JP2022549353A5 - - Google Patents
Info
- Publication number
- JP2022549353A5 JP2022549353A5 JP2022519324A JP2022519324A JP2022549353A5 JP 2022549353 A5 JP2022549353 A5 JP 2022549353A5 JP 2022519324 A JP2022519324 A JP 2022519324A JP 2022519324 A JP2022519324 A JP 2022519324A JP 2022549353 A5 JP2022549353 A5 JP 2022549353A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- cycloalkyl
- optionally substituted
- independently
- heteroaryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025165441A JP2025186528A (ja) | 2019-09-24 | 2025-10-01 | プロテインキナーゼｃ（ｐｋｃ）に作用するジテルペノイド化合物 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962905253P | 2019-09-24 | 2019-09-24 | |
| US62/905,253 | 2019-09-24 | ||
| PCT/US2020/052545 WO2021062030A1 (en) | 2019-09-24 | 2020-09-24 | Diterpenoid compounds that act on protein kinase c (pkc) |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025165441A Division JP2025186528A (ja) | 2019-09-24 | 2025-10-01 | プロテインキナーゼｃ（ｐｋｃ）に作用するジテルペノイド化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022549353A JP2022549353A (ja) | 2022-11-24 |
| JP2022549353A5 true JP2022549353A5 (https=) | 2023-09-06 |
| JP7753201B2 JP7753201B2 (ja) | 2025-10-14 |
Family
ID=75165333
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022519324A Active JP7753201B2 (ja) | 2019-09-24 | 2020-09-24 | プロテインキナーゼｃ（ｐｋｃ）に作用するジテルペノイド化合物 |
| JP2025165441A Pending JP2025186528A (ja) | 2019-09-24 | 2025-10-01 | プロテインキナーゼｃ（ｐｋｃ）に作用するジテルペノイド化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025165441A Pending JP2025186528A (ja) | 2019-09-24 | 2025-10-01 | プロテインキナーゼｃ（ｐｋｃ）に作用するジテルペノイド化合物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20220411362A1 (https=) |
| EP (1) | EP4041268A4 (https=) |
| JP (2) | JP7753201B2 (https=) |
| KR (1) | KR20220116143A (https=) |
| CN (1) | CN114786697A (https=) |
| AU (1) | AU2020352641A1 (https=) |
| CA (1) | CA3155650A1 (https=) |
| IL (1) | IL291697B2 (https=) |
| WO (1) | WO2021062030A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20240197666A1 (en) * | 2021-03-23 | 2024-06-20 | K-Gen Therapeutics, Inc. | Diterpenoid compounds that act on protein kinase c (pkc) |
| JPWO2023033128A1 (https=) * | 2021-09-03 | 2023-03-09 | ||
| CN118973565A (zh) * | 2022-02-17 | 2024-11-15 | Q生物股份有限公司 | 组合疗法 |
| WO2025226622A1 (en) * | 2024-04-22 | 2025-10-30 | The Board Of Trustees Of The Leland Stanford Junior University | Tigilanol tiglate analogs, phorbol analogs, prodrugs, synthetic methods, and methods of use |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6063814A (en) * | 1997-04-14 | 2000-05-16 | Chang; Richard L. | Phorbol esters as anti-neoplastic and white blood cell elevating agents |
| US8816122B2 (en) * | 2009-07-20 | 2014-08-26 | The Board Of Trustees Of The Leland Stanford Junior University | Prostratin analogs, bryostatin analogs, prodrugs, synthetic methods, and methods of use |
| CA2855932A1 (en) * | 2011-11-13 | 2013-05-16 | Blanchette Rockefeller Neurosciences Institute | Pkc activators and combinations thereof |
| NZ727304A (en) * | 2012-01-18 | 2018-08-31 | Biosuccess Biotech Co Ltd | Compositions and methods of use of phorbol esters for the treatment of stroke |
| CN106659705A (zh) * | 2014-09-10 | 2017-05-10 | 加利福尼亚大学董事会 | 通过prostratin靶向k‑ras介导的信号转导通路和恶性肿瘤 |
| MA40904A (fr) * | 2014-11-03 | 2017-09-12 | Hygeia Tech Inc | Compositions d'ester de phorbol et procédés pour traiter ou réduire la durée d'une cytopénie |
| US20180311209A1 (en) * | 2015-10-08 | 2018-11-01 | Cognitive Research Enterprises, Inc. | Dosing regimens of pkc activators |
| WO2017156350A1 (en) * | 2016-03-09 | 2017-09-14 | K-Gen, Inc. | Methods of cancer treatment |
| US20240197666A1 (en) * | 2021-03-23 | 2024-06-20 | K-Gen Therapeutics, Inc. | Diterpenoid compounds that act on protein kinase c (pkc) |
-
2020
- 2020-09-24 IL IL291697A patent/IL291697B2/en unknown
- 2020-09-24 AU AU2020352641A patent/AU2020352641A1/en active Pending
- 2020-09-24 JP JP2022519324A patent/JP7753201B2/ja active Active
- 2020-09-24 US US17/763,611 patent/US20220411362A1/en active Pending
- 2020-09-24 WO PCT/US2020/052545 patent/WO2021062030A1/en not_active Ceased
- 2020-09-24 CN CN202080081644.1A patent/CN114786697A/zh active Pending
- 2020-09-24 KR KR1020227013445A patent/KR20220116143A/ko active Pending
- 2020-09-24 EP EP20867438.2A patent/EP4041268A4/en active Pending
- 2020-09-24 CA CA3155650A patent/CA3155650A1/en active Pending
-
2025
- 2025-10-01 JP JP2025165441A patent/JP2025186528A/ja active Pending
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