IL264640A - - Google Patents

Info

Publication number
IL264640A
IL264640A IL26464019A IL26464019A IL264640A IL 264640 A IL264640 A IL 264640A IL 26464019 A IL26464019 A IL 26464019A IL 26464019 A IL26464019 A IL 26464019A IL 264640 A IL264640 A IL 264640A
Authority
IL
Israel
Application number
IL26464019A
Other languages
English (en)
Other versions
IL264640B1 (en
IL264640B2 (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of IL264640A publication Critical patent/IL264640A/en
Publication of IL264640B1 publication Critical patent/IL264640B1/en
Publication of IL264640B2 publication Critical patent/IL264640B2/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845Methods of identifying protein-protein interactions in protein mixtures
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587Nanoparticles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N2021/258Surface plasmon spectroscopy, e.g. micro- or nanoparticles in suspension

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
IL264640A 2016-08-18 2017-08-18 Assay for determining potential to self-association of a protein using concentration-dependent self-interaction nanoparticle spectroscopy IL264640B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662376788P 2016-08-18 2016-08-18
PCT/US2017/047630 WO2018035470A1 (en) 2016-08-18 2017-08-18 Assay for determining potential to self-association of a protein using concentration-dependent self-interaction nanoparticle spectroscopy

Publications (3)

Publication Number Publication Date
IL264640A true IL264640A (https=) 2019-04-30
IL264640B1 IL264640B1 (en) 2023-11-01
IL264640B2 IL264640B2 (en) 2024-03-01

Family

ID=59746357

Family Applications (2)

Application Number Title Priority Date Filing Date
IL264640A IL264640B2 (en) 2016-08-18 2017-08-18 Assay for determining potential to self-association of a protein using concentration-dependent self-interaction nanoparticle spectroscopy
IL307435A IL307435A (en) 2016-08-18 2017-08-18 A test to determine concentration-dependent self-interaction

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL307435A IL307435A (en) 2016-08-18 2017-08-18 A test to determine concentration-dependent self-interaction

Country Status (19)

Country Link
US (3) US11428695B2 (https=)
EP (2) EP3500856B1 (https=)
JP (3) JP6959327B2 (https=)
KR (3) KR102717462B1 (https=)
CN (2) CN115468919A (https=)
AU (2) AU2017313150B2 (https=)
BR (1) BR112019003175A2 (https=)
CA (3) CA3254461A1 (https=)
DK (2) DK3500856T3 (https=)
EA (1) EA201990316A1 (https=)
ES (2) ES2837093T3 (https=)
FI (1) FI3761035T3 (https=)
HU (2) HUE052805T2 (https=)
IL (2) IL264640B2 (https=)
MX (2) MX2019001930A (https=)
PL (2) PL3500856T3 (https=)
SG (1) SG11201900895QA (https=)
WO (1) WO2018035470A1 (https=)
ZA (1) ZA201901035B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3500856T3 (da) 2016-08-18 2020-12-14 Regeneron Pharma Assay til bestemmelse af et proteins potentiale for at selvassociere ved hjælp af koncentrationsafhængig selvinteraktionsnanopartikelspektroskopi
US11103552B2 (en) 2018-05-10 2021-08-31 Regeneron Pharmaceuticals, Inc. High concentration VEGF receptor fusion protein containing formulations
CN113588582B (zh) * 2020-04-30 2024-05-14 上海药明生物技术有限公司 蛋白质样品浓度测定方式选择法及测定方法
WO2023095154A1 (en) * 2021-11-24 2023-06-01 Sensoville Biotech Pvt Ltd Method for determining changes in a protein's structure
WO2023141319A1 (en) * 2022-01-24 2023-07-27 Amgen Inc. Methods for detecting antibody self-association
CN119832975A (zh) * 2024-12-24 2025-04-15 上海药明生物技术有限公司 一种蛋白质共处方制剂的稳定性预测方法

Family Cites Families (25)

