IL239213B - Preparations and methods for capturing cellular targets of biologically active substances - Google Patents
Preparations and methods for capturing cellular targets of biologically active substancesInfo
- Publication number
- IL239213B IL239213B IL239213A IL23921315A IL239213B IL 239213 B IL239213 B IL 239213B IL 239213 A IL239213 A IL 239213A IL 23921315 A IL23921315 A IL 23921315A IL 239213 B IL239213 B IL 239213B
- Authority
- IL
- Israel
- Prior art keywords
- bioactiv
- capture
- agents
- compositions
- methods
- Prior art date
Links
- 230000001413 cellular effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261736426P | 2012-12-12 | 2012-12-12 | |
| US201361788313P | 2013-03-15 | 2013-03-15 | |
| PCT/US2013/074756 WO2014093671A1 (en) | 2012-12-12 | 2013-12-12 | Compositions and methods for capture of cellular targets of bioactive agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL239213A0 IL239213A0 (en) | 2015-07-30 |
| IL239213B true IL239213B (en) | 2020-03-31 |
Family
ID=50934961
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL239213A IL239213B (en) | 2012-12-12 | 2015-06-04 | Preparations and methods for capturing cellular targets of biologically active substances |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9551705B2 (OSRAM) |
| EP (1) | EP2931305B1 (OSRAM) |
| JP (2) | JP6484178B2 (OSRAM) |
| KR (2) | KR102272233B1 (OSRAM) |
| CN (1) | CN104853767B (OSRAM) |
| AU (2) | AU2013359160B2 (OSRAM) |
| BR (1) | BR112015013715A2 (OSRAM) |
| CA (1) | CA2894432C (OSRAM) |
| IL (1) | IL239213B (OSRAM) |
| SG (1) | SG11201504520XA (OSRAM) |
| WO (1) | WO2014093671A1 (OSRAM) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102652175B (zh) | 2009-12-09 | 2016-02-10 | 宝洁公司 | 织物和家居护理产品 |
| JP6522339B2 (ja) * | 2011-11-21 | 2019-05-29 | プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ | カルボキシｘローダミン類似体 |
| KR102272233B1 (ko) | 2012-12-12 | 2021-07-01 | 프로메가 코포레이션 | 생체활성 제제의 세포 표적 포획을 위한 조성물 및 방법 |
| US10168323B2 (en) | 2013-03-15 | 2019-01-01 | Promega Corporation | Compositions and methods for capture of cellular targets of bioactive agents |
| WO2014151282A1 (en) | 2013-03-15 | 2014-09-25 | Promega Corporation | Substrates for covalent tethering of proteins to functional groups or solid surfaces |
| EP3304078B1 (en) | 2015-06-05 | 2022-08-31 | Promega Corporation | Cell-permeable, cell-compatible, and cleavable linkers for covalent tethering of functional elements |
| US10458988B2 (en) * | 2017-03-03 | 2019-10-29 | Musc Foundation For Research Development | Biotinylated luminescent probe |
| US12181452B2 (en) | 2017-09-18 | 2024-12-31 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
| US12180581B2 (en) | 2017-09-18 | 2024-12-31 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
| US11709156B2 (en) | 2017-09-18 | 2023-07-25 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved analytical analysis |
| US11709155B2 (en) | 2017-09-18 | 2023-07-25 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
| JP7584433B2 (ja) | 2019-03-20 | 2024-11-15 | プロメガ コーポレイション | 光親和性プローブ |
| US11918936B2 (en) | 2020-01-17 | 2024-03-05 | Waters Technologies Corporation | Performance and dynamic range for oligonucleotide bioanalysis through reduction of non specific binding |
| EP4217730B1 (en) | 2020-09-24 | 2025-08-20 | Waters Technologies Corporation | Chromatographic hardware improvements for the separation of reactive molecules |
| JP2022182394A (ja) * | 2021-05-28 | 2022-12-08 | 独立行政法人国立病院機構 | 抗原固相化デバイス |
| WO2023287984A1 (en) * | 2021-07-14 | 2023-01-19 | University Of Maryland, Baltimore | Suberoylanilide hydroxamic acid (saha) drugs, conjugates, and nanoparticles, and methods of use thereof |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5914095A (en) | 1989-04-07 | 1999-06-22 | Salutar, Inc. | Polychelants containg amide bonds |
| EP0575955B1 (en) | 1992-06-22 | 1999-09-15 | Kyowa Hakko Kogyo Co., Ltd. | Process for producing staurosporine derivatives |
| AU5323794A (en) | 1992-10-14 | 1994-05-09 | Sterling Winthrop Inc. | Chelating polymers |
| US5756688A (en) | 1992-10-14 | 1998-05-26 | Sterling Winthrop Inc. | MR imaging compositions and methods |
| GB9503969D0 (en) | 1995-02-28 | 1995-04-19 | Sams Bernard | Incrementing mechanism |
| AU2001229741A1 (en) | 2000-01-24 | 2001-07-31 | The Trustees Of Columbia University In The City Of New York | An in vivo screen using chemical inducers of dimerization |
