JP2018525399A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018525399A5 JP2018525399A5 JP2018507646A JP2018507646A JP2018525399A5 JP 2018525399 A5 JP2018525399 A5 JP 2018525399A5 JP 2018507646 A JP2018507646 A JP 2018507646A JP 2018507646 A JP2018507646 A JP 2018507646A JP 2018525399 A5 JP2018525399 A5 JP 2018525399A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- cancer
- alkenyl
- alkynyl
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562205411P | 2015-08-14 | 2015-08-14 | |
| US62/205,411 | 2015-08-14 | ||
| US201562261227P | 2015-11-30 | 2015-11-30 | |
| US62/261,227 | 2015-11-30 | ||
| US201662323287P | 2016-04-15 | 2016-04-15 | |
| US62/323,287 | 2016-04-15 | ||
| PCT/US2016/046292 WO2017030859A1 (en) | 2015-08-14 | 2016-08-10 | Cck2r-drug conjugates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018525399A JP2018525399A (ja) | 2018-09-06 |
| JP2018525399A5 true JP2018525399A5 (https=) | 2019-09-05 |
Family
ID=58051970
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018507646A Pending JP2018525399A (ja) | 2015-08-14 | 2016-08-10 | Ｃｃｋ２ｒ−薬物コンジュゲート |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10500286B2 (https=) |
| EP (1) | EP3334447A4 (https=) |
| JP (1) | JP2018525399A (https=) |
| CA (1) | CA2995371A1 (https=) |
| HK (1) | HK1257229A1 (https=) |
| WO (1) | WO2017030859A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11793880B2 (en) | 2015-12-04 | 2023-10-24 | Seagen Inc. | Conjugates of quaternized tubulysin compounds |
| CN108367043A (zh) | 2015-12-04 | 2018-08-03 | 西雅图基因公司 | 季铵化的微管溶素化合物的缀合物 |
| AU2022238571A1 (en) | 2021-03-18 | 2023-09-14 | Seagen Inc. | Selective drug release from internalized conjugates of biologically active compounds |
| CA3231129A1 (en) * | 2021-09-28 | 2023-04-06 | Anna POKORSKA-BOCCI | Method for predicting the response of a patient diagnosed with cancer to treatment and/or imaging with a compound targeting cck2-r, and compound for use in methods of selectively treating and/or imaging cancer |
| CN120554245B (zh) * | 2025-07-30 | 2026-02-27 | 辽宁众辉生物科技有限公司 | 一种氟吡菌酰胺中间体n-乙酰氧基甲基-2-三氟甲基苯甲酰胺的合成方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7776814B2 (en) * | 2002-07-09 | 2010-08-17 | R&D-Biopharmaceuticals Gmbh | Tubulysin conjugates |
| US8431714B2 (en) * | 2007-04-16 | 2013-04-30 | University Of Southern California | Synthesis of drug conjugates via reaction with epoxide-containing linkers |
| US10080805B2 (en) * | 2012-02-24 | 2018-09-25 | Purdue Research Foundation | Cholecystokinin B receptor targeting for imaging and therapy |
-
2016
- 2016-08-10 CA CA2995371A patent/CA2995371A1/en not_active Abandoned
- 2016-08-10 EP EP16837521.0A patent/EP3334447A4/en not_active Withdrawn
- 2016-08-10 HK HK18116265.4A patent/HK1257229A1/zh unknown
- 2016-08-10 JP JP2018507646A patent/JP2018525399A/ja active Pending
- 2016-08-10 WO PCT/US2016/046292 patent/WO2017030859A1/en not_active Ceased
- 2016-08-10 US US15/751,633 patent/US10500286B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018525399A5 (https=) | ||
| JPWO2020130125A5 (https=) | ||
| ES2815098T3 (es) | Conjugados de ligadores (ADCs) con inhibidores de KSP | |
| CN102946732B (zh) | 用作组蛋白脱乙酰酶抑制剂的大环化合物 | |
| CN106470696B (zh) | 用于治疗癌症的药物组合 | |
| ES2755101T3 (es) | Nuevos compuestos y conjugados de criptoficina, su preparación y su uso terapéutico | |
| RU2581834C1 (ru) | Новое пиперидиновое соединение или его соль | |
| US20190060473A1 (en) | Hsp90 inhibitor drug conjugates | |
| TW201620554A (zh) | 抗ｈｅｒ２抗體－藥物結合物 | |
| AU2012348017A1 (en) | Antibody-drug conjugates and related compounds, compositions, and methods | |
| MX2013013402A (es) | Inmunoconjugados, composiciones para prepararlos, y metodos prepararlos y uso. | |
| WO2014085575A1 (en) | Methods for treating cancer using combination therapies | |
| CA3083228A1 (en) | Small molecule degraders that recruit dcaft15 | |
| CA2968837A1 (en) | Methods of treating cancer by targeting tumor-associated macrophages | |
| JP2018509424A5 (https=) | ||
| AU2017214572A1 (en) | Glucose conjugates of triptolide, analogs and uses thereof | |
| JP2022541747A (ja) | 治療薬としての微小管標的化剤のペプチドコンジュゲート | |
| WO2023158679A2 (en) | Thiostrepton-inspired compounds for treatment of cancer and preparation thereof | |
| US20050287155A1 (en) | Conjugates with reduced adverse systemic effects | |
| JP6676650B2 (ja) | 疾患を処置するためのコンジュゲート | |
| WO2013149946A1 (en) | Functionalized thieno-indole derivatives for the treatment of cancer | |
| WO2016089879A1 (en) | Conjugates of garftase inhibitors | |
| JP2018525399A (ja) | Ｃｃｋ２ｒ−薬物コンジュゲート | |
| AU2017234676A1 (en) | Carbonic anhydrase IX targeting agents and methods | |
| TWI828068B (zh) | 作為組蛋白去乙醯酶抑制劑之巨環硫酯前藥 |