IL267958B2 - Composition for injection which can be used for treatment of heart diseases and contains fibroblasts, and method for producing fibroblast for therapy use - Google Patents
Composition for injection which can be used for treatment of heart diseases and contains fibroblasts, and method for producing fibroblast for therapy useInfo
- Publication number
- IL267958B2 IL267958B2 IL267958A IL26795819A IL267958B2 IL 267958 B2 IL267958 B2 IL 267958B2 IL 267958 A IL267958 A IL 267958A IL 26795819 A IL26795819 A IL 26795819A IL 267958 B2 IL267958 B2 IL 267958B2
- Authority
- IL
- Israel
- Prior art keywords
- fibroblasts
- cells
- cell
- positive
- cardiac
- Prior art date
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/33—Fibroblasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
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| JP2017033624 | 2017-02-24 | ||
| PCT/JP2018/006795 WO2018155651A1 (ja) | 2017-02-24 | 2018-02-23 | 線維芽細胞を含む心臓疾患を治療するための注射用組成物、及び治療用線維芽細胞の製造方法 |
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| IL267958A IL267958A (en) | 2019-09-26 |
| IL267958B1 IL267958B1 (en) | 2023-04-01 |
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| CA3110831A1 (en) | 2018-08-29 | 2020-03-05 | Metcela Inc. | Method for producing fibroblast, and g-csf-positive fibroblast mass |
| CN109589337B (zh) | 2018-12-29 | 2022-04-26 | 南京艾尔普再生医学科技有限公司 | 心肌细胞制剂及其制备方法和应用 |
| IL296125A (en) | 2020-03-04 | 2022-11-01 | Metcela Inc | Fibroblasts have an increased ability to produce erythropoietin |
| AU2022231584A1 (en) * | 2021-03-04 | 2023-09-07 | Lymphogenix Limited | Lymphangiogenesis promoting factor-expressing fibroblast, and pharmaceutical composition containing same |
| US20240316113A1 (en) * | 2021-09-08 | 2024-09-26 | Metcela Inc. | Fibroblast-containing pharmaceutical composition for treating kidney disease |
| EP4249585A1 (en) * | 2022-03-25 | 2023-09-27 | Technische Universität München - TUM | Heart tissue models, method of producing heart tissue models and uses of heart tissue models |
Citations (2)
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| US20060057124A1 (en) * | 2004-08-26 | 2006-03-16 | Shim Winston S N | Methods and compositions for culturing cardiomyocyte-like cells |
| JP2016027797A (ja) * | 2014-07-11 | 2016-02-25 | 貴紘 岩宮 | 心臓細胞培養材料 |
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| AU2003901668A0 (en) * | 2003-03-28 | 2003-05-01 | Medvet Science Pty. Ltd. | Non-haemopoietic precursor cells |
| CA2487254A1 (en) * | 2002-05-08 | 2003-11-20 | The Regents Of The University Of California | System and method for treating cardiac arrhythmias with fibroblast cells |
| AU2003239418B2 (en) * | 2002-05-08 | 2008-01-31 | The Regents Of The University Of California | System and method for forming a non-ablative cardiac conduction block |
| US20040161412A1 (en) * | 2002-08-22 | 2004-08-19 | The Cleveland Clinic Foundation | Cell-based VEGF delivery |
| US7470538B2 (en) * | 2002-12-05 | 2008-12-30 | Case Western Reserve University | Cell-based therapies for ischemia |
| CN101415458A (zh) * | 2003-11-10 | 2009-04-22 | 辛弗尼医药有限公司 | 控制心房纤维性颤动患者心室律的方法 |
| ES2325715B1 (es) * | 2007-08-03 | 2010-06-17 | Genetrix, S.L. | Poblacion de celulas madre adultas derivadas de tejido adiposo cardiaco y su uso en regeneracion cardiaca. |
| JP5378743B2 (ja) | 2008-09-30 | 2013-12-25 | テルモ株式会社 | 医療用細胞シートの製造方法 |
| WO2013028968A1 (en) * | 2011-08-25 | 2013-02-28 | Wisconsin Alumni Research Foundation | 3-dimensional cardiac fibroblast derived extracellular matrix |
| EP2826855B1 (en) | 2012-03-15 | 2018-08-29 | iHeart Japan Corporation | Myocardial sheet |
| US20140072611A1 (en) * | 2012-09-07 | 2014-03-13 | Fibrocell Technologies, Inc. | Methods and Compositions for Treating Post-Cardial Infarction Damage |
| GB201309057D0 (en) * | 2013-05-20 | 2013-07-03 | Cell Therapy Ltd | Method |
| KR20150009655A (ko) * | 2013-07-16 | 2015-01-27 | 학교법인 동아학숙 | Gcp-2 유전자를 과발현하는 지방 간엽줄기세포를 포함하는 허혈성 질환 치료용 조성물 |
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2018
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2021
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060057124A1 (en) * | 2004-08-26 | 2006-03-16 | Shim Winston S N | Methods and compositions for culturing cardiomyocyte-like cells |
| JP2016027797A (ja) * | 2014-07-11 | 2016-02-25 | 貴紘 岩宮 | 心臓細胞培養材料 |
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| EP3476395A4 (en) | 2020-02-26 |
| SG11201900810WA (en) | 2019-02-27 |
| CN109890398B (zh) | 2024-01-16 |
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| IL267958A (en) | 2019-09-26 |
| AU2018223739A1 (en) | 2019-02-14 |
| US20210346436A1 (en) | 2021-11-11 |
| EP3476395A1 (en) | 2019-05-01 |
| CA3032654A1 (en) | 2018-08-30 |
| JP7072135B2 (ja) | 2022-05-20 |
| IL267958B1 (en) | 2023-04-01 |
| EP3476395B1 (en) | 2021-07-21 |
| WO2018155651A1 (ja) | 2018-08-30 |
| DK3476395T3 (da) | 2021-08-16 |
| JP2019218408A (ja) | 2019-12-26 |
| JP6618066B2 (ja) | 2019-12-11 |
| US20190224250A1 (en) | 2019-07-25 |
| KR20190117468A (ko) | 2019-10-16 |
| US11096969B2 (en) | 2021-08-24 |
| AU2018223739B2 (en) | 2023-06-22 |
| KR102407387B1 (ko) | 2022-06-10 |
| JPWO2018155651A1 (ja) | 2019-11-07 |
| ES2885080T3 (es) | 2021-12-13 |
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