EP3893949A4 - Cell separation apparatus and methods of use - Google Patents
Cell separation apparatus and methods of use Download PDFInfo
- Publication number
- EP3893949A4 EP3893949A4 EP18943193.5A EP18943193A EP3893949A4 EP 3893949 A4 EP3893949 A4 EP 3893949A4 EP 18943193 A EP18943193 A EP 18943193A EP 3893949 A4 EP3893949 A4 EP 3893949A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- methods
- separation apparatus
- cell separation
- cell
- separation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M45/00—Means for pre-treatment of biological substances
- C12M45/09—Means for pre-treatment of biological substances by enzymatic treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/28—Constructional details, e.g. recesses, hinges disposable or single use
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C12M33/14—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus with filters, sieves or membranes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
- C12M37/02—Filters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/48—Automatic or computerized control
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M45/00—Means for pre-treatment of biological substances
- C12M45/02—Means for pre-treatment of biological substances by mechanical forces; Stirring; Trituration; Comminuting
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M45/00—Means for pre-treatment of biological substances
- C12M45/05—Means for pre-treatment of biological substances by centrifugation
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2018/065405 WO2020122916A1 (en) | 2018-12-13 | 2018-12-13 | Cell separation apparatus and methods of use |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3893949A1 EP3893949A1 (en) | 2021-10-20 |
EP3893949A4 true EP3893949A4 (en) | 2022-08-17 |
Family
ID=71076920
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP18943193.5A Pending EP3893949A4 (en) | 2018-12-13 | 2018-12-13 | Cell separation apparatus and methods of use |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP3893949A4 (en) |
JP (1) | JP2022522323A (en) |
KR (1) | KR20210092324A (en) |
CN (1) | CN113660961A (en) |
AU (1) | AU2018452704A1 (en) |
BR (1) | BR112021011482A2 (en) |
CA (1) | CA3123386A1 (en) |
IL (1) | IL283930A (en) |
MX (1) | MX2021007080A (en) |
WO (1) | WO2020122916A1 (en) |
ZA (1) | ZA202104197B (en) |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050260175A1 (en) * | 2001-12-07 | 2005-11-24 | Hedrick Marc H | Systems and methods for isolating and using clinically safe adipose derived regenerative cells |
US20110111497A1 (en) * | 2009-11-06 | 2011-05-12 | Olympus Corporation | Cell separation apparatus, method for activating fat-derived cells, graft material producing process, and graft material |
US9144583B2 (en) * | 2002-03-29 | 2015-09-29 | Tissue Genesis, Inc. | Cell separation apparatus and methods of use |
KR20160006076A (en) * | 2014-07-08 | 2016-01-18 | (주)시지바이오 | Container for separating stem cells from fattissue and method for separating stem cells from fattissue using the same |
US20160030486A1 (en) * | 2012-09-06 | 2016-02-04 | The Gid Group, Inc. | Preparation of compositions to treat and treatment of osteoarthritis using adipose-derived stromal vascular fraction cells |
US20160252537A1 (en) * | 2013-11-13 | 2016-09-01 | Stempeutics Research Private Limited | System and method for processing of biological tissue samples |
US20180207203A1 (en) * | 2010-07-09 | 2018-07-26 | The Gid Group, Inc. | Portable apparatus with mixing device and methods relating to collecting and processing human biological material comprising adipose |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5035708A (en) * | 1985-06-06 | 1991-07-30 | Thomas Jefferson University | Endothelial cell procurement and deposition kit |
US6235534B1 (en) * | 1998-04-27 | 2001-05-22 | Ronald Frederich Brookes | Incremental absorbance scanning of liquid in dispensing tips |
JP2002068995A (en) * | 2000-08-25 | 2002-03-08 | Phoenix Seiyaku Kk | Diabetes mellitus-treating agent |
MXPA06000062A (en) * | 2003-06-25 | 2006-04-07 | Macropore Biosurgery Inc | Systems and methods for separating and concentrating regenerative cells from tissue. |
US7541166B2 (en) * | 2003-09-19 | 2009-06-02 | Microfluidic Systems, Inc. | Sonication to selectively lyse different cell types |
