IL300023A - Low dose regimen and formulation of a 5-methyl-1,2,4-oxadiazol-3-yl compound - Google Patents

Low dose regimen and formulation of a 5-methyl-1,2,4-oxadiazol-3-yl compound

Info

Publication number
IL300023A
IL300023A IL300023A IL30002323A IL300023A IL 300023 A IL300023 A IL 300023A IL 300023 A IL300023 A IL 300023A IL 30002323 A IL30002323 A IL 30002323A IL 300023 A IL300023 A IL 300023A
Authority
IL
Israel
Prior art keywords
compound
pharmaceutically acceptable
total dose
day
acceptable salt
Prior art date
Application number
IL300023A
Other languages
English (en)
Hebrew (he)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL300023A publication Critical patent/IL300023A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IL300023A 2020-07-23 2021-07-23 Low dose regimen and formulation of a 5-methyl-1,2,4-oxadiazol-3-yl compound IL300023A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063055362P 2020-07-23 2020-07-23
PCT/US2021/042877 WO2022020663A1 (en) 2020-07-23 2021-07-23 Low dose regimen and formulation of a 5-methyl-1,2,4-oxadiazol-3-yl compound

Publications (1)

Publication Number Publication Date
IL300023A true IL300023A (en) 2023-03-01

Family

ID=77338898

Family Applications (1)

Application Number Title Priority Date Filing Date
IL300023A IL300023A (en) 2020-07-23 2021-07-23 Low dose regimen and formulation of a 5-methyl-1,2,4-oxadiazol-3-yl compound

Country Status (21)

Country Link
US (1) US20230338349A1 (https=)
EP (1) EP4185291B1 (https=)
JP (1) JP2023535034A (https=)
KR (1) KR20230043905A (https=)
CN (1) CN116323604A (https=)
AR (1) AR123031A1 (https=)
AU (1) AU2021312894B2 (https=)
BR (1) BR112023000975A2 (https=)
CA (1) CA3186808A1 (https=)
CL (1) CL2023000194A1 (https=)
CO (1) CO2023000594A2 (https=)
DO (1) DOP2023000009A (https=)
EC (1) ECSP23005057A (https=)
ES (1) ES3039536T3 (https=)
IL (1) IL300023A (https=)
JO (1) JOP20230018A1 (https=)
MX (1) MX2023000993A (https=)
PE (1) PE20231031A1 (https=)
PH (1) PH12023550177A1 (https=)
TW (1) TW202220650A (https=)
WO (1) WO2022020663A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3243602A1 (en) 2022-02-03 2023-08-10 Eli Lilly And Company Regional Tau Imaging for the Diagnosis and Treatment of Alzheimer's Disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018014331A1 (zh) * 2016-07-22 2018-01-25 深圳市大富科技股份有限公司 Usb金属管件加工设备及其上模板
TWI654978B (zh) * 2017-01-27 2019-04-01 美商美國禮來大藥廠 5-甲基-1,2,4-二唑-3-基化合物
CA3107788A1 (en) * 2018-07-31 2020-02-06 Eli Lilly And Company Combination of anti-tau antibody and oga inhibitor for treatment of diseases characterized by aberrant tau aggregation

Also Published As

Publication number Publication date
EP4185291B1 (en) 2025-07-09
AU2021312894B2 (en) 2025-09-11
WO2022020663A1 (en) 2022-01-27
MX2023000993A (es) 2023-03-01
CO2023000594A2 (es) 2023-01-26
PE20231031A1 (es) 2023-07-10
CL2023000194A1 (es) 2023-07-21
CN116323604A (zh) 2023-06-23
ECSP23005057A (es) 2023-02-28
JP2023535034A (ja) 2023-08-15
EP4185291A1 (en) 2023-05-31
CA3186808A1 (en) 2022-01-27
TW202220650A (zh) 2022-06-01
AR123031A1 (es) 2022-10-26
KR20230043905A (ko) 2023-03-31
EP4185291C0 (en) 2025-07-09
BR112023000975A2 (pt) 2023-02-07
DOP2023000009A (es) 2023-02-15
JOP20230018A1 (ar) 2023-01-23
PH12023550177A1 (en) 2024-03-18
US20230338349A1 (en) 2023-10-26
ES3039536T3 (en) 2025-10-22
AU2021312894A1 (en) 2023-02-23

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