IL32278A - 3-aryloxyalkyl or aralkyl piperidines,their preparation and pharmaceutical compositions containing them - Google Patents
3-aryloxyalkyl or aralkyl piperidines,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL32278A IL32278A IL32278A IL3227869A IL32278A IL 32278 A IL32278 A IL 32278A IL 32278 A IL32278 A IL 32278A IL 3227869 A IL3227869 A IL 3227869A IL 32278 A IL32278 A IL 32278A
- Authority
- IL
- Israel
- Prior art keywords
- piperidine
- acid
- addition salts
- mixture
- carbon atoms
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/02—Preparation by ring-closure or hydrogenation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/26—Radicals substituted by halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Farming Of Fish And Shellfish (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB27502/68A GB1203149A (en) | 1968-06-10 | 1968-06-10 | Piperidine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL32278A0 IL32278A0 (en) | 1969-07-30 |
| IL32278A true IL32278A (en) | 1972-10-29 |
Family
ID=10260615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL32278A IL32278A (en) | 1968-06-10 | 1969-05-22 | 3-aryloxyalkyl or aralkyl piperidines,their preparation and pharmaceutical compositions containing them |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US3634437A (ru) |
| JP (1) | JPS4934990B1 (ru) |
| AT (1) | AT289115B (ru) |
| BE (1) | BE734296A (ru) |
| BR (1) | BR6909577D0 (ru) |
| CH (1) | CH513856A (ru) |
| CS (1) | CS153519B2 (ru) |
| DE (1) | DE1929260A1 (ru) |
| DK (1) | DK120996B (ru) |
| ES (1) | ES368169A1 (ru) |
| FI (1) | FI49298C (ru) |
| FR (1) | FR2010615A1 (ru) |
| GB (1) | GB1203149A (ru) |
| IE (1) | IE33092B1 (ru) |
| IL (1) | IL32278A (ru) |
| NL (1) | NL6908842A (ru) |
| NO (1) | NO125928B (ru) |
| PL (1) | PL79996B1 (ru) |
| SE (1) | SE356978B (ru) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4556664A (en) * | 1984-03-13 | 1985-12-03 | Gunnar A. K. Aberg | Method and composition for the treatment of cardiac arrhythmias |
| IE66332B1 (en) * | 1986-11-03 | 1995-12-27 | Novo Nordisk As | Piperidine compounds and their preparation and use |
| US4822778A (en) * | 1988-01-19 | 1989-04-18 | Gunnar Aberg | Membrane stabilizing phenoxy-piperidine compounds and pharmaceutical compositions employing such compounds |
| FR2667317B1 (fr) * | 1990-10-02 | 1992-12-04 | Synthelabo | Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique. |
| GB9226111D0 (en) * | 1992-12-15 | 1993-02-10 | Smithkline Beecham Plc | Madicaments |
| US6110937A (en) * | 1997-04-03 | 2000-08-29 | Syntex Usa, Inc. | Phenoxymethyl piperidine derivatives for the treatment of neuropathic pain |
| CA2232147A1 (en) * | 1997-04-03 | 1998-10-03 | F. Hoffmann-La Roche Ag | Phenoxymethyl piperidine derivatives |
| ES2157148B1 (es) * | 1998-11-18 | 2002-03-01 | Faes Fabrica Espanola De Produ | Nuevas piperidinas 4-sustituidas. |
| US6518284B2 (en) * | 1998-11-18 | 2003-02-11 | Faes, Fabrica Espanola De Productos Quimicos Y Farmaceuticos S.A. | 4-substituted piperidines |
| EP1854785A1 (en) * | 2006-05-12 | 2007-11-14 | Faes Farma, S.A. | 4-[(3-fluorophenoxy)phenylmethyl]piperidine methanesulfonate: uses, process of synthesis and pharmaceutical compositions |
| US20100120858A1 (en) * | 2006-08-23 | 2010-05-13 | Pfizer Inc. | Piperidine Derivatives |
| JP5405571B2 (ja) * | 2008-07-24 | 2014-02-05 | セラヴァンス， インコーポレーテッド | ３−（フェノキシフェニルメチル）ピロリジン化合物 |
| JP2012524098A (ja) * | 2009-04-15 | 2012-10-11 | セラヴァンス， インコーポレーテッド | ３−（フェノキシピロリジン−３−イル−メチル）ヘテロアリール、３−（フェニルピロリジン−３−イルメトキシ）ヘテロアリールおよび３−（ヘテロアリールピロリジン−３−イルメトキシ）ヘテロアリール化合物 |
| JP5826173B2 (ja) | 2009-07-13 | 2015-12-02 | セラヴァンス バイオファーマ アール＆ディー アイピー， エルエルシー | ３−フェノキシメチルピロリジン化合物 |
| JP5714580B2 (ja) | 2009-07-21 | 2015-05-07 | セラヴァンス バイオファーマ アール＆ディー アイピー， エルエルシー | ３−フェノキシメチルピロリジン化合物 |
| KR101114544B1 (ko) * | 2009-10-15 | 2012-03-07 | 한국원자력의학원 | Ｎｒｆ2 활성 억제제 및 그의 용도 |
| CN103153950B (zh) | 2010-10-11 | 2015-11-25 | 施万生物制药研发Ip有限责任公司 | 血清素再摄取抑制剂 |
| US8501964B2 (en) | 2010-12-03 | 2013-08-06 | Theravance, Inc. | Serotonin reuptake inhibitors |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3381013A (en) * | 1964-01-15 | 1968-04-30 | Bristol Myers Co | Heterocyclicamino ethers of benzylphenols |
-
1968
- 1968-06-10 GB GB27502/68A patent/GB1203149A/en not_active Expired
-
1969
- 1969-05-15 IE IE671/69A patent/IE33092B1/xx unknown
- 1969-05-19 PL PL1969133681A patent/PL79996B1/pl unknown
- 1969-05-19 US US825934A patent/US3634437A/en not_active Expired - Lifetime
- 1969-05-22 IL IL32278A patent/IL32278A/en unknown
- 1969-05-28 DK DK289269AA patent/DK120996B/da unknown
- 1969-06-02 FI FI691646A patent/FI49298C/fi active
- 1969-06-06 SE SE08089/69A patent/SE356978B/xx unknown
- 1969-06-09 BR BR209577/69A patent/BR6909577D0/pt unknown
- 1969-06-09 NO NO2370/69A patent/NO125928B/no unknown
- 1969-06-09 BE BE734296D patent/BE734296A/xx unknown
- 1969-06-09 ES ES368169A patent/ES368169A1/es not_active Expired
- 1969-06-09 CS CS406769A patent/CS153519B2/cs unknown
- 1969-06-10 FR FR6919217A patent/FR2010615A1/fr not_active Withdrawn
- 1969-06-10 JP JP44045698A patent/JPS4934990B1/ja active Pending
- 1969-06-10 AT AT549669A patent/AT289115B/de not_active IP Right Cessation
- 1969-06-10 CH CH878169A patent/CH513856A/de not_active IP Right Cessation
- 1969-06-10 DE DE19691929260 patent/DE1929260A1/de active Pending
- 1969-06-10 NL NL6908842A patent/NL6908842A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL79996B1 (ru) | 1975-08-30 |
| DK120996B (da) | 1971-08-16 |
| NO125928B (ru) | 1972-11-27 |
| FI49298C (fi) | 1975-05-12 |
| DE1929260A1 (de) | 1970-08-27 |
| CH513856A (de) | 1971-10-15 |
| JPS4934990B1 (ru) | 1974-09-19 |
| NL6908842A (ru) | 1969-12-12 |
| SE356978B (ru) | 1973-06-12 |
| IE33092L (en) | 1969-12-10 |
| BE734296A (ru) | 1969-12-09 |
| GB1203149A (en) | 1970-08-26 |
| CS153519B2 (ru) | 1974-02-25 |
| BR6909577D0 (pt) | 1973-05-24 |
| FR2010615A1 (ru) | 1970-02-20 |
| IL32278A0 (en) | 1969-07-30 |
| FI49298B (ru) | 1975-01-31 |
| AT289115B (de) | 1971-04-13 |
| IE33092B1 (en) | 1974-03-20 |
| ES368169A1 (es) | 1971-05-01 |
| US3634437A (en) | 1972-01-11 |
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