IL232584B - A chimeric particle of the human papillomavirus - Google Patents
A chimeric particle of the human papillomavirusInfo
- Publication number
- IL232584B IL232584B IL232584A IL23258414A IL232584B IL 232584 B IL232584 B IL 232584B IL 232584 A IL232584 A IL 232584A IL 23258414 A IL23258414 A IL 23258414A IL 232584 B IL232584 B IL 232584B
- Authority
- IL
- Israel
- Prior art keywords
- chimaeric
- hpv
- particle
- hpv chimaeric
- chimaeric particle
- Prior art date
Links
- 239000002245 particle Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/295—Polyvalent viral antigens; Mixtures of viral and bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/01—DNA viruses
- C07K14/025—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
- C12N7/045—Pseudoviral particles; Non infectious pseudovirions, e.g. genetically engineered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20023—Virus like particles [VLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ZA201108841 | 2011-12-01 | ||
| PCT/IB2012/056912 WO2013080187A1 (en) | 2011-12-01 | 2012-12-03 | Hpv chimaeric particle |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL232584A0 IL232584A0 (en) | 2014-06-30 |
| IL232584B true IL232584B (en) | 2018-10-31 |
Family
ID=48534756
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL232584A IL232584B (en) | 2011-12-01 | 2014-05-13 | A chimeric particle of the human papillomavirus |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9771397B2 (enExample) |
| EP (1) | EP2785842A4 (enExample) |
| JP (1) | JP6228922B2 (enExample) |
| KR (1) | KR102013801B1 (enExample) |
| CN (1) | CN103890177B (enExample) |
| AU (1) | AU2012345443B2 (enExample) |
| BR (1) | BR112014012491A2 (enExample) |
| CA (1) | CA2850293C (enExample) |
| HK (1) | HK1198703A1 (enExample) |
| IL (1) | IL232584B (enExample) |
| IN (1) | IN2014DN03054A (enExample) |
| MX (1) | MX355352B (enExample) |
| MY (1) | MY184076A (enExample) |
| PH (1) | PH12014500466A1 (enExample) |
| RU (1) | RU2642287C2 (enExample) |
| SG (1) | SG11201401579UA (enExample) |
| WO (1) | WO2013080187A1 (enExample) |
| ZA (1) | ZA201403557B (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107252489A (zh) | 2009-04-13 | 2017-10-17 | 法国健康和医学研究院 | Hpv颗粒及其用途 |
| US9700639B2 (en) | 2012-02-07 | 2017-07-11 | Aura Biosciences, Inc. | Virion-derived nanospheres for selective delivery of therapeutic and diagnostic agents to cancer cells |
| MX385842B (es) * | 2013-09-18 | 2025-03-18 | Aura Biosciences Inc | Conjugados de partículas de tipo virus y uso de las mismas. |
| CN104531741B (zh) * | 2014-08-22 | 2016-08-24 | 天津康希诺生物技术有限公司 | 增强hpv抗原表位肽免疫原性的方法及类病毒颗粒、颗粒制备方法与应用 |
| CN105801704B (zh) * | 2014-12-31 | 2020-06-02 | 艾托金生物医药（苏州）有限公司 | 一种具有抗宫颈癌细胞活性的重组疫苗构建方法及应用 |
| EP3827846B1 (en) | 2015-08-18 | 2024-10-02 | Rakuten Medical, Inc. | Compositions, combinations and related methods for photoimmunotherapy |
| CN114699525A (zh) | 2015-08-18 | 2022-07-05 | 乐天医药生技股份有限公司 | 酞菁染料偶联物的制造方法及稳定偶联物 |
| AU2016343722A1 (en) | 2015-10-30 | 2018-05-24 | Aleta Biotherapeutics, Inc. | Targeted cancer therapy |
| BR112019020853A2 (pt) | 2017-04-04 | 2020-05-12 | Avidea Technologies, Inc. | Vacinas à base de peptídeo, métodos de fabricação e usos das mesmas para induzir uma resposta imune |
| MX2019015769A (es) | 2017-06-23 | 2020-08-03 | Verimmune Inc | Partículas tipo virus quiméricas y usos de estas como redireccionadores de respuestas inmunitarias específicos para el antígeno. |
| JP7641005B2 (ja) | 2018-12-27 | 2025-03-06 | ヴェリミューン インコーポレイテッド | コンジュゲート型ウイルス様粒子および抗腫瘍免疫リダイレクタとしてのその使用 |
| CA3147849A1 (en) | 2019-07-19 | 2021-01-28 | Sinocelltech Ltd. | Polyvalent immunogenicity composition for human papillomavirus |
| WO2021161179A1 (en) * | 2020-02-10 | 2021-08-19 | University Of Cape Town | Plant produced bovine papillomavirus virus-like particles and pseudovirions |
| MX2023004465A (es) | 2020-10-19 | 2023-06-19 | Verimmune Inc | Composiciones basadas en virus y métodos para redirigir respuestas inmunitarias preexistentes mediante su uso para el tratamiento del cáncer. |