JP5709758B2 (en) * | 2008-12-01 | 2015-04-30 | ゼネラル・エレクトリック・カンパニイ | System and method for separating cells from body fluids |
JP2011097878A (en) * | 2009-11-06 | 2011-05-19 | Olympus Corp | Cell separation apparatus |
JP6014045B2 (en) * | 2010-12-16 | 2016-10-25 | アルト,エックハルト,ユー. | Method and apparatus for concentrating and recovering cells and cell enrichment matrix from tissue samples |
CN103018224B (en) * | 2012-12-14 | 2015-07-29 | 中国科学院上海微系统与信息技术研究所 | Based on rare cells separation detecting system and the method for centrifugal microfluidic control techniques |
AU2012396668B2 (en) * | 2012-12-14 | 2016-07-28 | Chong ZHENG | Centrifugal dynamic filtering apparatus and cell separation system using same |
US9695394B1 (en) * | 2015-12-29 | 2017-07-04 | Syngen, Inc. | Cell separation devices, systems, and methods |
-
2018
- 2018-12-13 KR KR1020217022023A patent/KR20210092324A/en active Search and Examination
- 2018-12-13 WO PCT/US2018/065405 patent/WO2020122916A1/en unknown
- 2018-12-13 JP JP2021534340A patent/JP2022522323A/en active Pending
- 2018-12-13 MX MX2021007080A patent/MX2021007080A/en unknown
- 2018-12-13 AU AU2018452704A patent/AU2018452704A1/en active Pending
- 2018-12-13 BR BR112021011482-3A patent/BR112021011482A2/en not_active Application Discontinuation
- 2018-12-13 CN CN201880100677.9A patent/CN113660961A/en active Pending
- 2018-12-13 CA CA3123386A patent/CA3123386A1/en active Pending
- 2018-12-13 EP EP18943193.5A patent/EP3893949A4/en active Pending
-
2021
- 2021-06-13 IL IL283930A patent/IL283930A/en unknown
- 2021-06-18 ZA ZA2021/04197A patent/ZA202104197B/en unknown
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050260175A1 (en) * | 2001-12-07 | 2005-11-24 | Hedrick Marc H | Systems and methods for isolating and using clinically safe adipose derived regenerative cells |
US9144583B2 (en) * | 2002-03-29 | 2015-09-29 | Tissue Genesis, Inc. | Cell separation apparatus and methods of use |
US20110111497A1 (en) * | 2009-11-06 | 2011-05-12 | Olympus Corporation | Cell separation apparatus, method for activating fat-derived cells, graft material producing process, and graft material |
US20180207203A1 (en) * | 2010-07-09 | 2018-07-26 | The Gid Group, Inc. | Portable apparatus with mixing device and methods relating to collecting and processing human biological material comprising adipose |
US20160030486A1 (en) * | 2012-09-06 | 2016-02-04 | The Gid Group, Inc. | Preparation of compositions to treat and treatment of osteoarthritis using adipose-derived stromal vascular fraction cells |
US20160252537A1 (en) * | 2013-11-13 | 2016-09-01 | Stempeutics Research Private Limited | System and method for processing of biological tissue samples |
KR20160006076A (en) * | 2014-07-08 | 2016-01-18 | (주)시지바이오 | Container for separating stem cells from fattissue and method for separating stem cells from fattissue using the same |
Also Published As
Publication number | Publication date |
---|---|
AU2018452704A1 (en) | 2021-07-29 |
MX2021007080A (en) | 2021-10-13 |
EP3893949A1 (en) | 2021-10-20 |
CA3123386A1 (en) | 2020-06-18 |
JP2022522323A (en) | 2022-04-18 |
ZA202104197B (en) | 2023-10-25 |
BR112021011482A2 (en) | 2021-08-31 |
KR20210092324A (en) | 2021-07-23 |
WO2020122916A1 (en) | 2020-06-18 |
CN113660961A (en) | 2021-11-16 |
IL283930A (en) | 2021-07-29 |
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Legal Events
Date | Code | Title | Description |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
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17P | Request for examination filed |
Effective date: 20210630 |
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AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
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DAV | Request for validation of the european patent (deleted) | ||
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20220720 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12M 1/12 20060101ALI20220714BHEP Ipc: C12M 1/26 20060101ALI20220714BHEP Ipc: C12M 1/36 20060101ALI20220714BHEP Ipc: C12M 1/34 20060101ALI20220714BHEP Ipc: C12M 1/00 20060101ALI20220714BHEP Ipc: C12M 1/33 20060101ALI20220714BHEP Ipc: A61L 27/36 20060101AFI20220714BHEP |
|
P01 | Opt-out of the competence of the unified patent court (upc) registered |
Effective date: 20230531 |