IL293721A - Methods of treating cancer - Google Patents
Methods of treating cancerInfo
- Publication number
- IL293721A IL293721A IL293721A IL29372122A IL293721A IL 293721 A IL293721 A IL 293721A IL 293721 A IL293721 A IL 293721A IL 29372122 A IL29372122 A IL 29372122A IL 293721 A IL293721 A IL 293721A
- Authority
- IL
- Israel
- Prior art keywords
- cancer
- gpa
- pharmaceutically acceptable
- acceptable salt
- subject
- Prior art date
Links
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Landscapes
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| US201962946581P | 2019-12-11 | 2019-12-11 | |
| PCT/US2020/064317 WO2021119316A1 (en) | 2019-12-11 | 2020-12-10 | Methods of treating cancer |
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| JP (1) | JP2023505687A (https=) |
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| IL (1) | IL293721A (https=) |
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| JP2024528705A (ja) * | 2021-07-20 | 2024-07-30 | インスピルナ，インコーポレイテッド | がんのための治療としてのクレアチン輸送を阻害するための組成物及び方法 |
| KR102615692B1 (ko) * | 2021-10-13 | 2023-12-19 | 주식회사 휴엔켐 | 베타-구아니디노프로피온산을 포함하는 간섬유화 예방 또는 치료용 조성물 |
| KR102822799B1 (ko) * | 2022-11-09 | 2025-06-20 | 충남대학교산학협력단 | 베타-구아니디노프로피온산을 포함하는 장내 미생물 개선용 조성물 |
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| BR112014020103A2 (pt) | 2012-02-15 | 2018-10-09 | Aileron Therapeutics, Inc. | macrociclos peptidomiméticos |
| NZ703341A (en) | 2012-06-05 | 2016-11-25 | Neuroderm Ltd | Compositions comprising apomorphine and organic acids and uses thereof |
| CA2877030A1 (en) | 2012-06-22 | 2013-12-27 | Basf Se | Multicomponent crystals comprising imatinib mesilate and selected co-crystal formers |
| WO2014071067A2 (en) * | 2012-10-31 | 2014-05-08 | The Rockefeller University | Treatment and diagnosis of colon cancer |
| FR2997846B1 (fr) | 2012-11-09 | 2023-10-20 | Oreal | Composition comprenant un derive dicarbonyle et un acide, le procede de lissage des fibres keratiniques a partir de cette composition |
| WO2014138492A1 (en) | 2013-03-08 | 2014-09-12 | Solan, LLC | Methods for fabricating graphite-based structures and devices made therefrom |
| CN103288685B (zh) | 2013-07-03 | 2015-02-18 | 郭礼强 | 一种3-胍基丙酸的制备方法 |
| CN104341450B (zh) | 2013-08-09 | 2018-03-27 | 北京健峤医药科技有限公司 | 一种磷酸肌酸衍生物的合成与药学应用 |
| JP2018511645A (ja) * | 2015-04-17 | 2018-04-26 | ボストン バイオメディカル， インコーポレイテッド | 癌を治療するための方法 |
| WO2016176636A1 (en) | 2015-04-30 | 2016-11-03 | Rgenix, Inc. | Inhibitors of creatine transport and uses thereof |
| US20170056352A1 (en) * | 2015-08-25 | 2017-03-02 | Rgenix, Inc. | PHARMACEUTICALLY ACCEPTABLE SALTS OF beta-GUANIDINOPROPIONIC ACID WITH IMPROVED PROPERTIES AND USES THEREOF |
| WO2018160178A1 (en) * | 2017-03-01 | 2018-09-07 | Rgenix, Inc. | Pharmaceutically acceptable salts of b-guanidinopropionic acid with improved properties and uses thereof |
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2020
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- 2020-12-10 WO PCT/US2020/064317 patent/WO2021119316A1/en not_active Ceased
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- 2020-12-10 IL IL293721A patent/IL293721A/en unknown
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2024
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| TWI869511B (zh) | 2025-01-11 |
| EP4072561A4 (en) | 2023-11-29 |
| US12011427B2 (en) | 2024-06-18 |
| JP2023505687A (ja) | 2023-02-10 |
| TW202135792A (zh) | 2021-10-01 |
| WO2021119316A1 (en) | 2021-06-17 |
| AU2020402994A1 (en) | 2022-06-23 |
| EP4072561A1 (en) | 2022-10-19 |
| US20210177790A1 (en) | 2021-06-17 |
| US20240350442A1 (en) | 2024-10-24 |
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