IL283930A - התקן להפרדת תאים ושיטות שימוש - Google Patents

התקן להפרדת תאים ושיטות שימוש

Info

Publication number
IL283930A
IL283930A IL283930A IL28393021A IL283930A IL 283930 A IL283930 A IL 283930A IL 283930 A IL283930 A IL 283930A IL 28393021 A IL28393021 A IL 28393021A IL 283930 A IL283930 A IL 283930A
Authority
IL
Israel
Prior art keywords
methods
separation apparatus
cell separation
cell
separation
Prior art date
Application number
IL283930A
Other languages
English (en)
Inventor
Rolf Wolters
Jules Valenti
Tom Gurski
Original Assignee
Orgenesis Inc
Koligo Therapeutics Inc
Rolf Wolters
Jules Valenti
Tom Gurski
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orgenesis Inc, Koligo Therapeutics Inc, Rolf Wolters, Jules Valenti, Tom Gurski filed Critical Orgenesis Inc
Publication of IL283930A publication Critical patent/IL283930A/he

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00—Means for pre-treatment of biological substances
    • C12M45/09—Means for pre-treatment of biological substances by enzymatic treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/28—Constructional details, e.g. recesses, hinges disposable or single use
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/14—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus with filters, sieves or membranes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C12M37/02—Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00—Means for pre-treatment of biological substances
    • C12M45/02—Means for pre-treatment of biological substances by mechanical forces; Stirring; Trituration; Comminuting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00—Means for pre-treatment of biological substances
    • C12M45/05—Means for pre-treatment of biological substances by centrifugation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Analytical Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Botany (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Thermal Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Clinical Laboratory Science (AREA)
  • Mechanical Engineering (AREA)
  • Computer Hardware Design (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Centrifugal Separators (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL283930A 2018-12-13 2021-06-13 התקן להפרדת תאים ושיטות שימוש IL283930A (he)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2018/065405 WO2020122916A1 (en) 2018-12-13 2018-12-13 Cell separation apparatus and methods of use

Publications (1)

Publication Number Publication Date
IL283930A true IL283930A (he) 2021-07-29

Family

ID=71076920

Family Applications (1)

Application Number Title Priority Date Filing Date
IL283930A IL283930A (he) 2018-12-13 2021-06-13 התקן להפרדת תאים ושיטות שימוש

Country Status (11)

Country Link
EP (1) EP3893949A4 (he)
JP (1) JP2022522323A (he)
KR (1) KR20210092324A (he)
CN (1) CN113660961A (he)
AU (1) AU2018452704A1 (he)
BR (1) BR112021011482A2 (he)
CA (1) CA3123386A1 (he)
IL (1) IL283930A (he)
MX (1) MX2021007080A (he)
WO (1) WO2020122916A1 (he)
ZA (1) ZA202104197B (he)

