'un inhibiteur de pi3k et d'un inhibiteur de mek
CA2793892A1 (en) 2010-04-16 2011-10-20 Elizabeth Punnoose Foxo3a as predictive biomarker for pi3k/akt kinase pathway inhibitor efficacy
WO2012088254A1 (en) 2010-12-22 2012-06-28 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
KR102182488B1 (ko) 2013-02-25 2020-11-24 제넨테크, 인크. 약물 내성 akt 돌연변이체의 검출 및 치료를 위한 방법 및 조성물

Also Published As

Publication number Publication date
IE34765L (en) 1971-05-26
GB1321316A (en) 1973-06-27
SE377938B (cs) 1975-08-04
NO129954B (cs) 1974-06-17
CH559210A5 (cs) 1975-02-28
CA926865A (en) 1973-05-22
FR2073416B1 (cs) 1975-04-18
IL35729A0 (en) 1971-01-28
BG17800A3 (bg) 1973-12-25
BE759493A (fr) 1971-05-25
NL7017210A (cs) 1971-05-28
CH568324A5 (cs) 1975-10-31
CH567029A5 (cs) 1975-09-30
BG17799A3 (bg) 1973-12-25
US3661908A (en) 1972-05-09
IL35729A (en) 1974-01-14
IE34765B1 (en) 1975-08-06
FR2073416A1 (cs) 1971-10-01

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