IL275380A - Surfactant peptide nanostructures and uses in drug delivery - Google Patents
Surfactant peptide nanostructures and uses in drug deliveryInfo
- Publication number
- IL275380A IL275380A IL275380A IL27538020A IL275380A IL 275380 A IL275380 A IL 275380A IL 275380 A IL275380 A IL 275380A IL 27538020 A IL27538020 A IL 27538020A IL 275380 A IL275380 A IL 275380A
- Authority
- IL
- Israel
- Prior art keywords
- drug delivery
- peptide nanostructures
- surfactant peptide
- surfactant
- nanostructures
- Prior art date
Links
- 238000012377 drug delivery Methods 0.000 title 1
- 239000002086 nanomaterial Substances 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 239000004094 surface-active agent Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5192—Processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nanotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762599566P | 2017-12-15 | 2017-12-15 | |
| PCT/IB2018/001511 WO2019116092A1 (en) | 2017-12-15 | 2018-11-30 | Surfactant peptide nanostructures and uses in drug delivery |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL275380A true IL275380A (en) | 2020-07-30 |
Family
ID=65276214
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL275380A IL275380A (en) | 2017-12-15 | 2020-06-15 | Surfactant peptide nanostructures and uses in drug delivery |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11324703B2 (https=) |
| EP (1) | EP3723726A1 (https=) |
| JP (3) | JP2021506815A (https=) |
| CN (2) | CN117085140A (https=) |
| IL (1) | IL275380A (https=) |
| WO (1) | WO2019116092A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117085140A (zh) | 2017-12-15 | 2023-11-21 | 立美基股份有限公司 | 表面活性剂肽纳米结构及在药物递送中的用途 |
| EP3754336B1 (en) * | 2018-02-15 | 2024-01-17 | 3-D Matrix, Ltd. | Cancer lesion tissue evaluation for optimizing effect of boron neutron capture therapy |
| US20250059231A1 (en) * | 2021-09-30 | 2025-02-20 | Protinhi B.V. | Protease inhibitors |
Family Cites Families (81)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4582640A (en) | 1982-03-08 | 1986-04-15 | Collagen Corporation | Injectable cross-linked collagen implant material |
| US4466641A (en) | 1982-08-04 | 1984-08-21 | The Lockformer Company | Duct connecting system |
| US4642117A (en) | 1985-03-22 | 1987-02-10 | Collagen Corporation | Mechanically sheared collagen implant material and method |
| US4947840A (en) | 1987-08-21 | 1990-08-14 | Massachusetts Institute Of Technology | Biodegradable templates for the regeneration of tissues |
| US5236903A (en) | 1988-06-24 | 1993-08-17 | Ichiro Azuma | Polypeptide comprising repeated cell-adhesive core sequences |
| US5110604A (en) | 1988-06-30 | 1992-05-05 | Collagen Corporation | Processes for producing collagen matrixes and methods of using same |
| US5126141A (en) | 1988-11-16 | 1992-06-30 | Mediventures Incorporated | Composition and method for post-surgical adhesion reduction with thermo-irreversible gels of polyoxyalkylene polymers and ionic polysaccharides |
| US5550187A (en) | 1988-11-21 | 1996-08-27 | Collagen Corporation | Method of preparing crosslinked biomaterial compositions for use in tissue augmentation |