| US20020168737A1 (en) | 2001-01-24 | 2002-11-14 | Cornish Virginia W. | Binding and catalysis screen for high throughput determination of protein function using chemical inducers of dimerization |
| PT2357006E (pt) | 2002-07-31 | 2016-01-22 | Seattle Genetics Inc | Conjugados de fármacos e sua utilização para tratamento do cancro, de uma doença autoimune ou de uma doença infeciosa |
| AU2004211584B2 (en) | 2003-01-31 | 2009-11-12 | Promega Corporation | Covalent tethering of functional groups to proteins |
| US7429472B2 (en) | 2003-01-31 | 2008-09-30 | Promega Corporation | Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule |
| KR100507796B1 (ko) | 2003-04-03 | 2005-08-17 | 한미약품 주식회사 | 생체내 반감기가 증가된 ｐｅｇ-생리활성 폴리펩티드 동종이량체 결합체 및 이의 제조방법 |
| US7425436B2 (en) | 2004-07-30 | 2008-09-16 | Promega Corporation | Covalent tethering of functional groups to proteins and substrates therefor |
| US20070224620A1 (en) * | 2006-02-08 | 2007-09-27 | Promega Corporation | Compositions and methods for capturing and analyzing cross-linked biomolecules |
| JP5420198B2 (ja) * | 2008-06-16 | 2014-02-19 | オリンパス株式会社 | タンパク質相互作用解析方法、ポリヌクレオチド、および、組成物 |
| KR100891456B1 (ko) | 2008-11-06 | 2009-04-01 | 씨지케이 주식회사 | 생리활성물질에 대한 세포내 표적물질을 검출하는 방법 및 장치 |
| SG10201901453PA (en) | 2009-05-01 | 2019-03-28 | Promega Corp | Synthetic oplophorus luciferases with enhanced light output |
| BR112013010855A2 (pt) | 2010-11-02 | 2017-06-27 | Promega Corp | luciferases derivadas de oplophorus, novos substratos de coelenterazina e métodos de uso |
| KR102272233B1 (ko) * | 2012-12-12 | 2021-07-01 | 프로메가 코포레이션 | 생체활성 제제의 세포 표적 포획을 위한 조성물 및 방법 |
| WO2014151282A1 (en) * | 2013-03-15 | 2014-09-25 | Promega Corporation | Substrates for covalent tethering of proteins to functional groups or solid surfaces |
| US10168323B2 (en) * | 2013-03-15 | 2019-01-01 | Promega Corporation | Compositions and methods for capture of cellular targets of bioactive agents |
| EP3304078B1 (en) * | 2015-06-05 | 2022-08-31 | Promega Corporation | Cell-permeable, cell-compatible, and cleavable linkers for covalent tethering of functional elements |
-
2013
- 2013-12-12 KR KR1020207024366A patent/KR102272233B1/ko active Active
- 2013-12-12 EP EP13862430.9A patent/EP2931305B1/en active Active
- 2013-12-12 WO PCT/US2013/074756 patent/WO2014093671A1/en not_active Ceased
- 2013-12-12 AU AU2013359160A patent/AU2013359160B2/en active Active
- 2013-12-12 KR KR1020157018280A patent/KR102227321B1/ko active Active
- 2013-12-12 BR BR112015013715A patent/BR112015013715A2/pt not_active Application Discontinuation
- 2013-12-12 US US14/104,814 patent/US9551705B2/en active Active
- 2013-12-12 SG SG11201504520XA patent/SG11201504520XA/en unknown
- 2013-12-12 CA CA2894432A patent/CA2894432C/en active Active
- 2013-12-12 JP JP2015547559A patent/JP6484178B2/ja active Active
- 2013-12-12 CN CN201380064237.XA patent/CN104853767B/zh active Active
-
2015
- 2015-06-04 IL IL239213A patent/IL239213B/en active IP Right Grant
-
2017
- 2017-01-10 US US15/402,879 patent/US10976312B2/en active Active
-
2019
- 2019-02-14 AU AU2019201035A patent/AU2019201035B9/en active Active
- 2019-02-15 JP JP2019025449A patent/JP6999589B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US9551705B2 (en) | 2017-01-24 |
| CN104853767A (zh) | 2015-08-19 |
| EP2931305A1 (en) | 2015-10-21 |
| AU2013359160B2 (en) | 2018-11-15 |
| KR102272233B1 (ko) | 2021-07-01 |
| US10976312B2 (en) | 2021-04-13 |
| EP2931305B1 (en) | 2018-11-28 |
| JP6484178B2 (ja) | 2019-03-13 |
| SG11201504520XA (en) | 2015-07-30 |
| BR112015013715A2 (pt) | 2017-09-26 |
| KR102227321B1 (ko) | 2021-03-12 |
| IL239213A0 (en) | 2015-07-30 |
| JP2019092517A (ja) | 2019-06-20 |
| AU2019201035B9 (en) | 2021-02-11 |
| AU2013359160A1 (en) | 2015-07-09 |
| EP2931305A4 (en) | 2016-08-17 |
| CA2894432A1 (en) | 2014-06-19 |
| CA2894432C (en) | 2022-06-07 |
| AU2019201035B2 (en) | 2020-09-03 |
| KR20200103867A (ko) | 2020-09-02 |
| WO2014093671A1 (en) | 2014-06-19 |
| JP6999589B2 (ja) | 2022-02-04 |
| AU2013359160A2 (en) | 2015-11-12 |
| CN104853767B (zh) | 2017-04-05 |
| US20170115283A1 (en) | 2017-04-27 |
| US20140199712A1 (en) | 2014-07-17 |
| KR20150093222A (ko) | 2015-08-17 |
| AU2019201035A1 (en) | 2019-03-07 |
| JP2016502843A (ja) | 2016-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed |