IL232107B - Methods for stimulating the growth of stem cells or progenitor cells, for inducing the return of cells to a lower degree of maturity and for creating stem cell populations - Google Patents
Methods for stimulating the growth of stem cells or progenitor cells, for inducing the return of cells to a lower degree of maturity and for creating stem cell populationsInfo
- Publication number
- IL232107B IL232107B IL232107A IL23210714A IL232107B IL 232107 B IL232107 B IL 232107B IL 232107 A IL232107 A IL 232107A IL 23210714 A IL23210714 A IL 23210714A IL 232107 B IL232107 B IL 232107B
- Authority
- IL
- Israel
- Prior art keywords
- cells
- stem
- revert
- populations
- inducing
- Prior art date
Links
- 210000000130 stem cell Anatomy 0.000 title 3
- 210000004027 cell Anatomy 0.000 title 1
- 230000001939 inductive effect Effects 0.000 title 1
- 230000004936 stimulating effect Effects 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0037—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0056—Xeno-free medium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases [EC 2.]
- C12N2501/727—Kinases (EC 2.7.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/90—Polysaccharides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161548199P | 2011-10-17 | 2011-10-17 | |
| US201261618578P | 2012-03-30 | 2012-03-30 | |
| US201261622422P | 2012-04-10 | 2012-04-10 | |
| PCT/US2012/036975 WO2012154759A2 (en) | 2011-05-09 | 2012-05-08 | Genetically engineered growth factor variants |
| US201261671588P | 2012-07-13 | 2012-07-13 | |
| US201261671558P | 2012-07-13 | 2012-07-13 | |
| US201261673617P | 2012-07-19 | 2012-07-19 | |
| US201261675264P | 2012-07-24 | 2012-07-24 | |
| US201261675292P | 2012-07-24 | 2012-07-24 | |
| US201261677442P | 2012-07-30 | 2012-07-30 | |
| US201261679021P | 2012-08-02 | 2012-08-02 | |
| US201261683155P | 2012-08-14 | 2012-08-14 | |
| US201261684654P | 2012-08-17 | 2012-08-17 | |
| US201261693712P | 2012-08-27 | 2012-08-27 | |
| PCT/US2012/060684 WO2013059373A2 (en) | 2011-10-17 | 2012-10-17 | Media for stem cell proliferation and induction |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL232107A0 IL232107A0 (en) | 2014-05-28 |
| IL232107B true IL232107B (en) | 2020-01-30 |
Family
ID=48141618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL232107A IL232107B (en) | 2011-10-17 | 2014-04-13 | Methods for stimulating the growth of stem cells or progenitor cells, for inducing the return of cells to a lower degree of maturity and for creating stem cell populations |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11591565B2 (https=) |
| EP (1) | EP2768945B1 (https=) |
| JP (5) | JP6466170B2 (https=) |
| CN (2) | CN103998598A (https=) |
| AU (1) | AU2012326137B2 (https=) |
| CA (1) | CA2852244C (https=) |
| IL (1) | IL232107B (https=) |
| WO (1) | WO2013059373A2 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2686418A4 (en) | 2011-03-17 | 2015-04-22 | Minerva Biotechnologies Corp | METHOD FOR THE PRODUCTION OF PLURIPOTENTAL STEM CELLS |
| EP2768945B1 (en) | 2011-10-17 | 2022-01-05 | Minerva Biotechnologies Corporation | Media for stem cell proliferation and induction |
| JP6748430B2 (ja) * | 2012-07-13 | 2020-09-02 | ミネルバ バイオテクノロジーズ コーポレーション | より未分化状態への細胞の誘導方法 |
| TWI659210B (zh) * | 2013-08-12 | 2019-05-11 | Minerva Biotechnologies Corporation | 加強腫瘤生長的方法 |
| CN106414726A (zh) * | 2014-04-07 | 2017-02-15 | 米纳瓦生物技术公司 | 抗nme抗体 |
| CA2976089C (en) | 2015-02-10 | 2026-01-13 | Minerva Biotechnologies Corporation | Humanized anti-muc1* antibodies |
| AU2016287603A1 (en) * | 2015-07-01 | 2018-01-25 | Minerva Biotechnologies Corporation | Method of stem cell-based organ and tissue generation |
