IL288417B2 - PPR protein causing less aggregation and use of the same - Google Patents

PPR protein causing less aggregation and use of the same

Info

Publication number
IL288417B2
IL288417B2 IL288417A IL28841721A IL288417B2 IL 288417 B2 IL288417 B2 IL 288417B2 IL 288417 A IL288417 A IL 288417A IL 28841721 A IL28841721 A IL 28841721A IL 288417 B2 IL288417 B2 IL 288417B2
Authority
IL
Israel
Prior art keywords
amino acid
formula
amino acids
sequence
ppr
Prior art date
Application number
IL288417A
Other languages
English (en)
Hebrew (he)
Other versions
IL288417B1 (en
IL288417A (en
Original Assignee
Editforce Inc
Univ Kyushu Nat Univ Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Editforce Inc, Univ Kyushu Nat Univ Corp filed Critical Editforce Inc
Publication of IL288417A publication Critical patent/IL288417A/en
Publication of IL288417B1 publication Critical patent/IL288417B1/en
Publication of IL288417B2 publication Critical patent/IL288417B2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/60Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Environmental Sciences (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL288417A 2019-05-29 2020-05-29 PPR protein causing less aggregation and use of the same IL288417B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2019100553 2019-05-29
PCT/JP2020/021473 WO2020241877A1 (ja) 2019-05-29 2020-05-29 凝集の少ないpprタンパク質及びその利用

Publications (3)

Publication Number Publication Date
IL288417A IL288417A (en) 2022-01-01
IL288417B1 IL288417B1 (en) 2024-06-01
IL288417B2 true IL288417B2 (en) 2024-10-01

Family

ID=73552159

Family Applications (2)

Application Number Title Priority Date Filing Date
IL288417A IL288417B2 (en) 2019-05-29 2020-05-29 PPR protein causing less aggregation and use of the same
IL312349A IL312349B2 (en) 2019-05-29 2020-05-29 The cause of least accumulation and use

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL312349A IL312349B2 (en) 2019-05-29 2020-05-29 The cause of least accumulation and use

Country Status (10)

Country Link
US (1) US12559528B2 (https=)
EP (1) EP3977849A4 (https=)
JP (4) JP7308468B2 (https=)
KR (1) KR102898966B1 (https=)
CN (1) CN113966340A (https=)
AU (2) AU2020283367B2 (https=)
CA (1) CA3142303A1 (https=)
IL (2) IL288417B2 (https=)
SG (1) SG11202113057XA (https=)
WO (1) WO2020241877A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7125727B1 (ja) 2021-09-07 2022-08-25 国立大学法人千葉大学 核酸配列改変用組成物および核酸配列の標的部位を改変する方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006188507A (ja) * 2004-12-10 2006-07-20 Tokyo Univ Of Agriculture & Technology 蛋白質の溶解度向上方法
WO2013058404A1 (ja) 2011-10-21 2013-04-25 国立大学法人九州大学 Pprモチーフを利用したrna結合性蛋白質の設計方法及びその利用
KR102893770B1 (ko) * 2013-04-22 2025-11-28 고쿠리쓰다이가쿠호진 규슈다이가쿠 피피알 단백질을 이용하는 dna 결합성 단백질 및 그의 이용
WO2017209122A1 (ja) 2016-06-03 2017-12-07 国立大学法人九州大学 標的mRNAからのタンパク質発現量を向上させるための融合タンパク質
JPWO2018030488A1 (ja) 2016-08-10 2019-06-13 富士フイルム和光純薬株式会社 Pprモチーフを利用したdna結合性タンパク質およびその利用
JP6918686B2 (ja) 2017-11-28 2021-08-11 東芝ライフスタイル株式会社 冷蔵庫
KR102568600B1 (ko) 2018-02-19 2023-08-23 삼성디스플레이 주식회사 표시 장치, 이를 포함하는 적층 기판, 및 표시 장치 제조방법
CN114729017A (zh) * 2019-05-29 2022-07-08 日商基因编辑力股份有限公司 Ppr蛋白的有效制作方法及其应用

Also Published As

Publication number Publication date
EP3977849A1 (en) 2022-04-06
JP7749763B2 (ja) 2025-10-06
CN113966340A (zh) 2022-01-21
IL312349B1 (en) 2024-12-01
CA3142303A1 (en) 2020-12-03
JP2024138381A (ja) 2024-10-08
IL312349B2 (en) 2025-04-01
IL288417B1 (en) 2024-06-01
AU2020283367B2 (en) 2025-04-10
SG11202113057XA (en) 2021-12-30
US20220220166A1 (en) 2022-07-14
JPWO2020241877A1 (https=) 2020-12-03
BR112021023937A2 (pt) 2022-04-19
WO2020241877A1 (ja) 2020-12-03
IL312349A (en) 2024-06-01
JP7526399B2 (ja) 2024-08-01
AU2025205185A1 (en) 2025-07-31
EP3977849A4 (en) 2023-06-28
JP7308468B2 (ja) 2023-07-14
KR20220023984A (ko) 2022-03-03
IL288417A (en) 2022-01-01
AU2020283367A1 (en) 2022-01-06
US12559528B2 (en) 2026-02-24
NZ783357A (en) 2025-06-27
JP2023036848A (ja) 2023-03-14
KR102898966B1 (ko) 2025-12-10
JP2025181985A (ja) 2025-12-11

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