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5035708A (en) * 1985-06-06 1991-07-30 Thomas Jefferson University Endothelial cell procurement and deposition kit
FR2729398A1 (fr) * 1995-01-17 1996-07-19 Hospal R & D Int Dispositif de digestion d'organe et procede pour isoler des cellules ou amas de cellules d'interet biologique a partir d'un organe
US6235534B1 (en) * 1998-04-27 2001-05-22 Ronald Frederich Brookes Incremental absorbance scanning of liquid in dispensing tips
JP2002068995A (ja) * 2000-08-25 2002-03-08 Phoenix Seiyaku Kk 糖尿病治療剤
US7045349B2 (en) * 2001-01-23 2006-05-16 Benedict Daniel J Method of islet isolation using process control
US7585670B2 (en) * 2001-12-07 2009-09-08 Cytori Therapeutics, Inc. Automated methods for isolating and using clinically safe adipose derived regenerative cells
US9144583B2 (en) * 2002-03-29 2015-09-29 Tissue Genesis, Inc. Cell separation apparatus and methods of use
JP2004033006A (ja) * 2002-06-28 2004-02-05 Asahi Kasei Corp 生物由来材料の消化・細胞回収方法およびその装置
CN1842589B (zh) * 2003-06-25 2012-04-25 马克罗珀尔生物外科公司 用于从组织分离并且浓缩再生细胞的系统和方法
US7541166B2 (en) * 2003-09-19 2009-06-02 Microfluidic Systems, Inc. Sonication to selectively lyse different cell types
WO2010064973A1 (en) * 2008-12-01 2010-06-10 General Electric Company System and method for separating cells from body fluids
JP2011097878A (ja) * 2009-11-06 2011-05-19 Olympus Corp 細胞分離装置
US20110111497A1 (en) * 2009-11-06 2011-05-12 Olympus Corporation Cell separation apparatus, method for activating fat-derived cells, graft material producing process, and graft material
US9206387B2 (en) * 2010-07-09 2015-12-08 The Gid Group, Inc. Method and apparatus for processing adipose tissue
KR101951055B1 (ko) * 2010-12-16 2019-02-21 인제네론 인코포레이티드 조직 검체로부터 세포 및 세포가 풍부한 기질의 강화된 회수를 위한 방법 및 기구
EP2834344B1 (en) * 2012-09-06 2016-07-20 The GID Group, Inc. Tissue processing apparatus and method for processing adipose tissue
AU2012396668B2 (en) * 2012-12-14 2016-07-28 Chong ZHENG Centrifugal dynamic filtering apparatus and cell separation system using same
CN103018224B (zh) * 2012-12-14 2015-07-29 中国科学院上海微系统与信息技术研究所 基于离心微流控技术的稀少细胞分离检测系统及方法
ES2787888T3 (es) * 2013-11-13 2020-10-19 Stempeutics Res Private Limited Un sistema y un método para el procesamiento de muestras de tejido biológico
KR101667848B1 (ko) * 2014-07-08 2016-10-19 (주)시지바이오 세포분리 용기 및 이를 이용한 세포분리 방법
JP6976864B2 (ja) * 2015-12-29 2021-12-08 サーモゲネシス コーポレーション 細胞分離装置、システム、及び方法

Also Published As

Publication number Publication date
AU2018452704A1 (en) 2021-07-29
CA3123386A1 (en) 2020-06-18
MX2021007080A (es) 2021-10-13
BR112021011482A2 (pt) 2021-08-31
WO2020122916A1 (en) 2020-06-18
CN113660961A (zh) 2021-11-16
EP3893949A4 (en) 2022-08-17
ZA202104197B (en) 2023-10-25
KR20210092324A (ko) 2021-07-23
EP3893949A1 (en) 2021-10-20
JP2022522323A (ja) 2022-04-18

Similar Documents

Publication Publication Date Title
IL292094A (he) ניואנטיגנים ושיטות לשימוש בהם
IL282757A (he) שיטות לבחירה ולגירוי תאים ומכשיר לכך
IL290417A (he) התקן מיקרופלואידי ושיטה לשימוש בו
IL266409A (he) מערכת התקן תרבית תאים ושיטות לשימוש בה
EP4081346A4 (en) MICROFLUIDIC DEVICE AND METHODS OF USE
HK1254815A1 (zh) 洗手間設備及其使用方法
GB2564774B (en) Seal apparatus and methods of use
GB201618414D0 (en) Regulated cell lines and methods of use thereof
GB201816911D0 (en) Apparatus and methods
SG11202011267XA (en) Apparatus and method of use thereof
GB201710376D0 (en) Seal apparatus and methods of use
SG10201702547QA (en) Methods of vibro-treating and vibro-treating apparatus
GB201704520D0 (en) Clamping apparatus and method of use thereof
GB201602521D0 (en) Filter apparatus and method of use thereof
GB201616637D0 (en) Multiplexer apparatus and method of use thereof
IL283930A (he) התקן להפרדת תאים ושיטות שימוש
GB2588346B (en) Apparatus and methods
IL268171A (he) שיטה והתקן לבדיקת תאים
GB202001263D0 (en) Construction apparatus and method of use thereof
GB201814600D0 (en) Support apparatus and method of use thereof
GB201800151D0 (en) Clamp apparatus and method of use thereof
GB201711933D0 (en) Closure apparatus and method of use thereof
GB201608991D0 (en) Mult-band filter apparatus and method of use thereof
GB201602076D0 (en) Sampling apparatus and method of use thereof
GB201408743D0 (en) Battery charging apparatus and method of use thereof