| US5629291A (en) | 1992-01-31 | 1997-05-13 | La Jolla Cancer Research Foundation | Methods of modulating fibronectin extracellular matrix assembly |
| US5292514A (en) | 1992-06-24 | 1994-03-08 | Minnesota Mining And Manufacturing Company | Azlactone-functional substrates, corneal prostheses, and manufacture and use thereof |
| US5955343A (en) | 1992-12-28 | 1999-09-21 | Massachusetts Institute Of Technology | Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor |
| US5670483A (en) | 1992-12-28 | 1997-09-23 | Massachusetts Insititute Of Technology | Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor |
| GB2274988A (en) | 1993-02-10 | 1994-08-17 | Mcconn Stern Rita | Iodine containing wound-healing preparations |
| US5709854A (en) | 1993-04-30 | 1998-01-20 | Massachusetts Institute Of Technology | Tissue formation by injecting a cell-polymeric solution that gels in vivo |
| US5773577A (en) | 1994-03-03 | 1998-06-30 | Protein Polymer Technologies | Products comprising substrates capable of enzymatic cross-linking |
| US5527610A (en) | 1994-05-20 | 1996-06-18 | The Uab Research Foundation | Elastomeric polypeptide matrices for preventing adhesion of biological materials |
| US5510102A (en) | 1995-01-23 | 1996-04-23 | The Regents Of The University Of California | Plasma and polymer containing surgical hemostatic adhesives |
| AU5638096A (en) | 1995-06-07 | 1996-12-30 | Clarion Pharmaceuticals, Inc. | Non-biological patch for hemostasis |
| US5736392A (en) | 1995-06-07 | 1998-04-07 | Life Technologies, Inc. | Peptide-enhanced cationic lipid transfections |
| RU2193897C2 (ru) | 1996-04-04 | 2002-12-10 | Бакстер Акциенгезельшафт | Гемостатическая губка, основанная на коллагене, способ ее получения, повязка для ран, включающая такую губку, и набор для приготовления повязки для ран |
| US6489446B1 (en) | 1996-08-07 | 2002-12-03 | Hsc Research And Development Limited Partnership | Self-aligning peptides modeled on human elastin and other fibrous proteins |
| AU6021598A (en) | 1997-01-09 | 1998-08-03 | Cohesion Technologies, Inc. | Methods and apparatuses for making swellable uniformly shaped devices from polymeric materials |
| US6224893B1 (en) | 1997-04-11 | 2001-05-01 | Massachusetts Institute Of Technology | Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering |
| US6428811B1 (en) | 1998-03-11 | 2002-08-06 | Wm. Marsh Rice University | Temperature-sensitive polymer/nanoshell composites for photothermally modulated drug delivery |
| US6046160A (en) | 1999-07-22 | 2000-04-04 | Deroyal Industries, Inc. | Composition and method for enhancing wound healing |
| WO2001087323A2 (en) | 2000-05-16 | 2001-11-22 | Genentech, Inc. | Method for treating cartilage disorders |
| US20020132274A1 (en) | 2001-01-17 | 2002-09-19 | Nevalainen Marja T. | Diagnostic and monitorings methods for cancer |
| PL206194B1 (pl) | 2001-01-25 | 2010-07-30 | Nycomed Pharma Asnycomed Pharma As | Sposób wytwarzania zawiesiny cząstek fibrynogenu i trombiny, zawiesina zawierająca fibrynogen, trombinę i alkohol oraz sposób powlekania nośnika taką zawiesiną |
| US7449180B2 (en) | 2001-02-06 | 2008-11-11 | John Kisiday | Macroscopic scaffold containing amphiphilic peptides encapsulating cells |
