IL293239A - Cell-permeable cyclic peptides and their uses - Google Patents
Cell-permeable cyclic peptides and their usesInfo
- Publication number
- IL293239A IL293239A IL293239A IL29323922A IL293239A IL 293239 A IL293239 A IL 293239A IL 293239 A IL293239 A IL 293239A IL 29323922 A IL29323922 A IL 29323922A IL 293239 A IL293239 A IL 293239A
- Authority
- IL
- Israel
- Prior art keywords
- independently selected
- 4alkyl
- optionally substituted
- cyclic peptide
- och3
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962938864P | 2019-11-21 | 2019-11-21 | |
| US202063047178P | 2020-07-01 | 2020-07-01 | |
| PCT/US2020/061596 WO2021102322A1 (en) | 2019-11-21 | 2020-11-20 | Cell-permeable cyclic peptides and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL293239A true IL293239A (en) | 2022-07-01 |
Family
ID=75981727
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL293239A IL293239A (en) | 2019-11-21 | 2020-11-20 | Cell-permeable cyclic peptides and their uses |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220411471A1 (https=) |
| EP (1) | EP4061397A4 (https=) |
| JP (1) | JP7836759B2 (https=) |
| CN (1) | CN115297883A (https=) |
| CA (1) | CA3159182A1 (https=) |
| IL (1) | IL293239A (https=) |
| WO (1) | WO2021102322A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202313092A (zh) * | 2021-05-26 | 2023-04-01 | 美商非自然產物公司 | 細胞可穿透環狀肽及其用途 |
| TW202417032A (zh) | 2022-08-23 | 2024-05-01 | 日商富士軟片股份有限公司 | 環肽或其鹽及ｍｄｍｘ抑制劑 |
| TW202417465A (zh) | 2022-08-23 | 2024-05-01 | 日商富士軟片股份有限公司 | 環肽或其鹽及ｍｄｍｘ抑制劑 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030166003A1 (en) * | 1999-06-14 | 2003-09-04 | Cochran Andrea G. | Structured peptide scaffold for displaying turn libraries on phage |
| AU2008360223B2 (en) * | 2008-08-08 | 2014-06-19 | Polyphor Ag | Template-fixed peptidomimetics |
| JP2014001189A (ja) * | 2012-06-20 | 2014-01-09 | Osaka Prefecture Univ | 抗腫瘍ペプチド化合物 |
| EP3243522A1 (en) * | 2016-05-10 | 2017-11-15 | Université Pierre et Marie Curie (Paris 6) | Agonist agents of cd47 inducing programmed cell death and their use in the treatments of diseases associated with defects in programmed cell death |
| CN110114075B (zh) * | 2016-11-09 | 2024-01-12 | 俄亥俄州国家创新基金会 | 含有二硫化物的细胞穿透肽及其制备和使用方法 |
| US11446388B2 (en) * | 2016-12-23 | 2022-09-20 | Heidelberg Pharma Research Gmbh | Amanitin antibody conjugates |
| CN110452289A (zh) * | 2019-07-10 | 2019-11-15 | 江苏申琅生物科技有限公司 | 一类新型mdm2环肽抑制剂的设计及其制备方法 |
-
2020
- 2020-11-20 CA CA3159182A patent/CA3159182A1/en active Pending
- 2020-11-20 WO PCT/US2020/061596 patent/WO2021102322A1/en not_active Ceased
- 2020-11-20 IL IL293239A patent/IL293239A/en unknown
- 2020-11-20 CN CN202080093855.7A patent/CN115297883A/zh active Pending
- 2020-11-20 EP EP20891387.1A patent/EP4061397A4/en active Pending
- 2020-11-20 JP JP2022529831A patent/JP7836759B2/ja active Active
-
2022
- 2022-05-20 US US17/750,110 patent/US20220411471A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA3159182A1 (en) | 2021-05-27 |
| CN115297883A (zh) | 2022-11-04 |
| US20220411471A1 (en) | 2022-12-29 |
| EP4061397A1 (en) | 2022-09-28 |
| WO2021102322A1 (en) | 2021-05-27 |
| EP4061397A4 (en) | 2023-11-29 |
| JP2023502745A (ja) | 2023-01-25 |
| JP7836759B2 (ja) | 2026-03-27 |
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