IL295169A - Engineered leucine decarboxylases - Google Patents

Engineered leucine decarboxylases

Info

Publication number
IL295169A
IL295169A IL295169A IL29516922A IL295169A IL 295169 A IL295169 A IL 295169A IL 295169 A IL295169 A IL 295169A IL 29516922 A IL29516922 A IL 29516922A IL 295169 A IL295169 A IL 295169A
Authority
IL
Israel
Prior art keywords
polypeptide
sequence
seq
engineered
amino acid
Prior art date
Application number
IL295169A
Other languages
English (en)
Hebrew (he)
Inventor
Joyce Liu
Leann Quertinmont Teadt
Nikki Dellas
Stephan Jenne
Faye Loan Du
Kristen Jean Vallieu
Kerryn Mccluskie
Original Assignee
Codexis Inc
Joyce Liu
Leann Quertinmont Teadt
Nikki Dellas
Stephan Jenne
Faye Loan Du
Kristen Jean Vallieu
Kerryn Mccluskie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Codexis Inc, Joyce Liu, Leann Quertinmont Teadt, Nikki Dellas, Stephan Jenne, Faye Loan Du, Kristen Jean Vallieu, Kerryn Mccluskie filed Critical Codexis Inc
Publication of IL295169A publication Critical patent/IL295169A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51—Lyases (4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/01—Carboxy-lyases (4.1.1)
    • C12Y401/01014—Valine decarboxylase (4.1.1.14)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL295169A 2020-02-04 2021-02-03 Engineered leucine decarboxylases IL295169A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202062970039P 2020-02-04 2020-02-04
PCT/US2021/016450 WO2021158686A1 (en) 2020-02-04 2021-02-03 Engineered leucine decarboxylases

Publications (1)

Publication Number Publication Date
IL295169A true IL295169A (en) 2022-09-01

Family

ID=77061734

Family Applications (1)

Application Number Title Priority Date Filing Date
IL295169A IL295169A (en) 2020-02-04 2021-02-03 Engineered leucine decarboxylases

Country Status (12)

Country Link
US (2) US12241100B2 (enExample)
EP (1) EP4103711A4 (enExample)
JP (2) JP2023512683A (enExample)
KR (1) KR20220137057A (enExample)
CN (1) CN116113691A (enExample)
AU (1) AU2021216389A1 (enExample)
BR (1) BR112022015139A2 (enExample)
CA (1) CA3168922A1 (enExample)
IL (1) IL295169A (enExample)
MX (1) MX2022009531A (enExample)
PH (1) PH12022551776A1 (enExample)
WO (1) WO2021158686A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4103711A4 (en) 2020-02-04 2024-02-28 Codexis, Inc. Engineered leucine decarboxylases
JP2024540358A (ja) * 2021-11-01 2024-10-31 シンティス バイオ，インコーポレイティド 工学操作ロイシン脱炭酸酵素
WO2023102499A1 (en) * 2021-12-02 2023-06-08 Codexis, Inc. Engineered threonine aldolases and amino acid decarboxylases

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Also Published As

Publication number Publication date
PH12022551776A1 (en) 2023-11-29
US20240018504A1 (en) 2024-01-18
EP4103711A1 (en) 2022-12-21
US12241100B2 (en) 2025-03-04
JP2025143444A (ja) 2025-10-01
MX2022009531A (es) 2022-09-09
JP2023512683A (ja) 2023-03-28
CN116113691A (zh) 2023-05-12
KR20220137057A (ko) 2022-10-11
WO2021158686A1 (en) 2021-08-12
US20210238575A1 (en) 2021-08-05
CA3168922A1 (en) 2021-08-12
BR112022015139A2 (pt) 2022-10-11
WO2021158686A8 (en) 2022-03-17
EP4103711A4 (en) 2024-02-28
AU2021216389A1 (en) 2022-08-11

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