PH12023550177A1 - Low dose regimen and formulation of a 5-methyl-1,2,4-oxadiazol-3-yl compound. - Google Patents

Low dose regimen and formulation of a 5-methyl-1,2,4-oxadiazol-3-yl compound.

Info

Publication number
PH12023550177A1
PH12023550177A1 PH1/2023/550177A PH12023550177A PH12023550177A1 PH 12023550177 A1 PH12023550177 A1 PH 12023550177A1 PH 12023550177 A PH12023550177 A PH 12023550177A PH 12023550177 A1 PH12023550177 A1 PH 12023550177A1
Authority
PH
Philippines
Prior art keywords
compound
oxadiazol
formulation
methyl
low dose
Prior art date
Application number
PH1/2023/550177A
Other languages
English (en)
Inventor
William Brian Kielbasa
Dustin James Mergott
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PH12023550177A1 publication Critical patent/PH12023550177A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
PH1/2023/550177A 2020-07-23 2021-07-23 Low dose regimen and formulation of a 5-methyl-1,2,4-oxadiazol-3-yl compound. PH12023550177A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US202063055362P 2020-07-23 2020-07-23

Publications (1)

Publication Number Publication Date
PH12023550177A1 true PH12023550177A1 (en) 2024-03-18

Family

ID=77338898

Family Applications (1)

Application Number Title Priority Date Filing Date
PH1/2023/550177A PH12023550177A1 (en) 2020-07-23 2021-07-23 Low dose regimen and formulation of a 5-methyl-1,2,4-oxadiazol-3-yl compound.

Country Status (21)

Country Link
US (1) US20230338349A1 (https=)
EP (1) EP4185291B1 (https=)
JP (1) JP2023535034A (https=)
KR (1) KR20230043905A (https=)
CN (1) CN116323604A (https=)
AR (1) AR123031A1 (https=)
AU (1) AU2021312894B2 (https=)
BR (1) BR112023000975A2 (https=)
CA (1) CA3186808A1 (https=)
CL (1) CL2023000194A1 (https=)
CO (1) CO2023000594A2 (https=)
DO (1) DOP2023000009A (https=)
EC (1) ECSP23005057A (https=)
ES (1) ES3039536T3 (https=)
IL (1) IL300023A (https=)
JO (1) JOP20230018A1 (https=)
MX (1) MX2023000993A (https=)
PE (1) PE20231031A1 (https=)
PH (1) PH12023550177A1 (https=)
TW (1) TW202220650A (https=)
WO (1) WO2022020663A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3243602A1 (en) 2022-02-03 2023-08-10 Eli Lilly And Company Regional Tau Imaging for the Diagnosis and Treatment of Alzheimer's Disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018014331A1 (zh) * 2016-07-22 2018-01-25 深圳市大富科技股份有限公司 Usb金属管件加工设备及其上模板
TWI654978B (zh) * 2017-01-27 2019-04-01 美商美國禮來大藥廠 5-甲基-1,2,4-二唑-3-基化合物
CA3107788A1 (en) * 2018-07-31 2020-02-06 Eli Lilly And Company Combination of anti-tau antibody and oga inhibitor for treatment of diseases characterized by aberrant tau aggregation

Also Published As

Publication number Publication date
EP4185291B1 (en) 2025-07-09
AU2021312894B2 (en) 2025-09-11
WO2022020663A1 (en) 2022-01-27
MX2023000993A (es) 2023-03-01
CO2023000594A2 (es) 2023-01-26
PE20231031A1 (es) 2023-07-10
CL2023000194A1 (es) 2023-07-21
CN116323604A (zh) 2023-06-23
ECSP23005057A (es) 2023-02-28
JP2023535034A (ja) 2023-08-15
EP4185291A1 (en) 2023-05-31
CA3186808A1 (en) 2022-01-27
IL300023A (en) 2023-03-01
TW202220650A (zh) 2022-06-01
AR123031A1 (es) 2022-10-26
KR20230043905A (ko) 2023-03-31
EP4185291C0 (en) 2025-07-09
BR112023000975A2 (pt) 2023-02-07
DOP2023000009A (es) 2023-02-15
JOP20230018A1 (ar) 2023-01-23
US20230338349A1 (en) 2023-10-26
ES3039536T3 (en) 2025-10-22
AU2021312894A1 (en) 2023-02-23

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