| KR102821363B1 (ko) | 2023-02-06 | 2025-06-13 | 영산대학교산학협력단 | 드론에 장착된 라이다 센서를 기초로 하는 수심 측량 시스템 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9507657A (pt) * | 1994-05-16 | 1997-09-09 | Merck & Co Inc | Proteina isolada e purificada de papilomavirus recombinante capsideos particulas semelhantes a virus processos a virus processos para produzir a proteina para tratar ou prevenir a infecçao por papilomavirus para produzir uma proteina de capsideo de papilomavirus recombinante montada em um capsideo ou particula semelhante a virus e para induzir uma resposta imune em um animal vertebrado composiçoes farmacêuticas kit para a detecçao de papilomavirus ou anticorpos para papilomavirus e sistema sinte |
| PL347472A1 (en) | 1998-08-14 | 2002-04-08 | Merck & Co Inc | Process for purifying human papillomavirus virus-like particles |
| US20020016372A1 (en) * | 2000-07-31 | 2002-02-07 | Allison Anthony Clifford | Method for preventing and treating alzheimer's disease and brain damage associated with cardiov ascular disease and head injury |
| WO2003068163A2 (en) | 2002-02-14 | 2003-08-21 | Novavax, Inc. | Optimization of gene sequences of chimeric virus-like particles for expression in insect cells |
| PT1506222E (pt) | 2002-05-17 | 2009-06-12 | Univ Cape Town | Proteínas l1 quiméricas do papilomavírus humano 16 incluindo um péptido l2, partículas semelhantes a vírus preparadas a partir daquelas e um método de preparação das partículas |
| WO2006119516A2 (en) | 2005-04-29 | 2006-11-09 | University Of Cape Town | Expression of viral proteins in plants |
| CN102458440A (zh) * | 2009-04-10 | 2012-05-16 | 约翰·霍普金斯大学 | 作为广谱人类乳头状瘤病毒(hpv)疫苗的乳头状瘤病毒样颗粒(vlp) |
| AU2009348078B2 (en) | 2009-06-19 | 2013-03-14 | Eyegene Inc. | Vaccine for cervical cancer |
| PE20120563A1 (es) | 2009-06-25 | 2012-05-17 | Glaxosmithkline Biolog Sa | Construcciones novedosas de proteina del virus de papiloma humano (hpv) y su uso en la prevencion de la enfermedad por el hpv |
| WO2011077371A1 (en) * | 2009-12-22 | 2011-06-30 | University Of Cape Town | Method for enhancing the expression of hpv l1 |
-
2012
- 2012-12-03 KR KR1020147010686A patent/KR102013801B1/ko not_active Expired - Fee Related
- 2012-12-03 BR BR112014012491A patent/BR112014012491A2/pt not_active IP Right Cessation
- 2012-12-03 SG SG11201401579UA patent/SG11201401579UA/en unknown
- 2012-12-03 PH PH1/2014/500466A patent/PH12014500466A1/en unknown
- 2012-12-03 RU RU2014126587A patent/RU2642287C2/ru not_active IP Right Cessation
- 2012-12-03 MY MYPI2014700894A patent/MY184076A/en unknown
- 2012-12-03 HK HK14112143.5A patent/HK1198703A1/xx unknown
- 2012-12-03 JP JP2014544038A patent/JP6228922B2/ja not_active Expired - Fee Related
- 2012-12-03 EP EP12853360.1A patent/EP2785842A4/en not_active Withdrawn
- 2012-12-03 WO PCT/IB2012/056912 patent/WO2013080187A1/en not_active Ceased
- 2012-12-03 MX MX2014006520A patent/MX355352B/es active IP Right Grant
- 2012-12-03 CA CA2850293A patent/CA2850293C/en not_active Expired - Fee Related
- 2012-12-03 US US14/360,524 patent/US9771397B2/en not_active Expired - Fee Related
- 2012-12-03 CN CN201280052968.8A patent/CN103890177B/zh not_active Expired - Fee Related
- 2012-12-03 AU AU2012345443A patent/AU2012345443B2/en not_active Ceased
- 2012-12-03 IN IN3054DEN2014 patent/IN2014DN03054A/en unknown
-
2014
- 2014-05-13 IL IL232584A patent/IL232584B/en active IP Right Grant
- 2014-05-16 ZA ZA2014/03557A patent/ZA201403557B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PH12014500466A1 (en) | 2022-05-11 |
| BR112014012491A2 (pt) | 2017-06-06 |
| EP2785842A4 (en) | 2015-11-25 |
| NZ622595A (en) | 2016-04-29 |
| MX355352B (es) | 2018-04-17 |
| US20140377367A1 (en) | 2014-12-25 |
| MY184076A (en) | 2021-03-17 |
| JP6228922B2 (ja) | 2017-11-08 |
| IN2014DN03054A (enExample) | 2015-05-15 |
| CN103890177B (zh) | 2016-03-09 |
| CA2850293A1 (en) | 2013-06-06 |
| JP2015500229A (ja) | 2015-01-05 |
| AU2012345443A1 (en) | 2014-04-17 |
| EP2785842A1 (en) | 2014-10-08 |
| RU2014126587A (ru) | 2016-01-27 |
| IL232584A0 (en) | 2014-06-30 |
| KR20140098061A (ko) | 2014-08-07 |
| RU2642287C2 (ru) | 2018-01-24 |
| AU2012345443B2 (en) | 2017-10-26 |
| CA2850293C (en) | 2019-10-08 |
| HK1198703A1 (en) | 2015-05-29 |
| US9771397B2 (en) | 2017-09-26 |
| WO2013080187A1 (en) | 2013-06-06 |
| MX2014006520A (es) | 2014-11-21 |
| CN103890177A (zh) | 2014-06-25 |
| SG11201401579UA (en) | 2014-07-30 |
| ZA201403557B (en) | 2020-10-28 |
| KR102013801B1 (ko) | 2019-08-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed |