IL291697B2 - Diterpenoid compounds acting on protein kinase (pkc c) - Google Patents

Diterpenoid compounds acting on protein kinase (pkc c)

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Publication number
IL291697B2
IL291697B2 IL291697A IL29169722A IL291697B2 IL 291697 B2 IL291697 B2 IL 291697B2 IL 291697 A IL291697 A IL 291697A IL 29169722 A IL29169722 A IL 29169722A IL 291697 B2 IL291697 B2 IL 291697B2
Authority
IL
Israel
Prior art keywords
calkyl
ccycloalkyl
independently
optionally substituted
compound
Prior art date
Application number
IL291697A
Other languages
English (en)
Hebrew (he)
Other versions
IL291697B1 (en
IL291697A (en
Inventor
Chun Jiang
Ruihong Chen
Original Assignee
K Gen Inc
K Gen Therapeutics Inc
Chun Jiang
Ruihong Chen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by K Gen Inc, K Gen Therapeutics Inc, Chun Jiang, Ruihong Chen filed Critical K Gen Inc
Publication of IL291697A publication Critical patent/IL291697A/en
Publication of IL291697B1 publication Critical patent/IL291697B1/en
Publication of IL291697B2 publication Critical patent/IL291697B2/en

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P11/00—Drugs for disorders of the respiratory system
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
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    • C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C219/12—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the hydroxy groups esterified by a carboxylic acid having the esterifying carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
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