IL265342B2 - Use of pridofidine for the treatment of Rett syndrome - Google Patents
Use of pridofidine for the treatment of Rett syndromeInfo
- Publication number
- IL265342B2 IL265342B2 IL265342A IL26534219A IL265342B2 IL 265342 B2 IL265342 B2 IL 265342B2 IL 265342 A IL265342 A IL 265342A IL 26534219 A IL26534219 A IL 26534219A IL 265342 B2 IL265342 B2 IL 265342B2
- Authority
- IL
- Israel
- Prior art keywords
- pridopidine
- composition
- subject
- bdnf
- administered
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662395854P | 2016-09-16 | 2016-09-16 | |
| PCT/US2017/051803 WO2018053280A1 (en) | 2016-09-16 | 2017-09-15 | Use of pridopidine for treating rett syndrome |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL265342A IL265342A (en) | 2019-05-30 |
| IL265342B2 true IL265342B2 (en) | 2023-06-01 |
Family
ID=61619744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL265342A IL265342B2 (en) | 2016-09-16 | 2019-03-13 | Use of pridofidine for the treatment of Rett syndrome |
Country Status (13)
| Country | Link |
|---|---|
| EP (2) | EP3512506B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6977029B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN109982686A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2017326013B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112019005040A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3036984C (cg-RX-API-DMAC7.html) |
| DK (2) | DK4005570T3 (cg-RX-API-DMAC7.html) |
| ES (2) | ES2909557T3 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE058314T2 (cg-RX-API-DMAC7.html) |
| IL (1) | IL265342B2 (cg-RX-API-DMAC7.html) |
| MX (1) | MX388845B (cg-RX-API-DMAC7.html) |
| PL (2) | PL3512506T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2018053280A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA122999C2 (uk) | 2013-06-21 | 2021-02-03 | Прайлінія Н'Юротерапьютікс Лтд. | Застосування придопідину для лікування хвороби гантінгтона |
| US11090297B2 (en) | 2013-06-21 | 2021-08-17 | Prilenia Neurotherapeutics Ltd. | Pridopidine for treating huntington's disease |
| EP3503890B1 (en) | 2016-08-24 | 2024-12-18 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine for treating dystonias |
| MX390627B (es) | 2016-08-24 | 2025-03-21 | Prilenia Neurotherapeutics Ltd | Uso de pridopidina para el tratamiento de la disminucion funcional. |
| US12102627B2 (en) | 2016-09-16 | 2024-10-01 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine for treating rett syndrome |
| CN109982686A (zh) | 2016-09-16 | 2019-07-05 | 普瑞尼亚医疗发展有限公司 | 普利多匹定用于治疗rett综合征的用途 |
| US12036213B2 (en) | 2017-09-08 | 2024-07-16 | Prilenia Neurotherapeutics Ltd. | Pridopidine for treating drug induced dyskinesias |
| BR112021015346A2 (pt) | 2019-02-04 | 2021-10-05 | Prilenia Neurotherapeutics Ltd. | Uso de pridopidina de baixa dose para a doença de parkinson e outras doenças associadas ao parkinsonismo |
| CN116472043A (zh) * | 2020-10-20 | 2023-07-21 | 普瑞尼亚神经治疗有限公司 | 普利多匹定和类似物用于治疗焦虑和抑郁的用途 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001046145A1 (en) * | 1999-12-22 | 2001-06-28 | A. Carlsson Research Ab | New modulators of dopamine neurotransmission |
| WO2013086425A1 (en) * | 2011-12-08 | 2013-06-13 | IVAX International GmbH | The hydrobromide salt of pridopidine |
| WO2015112601A1 (en) * | 2014-01-22 | 2015-07-30 | IVAX International GmbH | Modified release formulations of pridopidine |
| WO2016138135A1 (en) * | 2015-02-25 | 2016-09-01 | Teva Pharmaceuticals International Gmbh | Sigma-1 receptor modulators for treating huntington's disease |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2584831C (en) | 2004-10-13 | 2013-09-17 | Neurosearch Sweden Ab | Process for the synthesis of 4-(3-methanesulfonylphenyl)-1-n-propyl-piperidine |
| JP2013536825A (ja) | 2010-09-03 | 2013-09-26 | イバックス・インターナショナル・ゲーエムベーハー | ドパミン作動性安定化剤として有用なプリドピジンの重水素化類似体 |
| US20130267552A1 (en) | 2012-04-04 | 2013-10-10 | IVAX International GmbH | Pharmaceutical compositions for combination therapy |
| UA122999C2 (uk) | 2013-06-21 | 2021-02-03 | Прайлінія Н'Юротерапьютікс Лтд. | Застосування придопідину для лікування хвороби гантінгтона |
| EP4282479A3 (en) * | 2015-02-25 | 2024-02-21 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine to treat depression or anxiety |
| CN109982686A (zh) | 2016-09-16 | 2019-07-05 | 普瑞尼亚医疗发展有限公司 | 普利多匹定用于治疗rett综合征的用途 |
-
2017
- 2017-09-15 CN CN201780071045.XA patent/CN109982686A/zh active Pending
- 2017-09-15 DK DK22150695.9T patent/DK4005570T3/da active
- 2017-09-15 CA CA3036984A patent/CA3036984C/en active Active
- 2017-09-15 DK DK17851614.2T patent/DK3512506T3/da active
- 2017-09-15 AU AU2017326013A patent/AU2017326013B2/en active Active
- 2017-09-15 ES ES17851614T patent/ES2909557T3/es active Active
- 2017-09-15 JP JP2019514217A patent/JP6977029B2/ja active Active
- 2017-09-15 HU HUE17851614A patent/HUE058314T2/hu unknown
- 2017-09-15 EP EP17851614.2A patent/EP3512506B1/en active Active
- 2017-09-15 MX MX2019003069A patent/MX388845B/es unknown
- 2017-09-15 WO PCT/US2017/051803 patent/WO2018053280A1/en not_active Ceased
- 2017-09-15 BR BR112019005040A patent/BR112019005040A2/pt not_active Application Discontinuation
- 2017-09-15 PL PL17851614T patent/PL3512506T3/pl unknown
- 2017-09-15 PL PL22150695.9T patent/PL4005570T3/pl unknown
- 2017-09-15 ES ES22150695T patent/ES2986807T3/es active Active
- 2017-09-15 EP EP22150695.9A patent/EP4005570B1/en active Active
-
2019
- 2019-03-13 IL IL265342A patent/IL265342B2/en unknown
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001046145A1 (en) * | 1999-12-22 | 2001-06-28 | A. Carlsson Research Ab | New modulators of dopamine neurotransmission |
| WO2013086425A1 (en) * | 2011-12-08 | 2013-06-13 | IVAX International GmbH | The hydrobromide salt of pridopidine |
| WO2015112601A1 (en) * | 2014-01-22 | 2015-07-30 | IVAX International GmbH | Modified release formulations of pridopidine |
| WO2016138135A1 (en) * | 2015-02-25 | 2016-09-01 | Teva Pharmaceuticals International Gmbh | Sigma-1 receptor modulators for treating huntington's disease |
Non-Patent Citations (1)
| Title |
|---|
| LI W ET AL., BDNF DEREGULATION IN RETT SYNDROME, 15 April 2013 (2013-04-15) * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN109982686A (zh) | 2019-07-05 |
| JP2019532926A (ja) | 2019-11-14 |
| MX388845B (es) | 2025-03-20 |
| ES2909557T3 (es) | 2022-05-09 |
| ES2986807T3 (es) | 2024-11-12 |
| PL4005570T3 (pl) | 2024-09-23 |
| IL265342A (en) | 2019-05-30 |
| AU2017326013B2 (en) | 2020-12-24 |
| DK3512506T3 (da) | 2022-04-19 |
| DK4005570T3 (da) | 2024-08-19 |
| AU2017326013A1 (en) | 2019-04-11 |
| EP3512506A1 (en) | 2019-07-24 |
| EP4005570A1 (en) | 2022-06-01 |
| MX2019003069A (es) | 2019-09-02 |
| CA3036984C (en) | 2023-07-18 |
| HUE058314T2 (hu) | 2022-07-28 |
| PL3512506T3 (pl) | 2022-05-30 |
| JP6977029B2 (ja) | 2021-12-08 |
| WO2018053280A1 (en) | 2018-03-22 |
| CA3036984A1 (en) | 2018-03-22 |
| EP3512506A4 (en) | 2020-05-27 |
| EP4005570B1 (en) | 2024-05-15 |
| EP3512506B1 (en) | 2022-01-26 |
| BR112019005040A2 (pt) | 2019-07-16 |
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