| EP1367961B1 (en) | 2001-02-06 | 2008-12-31 | Massachusetts Institute Of Technology | Peptide scaffold encapsulation of tissue cells and uses thereof |
| WO2003006043A1 (en) | 2001-07-10 | 2003-01-23 | Massachusetts Institute Of Technology | Surfactant peptide nanostructures, and uses thereof |
| WO2003084980A2 (en) | 2002-04-02 | 2003-10-16 | Northwestern University | Peptide amphiphile solutions and self assembled peptide nanofiber networks |
| WO2003095972A2 (en) | 2002-05-09 | 2003-11-20 | The Regents Of The University Of California | Method of analyzing ataxia-telangiectasia protein |
| WO2003096972A2 (en) | 2002-05-13 | 2003-11-27 | Massachusetts Institute Of Technology | Angiogenesis and cardiac tissue engineering with peptide hydrogels and related compositions and methods of use thereof |
| GB0216286D0 (en) | 2002-07-15 | 2002-08-21 | Univ Leeds | Network |
| AU2003261398A1 (en) | 2002-08-06 | 2004-02-23 | Epix Pharmaceuticals, Inc. | Peptide aggregates |
| US7713923B2 (en) | 2003-06-25 | 2010-05-11 | Massachusetts Institute Of Technology | Self-assembling peptides incorporating modifications and methods of use thereof |
| WO2005014615A2 (en) | 2003-06-25 | 2005-02-17 | Massachusetts Institute Of Technology | Self-assembling peptides incorporating modifications and methods of use thereof |
| GB0404374D0 (en) | 2004-02-27 | 2004-03-31 | Univ Manchester | Treatment of bacterial infections |
| EP3031466B1 (en) | 2004-07-06 | 2018-11-28 | 3D Matrix, Inc. | Purified amphiphilic peptide compositions and uses thereof |
| EP1833504A4 (en) | 2005-01-04 | 2009-08-12 | Brigham & Womens Hospital | PERMANENT DELIVERY OF SELF-ARRANGING PEPTIDE NANOFIBER USING THE PDGF |
| US9162005B2 (en) | 2005-04-25 | 2015-10-20 | Arch Biosurgery, Inc. | Compositions for prevention of adhesions and other barrier applications |
| EP1879606B1 (en) | 2005-04-25 | 2013-06-12 | Massachusetts Institute of Technology | Self-assembling peptides for promoting hemostasis |
| JP4982841B2 (ja) | 2005-10-12 | 2012-07-25 | 国立大学法人名古屋大学 | 再生医療骨組成物 |
| WO2007070645A2 (en) | 2005-12-14 | 2007-06-21 | Massachusetts Institute Of Technology | Bio-sensitized solar cells (bssc) |
| DK2012842T3 (en) | 2006-04-25 | 2018-05-28 | Massachusetts Inst Technology | COMPOSITIONS AND PROCEDURES TO INFLUENCE THE MOVEMENT OF CONTAMINANTS, BODIES, OR OTHER UNITS AND / OR TO INFLUENCE OTHER PHYSIOLOGICAL CONDITIONS |
| JP5496671B2 (ja) | 2006-09-26 | 2014-05-21 | マサチューセッツ インスティテュート オブ テクノロジー | 修飾自己組織化ペプチド |
| US9012404B2 (en) | 2006-12-11 | 2015-04-21 | 3D Matrix, Inc. | Compositions and methods for cardiac tissue protection and regeneration |
| US9415084B2 (en) | 2007-03-14 | 2016-08-16 | Arch Biosurgery, Inc. | Treatment of leaky or damaged tight junctions and enhancing extracellular matrix |
| US20090069547A1 (en) | 2007-05-01 | 2009-03-12 | Massachusetts Institute Of Technology | Stabilization of mammalian membrane proteins by short surfactant peptides |
| WO2008136820A1 (en) | 2007-05-01 | 2008-11-13 | Massachusetts Institute Of Technology | Stabilization of mammalian membrane proteins by short surfactant peptides |
| US9714941B2 (en) | 2007-07-31 | 2017-07-25 | Massachusetts Institute Of Technology | Bio-sensing nanodevice |
