IL278976A - MUC16-specific chimeric antigen receptors and their use - Google Patents

MUC16-specific chimeric antigen receptors and their use

Info

Publication number
IL278976A
IL278976A IL278976A IL27897620A IL278976A IL 278976 A IL278976 A IL 278976A IL 278976 A IL278976 A IL 278976A IL 27897620 A IL27897620 A IL 27897620A IL 278976 A IL278976 A IL 278976A
Authority
IL
Israel
Prior art keywords
chimeric antigen
antigen receptors
specific chimeric
muc16
muc16 specific
Prior art date
Application number
IL278976A
Other languages
English (en)
Hebrew (he)
Inventor
Rutul R Shah
Helen Sabzevari
Original Assignee
Precigen Inc
Rutul R Shah
Helen Sabzevari
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Precigen Inc, Rutul R Shah, Helen Sabzevari filed Critical Precigen Inc
Publication of IL278976A publication Critical patent/IL278976A/en

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
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IL278976A 2018-06-04 2020-11-25 MUC16-specific chimeric antigen receptors and their use IL278976A (en)

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Application Number Priority Date Filing Date Title
US201862680297P 2018-06-04 2018-06-04
PCT/US2019/035384 WO2019236577A2 (en) 2018-06-04 2019-06-04 Muc16 specific chimeric antigen receptors and uses thereof

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IL278976A true IL278976A (en) 2021-01-31

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US (4) US11319380B2 (enExample)
EP (1) EP3802615A4 (enExample)
JP (2) JP2021525534A (enExample)
KR (1) KR20210021493A (enExample)
CN (1) CN112533957A (enExample)
AU (1) AU2019282620A1 (enExample)
CA (1) CA3101641A1 (enExample)
IL (1) IL278976A (enExample)
SG (1) SG11202011895VA (enExample)
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ZA (3) ZA202008065B (enExample)

Families Citing this family (10)

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Publication number Priority date Publication date Assignee Title
US11629340B2 (en) 2017-03-03 2023-04-18 Obsidian Therapeutics, Inc. DHFR tunable protein regulation
AU2018352984B2 (en) * 2017-10-18 2024-02-01 Precigen, Inc. Polypeptide compositions comprising spacers
AU2019372673A1 (en) * 2018-11-01 2021-05-27 Gracell Biotechnologies (Shanghai) Co., Ltd. Compositions and methods for T cell engineering
WO2021050789A1 (en) 2019-09-10 2021-03-18 Obsidian Therapeutics, Inc. Ca2-il15 fusion proteins for tunable regulation
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