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US771997A (en) 1903-11-21 1904-10-11 Alfred Palm Lathe attachment.
US4254102A (en) * 1975-09-08 1981-03-03 Plough, Inc. Substantive PABA compositions
US4080264A (en) 1976-03-01 1978-03-21 Massachusetts Institute Of Technology Immunoassay by light scattering spectroscopy
US6927044B2 (en) 1998-09-25 2005-08-09 Regeneron Pharmaceuticals, Inc. IL-1 receptor based cytokine traps
US7087411B2 (en) 1999-06-08 2006-08-08 Regeneron Pharmaceuticals, Inc. Fusion protein capable of binding VEGF
US20050214356A1 (en) * 2004-03-24 2005-09-29 Joyce Timothy H Self assembling activation agents targeted using active drug release
US20050221507A1 (en) * 2004-03-30 2005-10-06 Intel Corporation Method to detect molecular binding by surface-enhanced Raman spectroscopy
US7514938B2 (en) 2004-05-11 2009-04-07 Board Of Regents Of The University And College System Of Nevada, On Behalf Of The University Of Nevada, Reno Dielectric relaxation spectroscopy apparatus and methods of use
TW200621282A (en) 2004-08-13 2006-07-01 Wyeth Corp Stabilizing formulations
CN101238141B (zh) * 2005-05-02 2016-10-12 巴斯福股份公司 灵敏检测分析物的新标记策略
WO2007121363A2 (en) 2006-04-13 2007-10-25 Mississippi State University An optical apparatus for simultaneously measuring the scattering and concentration signals of macromolecules in a flow cell
EP2076287A2 (en) 2006-10-12 2009-07-08 Wyeth Methods and compositions with reduced opalescence
GB0621050D0 (en) * 2006-10-23 2006-11-29 Univ Strathclyde Functionalised polymers for labelling metal surfaces
WO2008151219A1 (en) 2007-06-04 2008-12-11 Regeneron Pharmaceuticals, Inc. Enhanced expression and stability regions
US20090104114A1 (en) * 2007-09-21 2009-04-23 Cytimmune Sciences, Inc. Nanotherapeutic Colloidal Metal Compositions and Methods
US20110305765A1 (en) * 2008-11-21 2011-12-15 Board Of Regents, The University Of Texas System Preparation and methodology of silk fibroin nanoparticles
US20140024024A1 (en) * 2012-07-17 2014-01-23 General Electric Company Methods of detecting dna, rna and protein in biological samples
WO2014192937A1 (ja) * 2013-05-30 2014-12-04 公立大学法人大阪府立大学 被検出物質の検出装置および方法
IL312865B2 (en) * 2013-09-11 2025-06-01 Eagle Biologics Inc Liquid protein formulations containing viscosity-lowering agents
EP2902503A1 (en) * 2014-01-31 2015-08-05 Fundación Imdea Nanociencia Functionalized metal nanoparticles and uses thereof for detecting nucleic acids
WO2015196091A1 (en) * 2014-06-20 2015-12-23 Reform Biologics, Llc Viscosity-reducing excipient compounds for protein formulations
CN104062287B (zh) 2014-07-01 2017-08-08 福建工程学院 一种基于纳米金催化的化学发光分析检测铁蛋白的方法
MA40861A (fr) 2014-10-31 2017-09-05 Biogen Ma Inc Anticorps anti-glycoprotéines iib/iiia
WO2016115475A1 (en) * 2015-01-18 2016-07-21 Biogen Ma Inc. Anti-cd40 antibody formulations
DK3500856T3 (da) 2016-08-18 2020-12-14 Regeneron Pharma Assay til bestemmelse af et proteins potentiale for at selvassociere ved hjælp af koncentrationsafhængig selvinteraktionsnanopartikelspektroskopi

Also Published As

Publication number Publication date
US20240280582A1 (en) 2024-08-22
SG11201900895QA (en) 2019-02-27
DK3761035T3 (da) 2024-03-11
JP2019532267A (ja) 2019-11-07
EP3761035A1 (en) 2021-01-06
IL264640B1 (en) 2023-11-01
AU2017313150B2 (en) 2023-09-14
US11428695B2 (en) 2022-08-30
JP6959327B2 (ja) 2021-11-02
MX2023013583A (es) 2023-11-30
IL307435A (en) 2023-12-01
CA3254460A1 (en) 2025-07-03
ZA201901035B (en) 2024-06-26
US20190187149A1 (en) 2019-06-20
EA201990316A1 (ru) 2019-07-31
KR20190039185A (ko) 2019-04-10
WO2018035470A9 (en) 2018-07-05
CN115468919A (zh) 2022-12-13
EP3500856A1 (en) 2019-06-26
JP2023139189A (ja) 2023-10-03
ES2837093T3 (es) 2021-06-29
CA3254461A1 (en) 2025-07-03
EP3761035B1 (en) 2024-02-14
JP2022008959A (ja) 2022-01-14
DK3500856T3 (da) 2020-12-14
WO2018035470A1 (en) 2018-02-22
CA3032361C (en) 2025-07-08
HUE066064T2 (hu) 2024-07-28
MX2019001930A (es) 2019-07-04
JP7321227B2 (ja) 2023-08-04
CA3032361A1 (en) 2018-02-22
AU2017313150A1 (en) 2019-02-21
US11988668B2 (en) 2024-05-21
IL264640B2 (en) 2024-03-01
CN109661577B (zh) 2022-09-27
KR102534506B1 (ko) 2023-05-30
CN109661577A (zh) 2019-04-19
PL3761035T3 (pl) 2024-06-24
KR20220126801A (ko) 2022-09-16
ES2974961T3 (es) 2024-07-02
PL3500856T3 (pl) 2021-04-19
KR102717462B1 (ko) 2024-10-16
KR20230074614A (ko) 2023-05-30
BR112019003175A2 (pt) 2019-06-18
HUE052805T2 (hu) 2021-05-28
AU2023274236A1 (en) 2023-12-21
EP3500856B1 (en) 2020-10-07
FI3761035T3 (fi) 2024-03-18
US20220357335A1 (en) 2022-11-10
KR102441221B1 (ko) 2022-09-07

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