| WO2010014903A1 (en) | 2008-07-31 | 2010-02-04 | Massachusetts Institute Of Technology | Multiplexed olfactory receptor-based microsurface plasmon polariton detector |
| SG193822A1 (en) | 2008-08-27 | 2013-10-30 | 3 D Matrix Ltd | Transfection agent |
| KR101670099B1 (ko) | 2008-10-06 | 2016-10-27 | 가부시끼가이샤 쓰리디 매트릭스 | 조직 폐색제 |
| CN101514225B (zh) | 2008-10-13 | 2011-09-14 | 西安蓝晶生物科技有限公司 | 自聚体多肽及其制备方法和应用 |
| JP2010222338A (ja) * | 2009-02-27 | 2010-10-07 | Three D Matrix:Kk | 核酸移送担体 |
| EP2664321B1 (en) * | 2009-10-26 | 2018-08-22 | Nissan Chemical Industries, Ltd. | Medical instrument and preparation comprising a lipid peptide and gum arabic |
| US9439941B2 (en) | 2009-12-14 | 2016-09-13 | The University Of Hong Kong | Nano cancer barrier device (NCBD) to immobilize and inhibit the division of metastic cancer stem cells |
| JP2011126855A (ja) | 2009-12-15 | 2011-06-30 | Three D Matrix:Kk | タンパク質の凝集抑制剤 |
| US20130236891A1 (en) | 2010-08-20 | 2013-09-12 | 3-D Matrix, Ltd. | Method and composition for the treatment, prevention, and diagnosis of cancer containing or derived from cancer stem cells |
| US9149511B2 (en) | 2011-06-30 | 2015-10-06 | Ethicon, Inc. | Procoagulant peptides and their derivatives and uses therefor |
| CA2874003A1 (en) | 2012-05-31 | 2013-12-05 | Sotirios KOUTSOPOULOS | Sustained delivery of molecules using peptide surfactants and uses thereof |
| GB2503701B (en) | 2012-07-04 | 2015-08-26 | Shameem Anthony Carl Sampath | Limb exercise device |
| EP2869903B1 (en) | 2012-07-06 | 2018-11-28 | 3-D Matrix Ltd. | Fill-finish process for peptide solutions |
| US9140677B2 (en) | 2012-08-13 | 2015-09-22 | Massachusetts Institute Of Technology | Methods and apparatus for artificial olfaction |
| WO2014136081A1 (en) | 2013-03-06 | 2014-09-12 | 3D-Matrix Ltd. | Surgical methods employing purified amphiphilic peptide compositions |
| ES2756531T3 (es) | 2013-08-22 | 2020-04-27 | Arch Biosurgery Inc | Mallas implantables para controlar el movimiento de fluidos |
| AU2015229549B2 (en) | 2014-03-10 | 2019-05-23 | 3-D Matrix, Ltd. | Self-assembling peptide compositions |
| ES2712608T3 (es) | 2014-03-10 | 2019-05-14 | 3 D Matrix Ltd | Péptidos autoensamblantes para el tratamiento de las bullas pulmonares |
| WO2015136370A2 (en) | 2014-03-10 | 2015-09-17 | 3-D Matrix, Ltd. | Sterilization and filtration of peptide compositions |
| EP3116523B1 (en) | 2014-03-10 | 2018-10-17 | 3-D Matrix, Ltd. | Self-assembling peptides as bronchial obstruction agents |
| WO2015138473A1 (en) | 2014-03-10 | 2015-09-17 | 3-D Matrix, Ltd. | Autoassembling peptides for the treatment of pulmonary leakage |
| PL229030B1 (pl) | 2014-03-13 | 2018-05-30 | Zygmunt Jerzy Szymański | Nanopreparat bakteriobójczy |
| JP2014208669A (ja) | 2014-06-17 | 2014-11-06 | 株式会社スリー・ディー・マトリックス | タンパク質の凝集抑制剤 |
| JP2016028102A (ja) | 2015-10-21 | 2016-02-25 | 株式会社スリー・ディー・マトリックス | タンパク質の凝集抑制剤 |
| US10814038B2 (en) | 2016-01-06 | 2020-10-27 | 3-D Matrix, Ltd. | Combination compositions |
| WO2017164334A1 (ja) | 2016-03-23 | 2017-09-28 | 公益財団法人 川崎市産業振興財団 | ホウ素クラスター結合ペプチド化合物 |
| CN110198740B (zh) | 2016-11-25 | 2022-03-04 | 株式会社粒子线医疗研究所 | 用于硼中子捕获疗法的新的bsh复合体 |
| CN111405901B (zh) | 2017-11-09 | 2025-09-09 | 普瑞克斯治疗公司 | 含有miRNA的癌症治疗用医药组合物 |