| JP2019515643A (ja) * | 2015-09-23 | 2019-06-13 | ミネルバ バイオテクノロジーズ コーポレーション | 幹細胞分化剤のスクリーニング方法 |
| US20190194621A1 (en) * | 2016-09-08 | 2019-06-27 | Kyowa Hakko Bio Co., Ltd. | Medium for culturing stem cells, method for culturing stem cells, growth promoter for stem cells, and cell composition and method for producing same |
| JP2020500031A (ja) * | 2016-10-11 | 2020-01-09 | ミネルバ バイオテクノロジーズ コーポレーション | ヒト化抗ｍｕｃ１＊抗体及び開裂酵素の使用 |
| KR102121042B1 (ko) * | 2017-12-06 | 2020-06-09 | 이정복 | 조류의 에그로부터 분리한 세포인 배반엽 전분화능세포, 신경줄기세포, 배아섬유아세포 컨디션드 배지를 유효성분으로 하는 세포 증식, 피부재생 및 주름 개선용 배지 조성물 |
| EP3920693A4 (en) | 2019-02-04 | 2022-10-05 | Minerva Biotechnologies Corporation | ANTI-NME ANTIBODIES AND METHODS OF TREATMENT OF CANCER OR CANCER METASTASIS |
| JP2022548776A (ja) * | 2019-09-19 | 2022-11-21 | ノースウェスタン ユニバーシティ | ヒト人工多能性幹細胞のための費用効果の高い培地およびプロトコル |
| CN116367857A (zh) | 2020-06-08 | 2023-06-30 | 米纳瓦生物技术公司 | 抗nme抗体及治疗癌症或癌症转移的方法 |
| KR20230028796A (ko) | 2020-06-26 | 2023-03-02 | 미네르바 바이오테크놀로지 코포레이션 | 항-nme 항체 및 암 또는 암 전이의 치료 방법 |
| JP7581015B2 (ja) | 2020-10-30 | 2024-11-12 | 株式会社小松製作所 | データ送信システム、作業機械、および作業機械のデータ送信方法 |
| KR20250009592A (ko) | 2022-04-12 | 2025-01-17 | 미네르바 바이오테크놀로지 코포레이션 | 항-가변 muc1* 항체 및 그의 용도 |
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| EP2768945B1 (en) | 2011-10-17 | 2022-01-05 | Minerva Biotechnologies Corporation | Media for stem cell proliferation and induction |
| JP6748430B2 (ja) | 2012-07-13 | 2020-09-02 | ミネルバ バイオテクノロジーズ コーポレーション | より未分化状態への細胞の誘導方法 |
| CN111849874A (zh) | 2012-07-24 | 2020-10-30 | 米纳瓦生物技术公司 | Nme变体物种表达和抑制 |
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2012
- 2012-10-17 EP EP12841648.4A patent/EP2768945B1/en active Active
- 2012-10-17 AU AU2012326137A patent/AU2012326137B2/en active Active
- 2012-10-17 WO PCT/US2012/060684 patent/WO2013059373A2/en not_active Ceased
- 2012-10-17 JP JP2014537191A patent/JP6466170B2/ja not_active Expired - Fee Related
- 2012-10-17 CN CN201280062509.8A patent/CN103998598A/zh active Pending
- 2012-10-17 CN CN201811288611.5A patent/CN109456932A/zh active Pending
- 2012-10-17 CA CA2852244A patent/CA2852244C/en active Active
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2014
- 2014-04-13 IL IL232107A patent/IL232107B/en active IP Right Grant
- 2014-04-16 US US14/254,749 patent/US11591565B2/en active Active
-
2016
- 2016-11-29 JP JP2016231442A patent/JP2017074054A/ja active Pending
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2020
- 2020-07-17 JP JP2020122592A patent/JP2020182483A/ja active Pending
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2021
- 2021-12-24 JP JP2021211485A patent/JP2022046658A/ja active Pending
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2023
- 2023-01-12 US US18/153,974 patent/US11976295B2/en active Active
- 2023-12-21 JP JP2023216113A patent/JP2024038024A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL232107A0 (en) | 2014-05-28 |
| JP2024038024A (ja) | 2024-03-19 |
| EP2768945B1 (en) | 2022-01-05 |
| WO2013059373A3 (en) | 2013-06-20 |
| EP2768945A2 (en) | 2014-08-27 |
| JP2020182483A (ja) | 2020-11-12 |
| CA2852244A1 (en) | 2013-04-25 |
| US20150017726A1 (en) | 2015-01-15 |
| US11976295B2 (en) | 2024-05-07 |
| CN103998598A (zh) | 2014-08-20 |
| AU2012326137B2 (en) | 2018-11-29 |
| US11591565B2 (en) | 2023-02-28 |
| WO2013059373A2 (en) | 2013-04-25 |
| US20230287338A1 (en) | 2023-09-14 |
| JP2017074054A (ja) | 2017-04-20 |
| JP2022046658A (ja) | 2022-03-23 |
| CN109456932A (zh) | 2019-03-12 |
| AU2012326137A1 (en) | 2014-05-01 |
| JP2014530025A (ja) | 2014-11-17 |
| EP2768945A4 (en) | 2015-07-29 |
| CA2852244C (en) | 2023-10-17 |
| JP6466170B2 (ja) | 2019-02-06 |
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