IL301455B2 - Storage systems containing glatiramer acetate - Google Patents

Storage systems containing glatiramer acetate

Info

Publication number
IL301455B2
IL301455B2 IL301455A IL30145523A IL301455B2 IL 301455 B2 IL301455 B2 IL 301455B2 IL 301455 A IL301455 A IL 301455A IL 30145523 A IL30145523 A IL 30145523A IL 301455 B2 IL301455 B2 IL 301455B2
Authority
IL
Israel
Prior art keywords
depot formulation
depot
patient
certain embodiments
glatiramer
Prior art date
Application number
IL301455A
Other languages
English (en)
Hebrew (he)
Other versions
IL301455B1 (en
IL301455A (en
Inventor
Rubnov Shai
Bleich Kimelman Nadav
Marom Ehud
Danon Uri
Original Assignee
Mapi Pharma Ltd
Rubnov Shai
Bleich Kimelman Nadav
Marom Ehud
Danon Uri
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mapi Pharma Ltd, Rubnov Shai, Bleich Kimelman Nadav, Marom Ehud, Danon Uri filed Critical Mapi Pharma Ltd
Publication of IL301455A publication Critical patent/IL301455A/en
Publication of IL301455B1 publication Critical patent/IL301455B1/en
Publication of IL301455B2 publication Critical patent/IL301455B2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/02Peptides of undefined number of amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/593Polyesters, e.g. PLGA or polylactide-co-glycolide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Epoxy Resins (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Chemical Vapour Deposition (AREA)
IL301455A 2016-08-31 2017-08-09 Storage systems containing glatiramer acetate IL301455B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662381598P 2016-08-31 2016-08-31
PCT/IL2017/050882 WO2018042415A1 (en) 2016-08-31 2017-08-09 Depot systems comprising glatiramer acetate

Publications (3)

Publication Number Publication Date
IL301455A IL301455A (en) 2023-05-01
IL301455B1 IL301455B1 (en) 2023-12-01
IL301455B2 true IL301455B2 (en) 2024-04-01

Family

ID=61300274

Family Applications (2)

Application Number Title Priority Date Filing Date
IL301455A IL301455B2 (en) 2016-08-31 2017-08-09 Storage systems containing glatiramer acetate
IL264914A IL264914B2 (en) 2016-08-31 2019-02-19 Storage systems containing glatiramer acetate

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL264914A IL264914B2 (en) 2016-08-31 2019-02-19 Storage systems containing glatiramer acetate

Country Status (21)

Country Link
US (1) US12370233B2 (enExample)
EP (2) EP3506921B1 (enExample)
JP (1) JP7193448B2 (enExample)
CN (1) CN109982712A (enExample)
AU (1) AU2017319728B2 (enExample)
BR (1) BR112019003594A2 (enExample)
CA (1) CA3035147A1 (enExample)
DK (1) DK3506921T3 (enExample)
ES (2) ES3023741T3 (enExample)
FI (1) FI3506921T3 (enExample)
HR (2) HRP20250396T1 (enExample)
HU (2) HUE071047T2 (enExample)
IL (2) IL301455B2 (enExample)
LT (1) LT3506921T (enExample)
MX (1) MX2019002284A (enExample)
PL (2) PL4252849T3 (enExample)
PT (1) PT3506921T (enExample)
RS (2) RS66690B1 (enExample)
SI (1) SI3506921T1 (enExample)
SM (2) SMT202300251T1 (enExample)
WO (1) WO2018042415A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11471421B2 (en) 2016-08-28 2022-10-18 Mapi Pharma Ltd. Process for preparing microparticles containing glatiramer acetate
US12097292B2 (en) 2016-08-28 2024-09-24 Mapi Pharma Ltd. Process for preparing microparticles containing glatiramer acetate
US11167003B2 (en) 2017-03-26 2021-11-09 Mapi Pharma Ltd. Methods for suppressing or alleviating primary or secondary progressive multiple sclerosis (PPMS or SPMS) using sustained release glatiramer depot systems
US11865213B2 (en) * 2021-07-05 2024-01-09 Mapi Pharma Ltd. Semaglutide depot systems and use thereof
WO2023170493A1 (en) * 2022-03-07 2023-09-14 Hadidi Naghmeh Drug delivery using a parenteral pharmaceutical composition
EP4493274A1 (en) 2022-03-17 2025-01-22 Mapi Pharma Ltd. Depot systems comprising cariprazine or salts thereof

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