| CN117085140A (zh) | 2017-12-15 | 2023-11-21 | 立美基股份有限公司 | 表面活性剂肽纳米结构及在药物递送中的用途 |
-
2018
- 2018-11-30 CN CN202311055643.1A patent/CN117085140A/zh active Pending
- 2018-11-30 US US16/206,319 patent/US11324703B2/en active Active
- 2018-11-30 WO PCT/IB2018/001511 patent/WO2019116092A1/en not_active Ceased
- 2018-11-30 JP JP2020532820A patent/JP2021506815A/ja active Pending
- 2018-11-30 EP EP18842720.7A patent/EP3723726A1/en not_active Withdrawn
- 2018-11-30 CN CN201880089258.XA patent/CN111712230B/zh active Active
-
2020
- 2020-06-15 IL IL275380A patent/IL275380A/en unknown
-
2022
- 2022-04-17 US US17/722,357 patent/US12239744B2/en active Active
-
2023
- 2023-04-06 JP JP2023062404A patent/JP7760174B2/ja active Active
-
2024
- 2024-11-22 JP JP2024204161A patent/JP2025028940A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20190231706A1 (en) | 2019-08-01 |
| JP2025028940A (ja) | 2025-03-05 |
| JP7760174B2 (ja) | 2025-10-27 |
| EP3723726A1 (en) | 2020-10-21 |
| CN111712230A (zh) | 2020-09-25 |
| JP2023076699A (ja) | 2023-06-01 |
| CN111712230B (zh) | 2024-04-26 |
| JP2021506815A (ja) | 2021-02-22 |
| CN117085140A (zh) | 2023-11-21 |
| WO2019116092A1 (en) | 2019-06-20 |
| US11324703B2 (en) | 2022-05-10 |
| US20220249392A1 (en) | 2022-08-11 |
| US12239744B2 (en) | 2025-03-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL274718A (en) | Eye preparation and device for administering it | |
| EP3922279B8 (en) | Drug delivery compositions and uses thereof | |
| IL266921A (en) | 3d printing and drug delivery | |
| SG11202003320SA (en) | Dihydropyrimidine compounds and uses thereof in medicine | |
| GB201704211D0 (en) | Ophthalmic delivery device and ophthalmic drug compositions | |
| IL246706B (en) | Fast-acting insulin preparations and pharmaceutical delivery systems | |
| PT3432970T (pt) | Dispositivos de administração de fármaco in vivo | |
| GB201522548D0 (en) | Improvements in drug delivery | |
| MX2017003638A (es) | Microparticulas inyectables para liberacion hiper-localizada de agentes terapeuticos. | |
| IL273713A (en) | Drug administration systems and related methods | |
| GB201619561D0 (en) | Medicament delivery device and system | |
| GB2563875B (en) | Improvements in drug delivery | |
| SG11201705759SA (en) | Cytotoxic hexim1 peptides and uses thereof | |
| IL265677A (en) | Formulation of a controlled-release ophthalmic drug and its uses | |
| GB201604213D0 (en) | Drug combination and its use in therapy | |
| IL275380A (en) | Surfactant peptide nanostructures and uses in drug delivery | |
| GB2561132B (en) | Systems and methods of assisting in the delivery of products | |
| AU362165S (en) | Drug delivery device | |
| EP3288544A4 (en) | Hypromellose-graft-chitosan and methods thereof for sustained drug delivery | |
| ZA201802537B (en) | Highly stable non-vesicular nanoparticles and application thereof in treating microbial infection | |
| IL255229A (en) | Anionic nanoparticles for use in the delivery of anionic small molecule drugs | |
| GB201611639D0 (en) | Delivery device and formulation | |
| GB201604639D0 (en) | Chlorhexidine crystal forms and uses thereof in medicine | |
| GB2580569B (en) | Improvements in drug delivery | |
| GB201912318D0 (en) | Improvements in drug delivery |