CN103998598A - 用于干细胞增殖和诱导的培养基 - Google Patents

用于干细胞增殖和诱导的培养基 Download PDF

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Publication number
CN103998598A
CN103998598A CN201280062509.8A CN201280062509A CN103998598A CN 103998598 A CN103998598 A CN 103998598A CN 201280062509 A CN201280062509 A CN 201280062509A CN 103998598 A CN103998598 A CN 103998598A
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cells
nme7
culture medium
stem cells
nme1
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Chinese (zh)
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辛西娅·巴姆达德
贝努瓦·J·斯马格
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Minerva Biotechnologies Corp
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Minerva Biotechnologies Corp
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Priority claimed from PCT/US2012/036975 external-priority patent/WO2012154759A2/en
Application filed by Minerva Biotechnologies Corp filed Critical Minerva Biotechnologies Corp
Priority to CN201811288611.5A priority Critical patent/CN109456932A/zh
Publication of CN103998598A publication Critical patent/CN103998598A/zh
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0037—Serum-free medium, which may still contain naturally-sourced components
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0056—Xeno-free medium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/15—Transforming growth factor beta (TGF-β)
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases [EC 2.]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/90—Polysaccharides

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  • Health & Medical Sciences (AREA)
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  • Developmental Biology & Embryology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
CN201280062509.8A 2011-10-17 2012-10-17 用于干细胞增殖和诱导的培养基 Pending CN103998598A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811288611.5A CN109456932A (zh) 2011-10-17 2012-10-17 用于干细胞增殖和诱导的培养基

Applications Claiming Priority (29)

Application Number Priority Date Filing Date Title
US201161548199P 2011-10-17 2011-10-17
US61/548,199 2011-10-17
US201261618578P 2012-03-30 2012-03-30
US61/618,578 2012-03-30
US201261622422P 2012-04-10 2012-04-10
US61/622,422 2012-04-10
PCT/US2012/036975 WO2012154759A2 (en) 2011-05-09 2012-05-08 Genetically engineered growth factor variants
USPCT/US12/36975 2012-05-08
US201261671588P 2012-07-13 2012-07-13
US201261671558P 2012-07-13 2012-07-13
US61/671,558 2012-07-13
US61/671,588 2012-07-13
US201261673617P 2012-07-19 2012-07-19
US61/673,617 2012-07-19
US201261675264P 2012-07-24 2012-07-24
US201261675292P 2012-07-24 2012-07-24
US61/675,264 2012-07-24
US61/675,292 2012-07-24
US201261677442P 2012-07-30 2012-07-30
US61/677,442 2012-07-30
US201261679021P 2012-08-02 2012-08-02
US61/679,021 2012-08-02
US201261683155P 2012-08-14 2012-08-14
US61/683,155 2012-08-14
US201261684654P 2012-08-17 2012-08-17
US61/684,654 2012-08-17
US201261693712P 2012-08-27 2012-08-27
US61/693,712 2012-08-27
PCT/US2012/060684 WO2013059373A2 (en) 2011-10-17 2012-10-17 Media for stem cell proliferation and induction

Related Child Applications (1)

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CN201811288611.5A Division CN109456932A (zh) 2011-10-17 2012-10-17 用于干细胞增殖和诱导的培养基

Publications (1)

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CN103998598A true CN103998598A (zh) 2014-08-20

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CN201811288611.5A Pending CN109456932A (zh) 2011-10-17 2012-10-17 用于干细胞增殖和诱导的培养基

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US (2) US11591565B2 (https=)
EP (1) EP2768945B1 (https=)
JP (5) JP6466170B2 (https=)
CN (2) CN103998598A (https=)
AU (1) AU2012326137B2 (https=)
CA (1) CA2852244C (https=)
IL (1) IL232107B (https=)
WO (1) WO2013059373A2 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107920501A (zh) * 2015-07-01 2018-04-17 米纳瓦生物技术公司 基于干细胞的器官和组织的产生的方法
CN111511901A (zh) * 2017-12-06 2020-08-07 李廷福 包含作为从鸟类的蛋分离的细胞的胚盘多能干细胞、神经干细胞、胚胎成纤维细胞条件培养基作为有效成分的用于细胞增殖、皮肤再生及皱纹改善的培养基组合物

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EP2686418A4 (en) 2011-03-17 2015-04-22 Minerva Biotechnologies Corp METHOD FOR THE PRODUCTION OF PLURIPOTENTAL STEM CELLS
EP2768945B1 (en) 2011-10-17 2022-01-05 Minerva Biotechnologies Corporation Media for stem cell proliferation and induction
JP6748430B2 (ja) * 2012-07-13 2020-09-02 ミネルバ バイオテクノロジーズ コーポレーション より未分化状態への細胞の誘導方法
TWI659210B (zh) * 2013-08-12 2019-05-11 Minerva Biotechnologies Corporation 加強腫瘤生長的方法
CN106414726A (zh) * 2014-04-07 2017-02-15 米纳瓦生物技术公司 抗nme抗体
CA2976089C (en) 2015-02-10 2026-01-13 Minerva Biotechnologies Corporation Humanized anti-muc1* antibodies
JP2019515643A (ja) * 2015-09-23 2019-06-13 ミネルバ バイオテクノロジーズ コーポレーション 幹細胞分化剤のスクリーニング方法
US20190194621A1 (en) * 2016-09-08 2019-06-27 Kyowa Hakko Bio Co., Ltd. Medium for culturing stem cells, method for culturing stem cells, growth promoter for stem cells, and cell composition and method for producing same
JP2020500031A (ja) * 2016-10-11 2020-01-09 ミネルバ バイオテクノロジーズ コーポレーション ヒト化抗ｍｕｃ１＊抗体及び開裂酵素の使用
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JP2022548776A (ja) * 2019-09-19 2022-11-21 ノースウェスタン ユニバーシティ ヒト人工多能性幹細胞のための費用効果の高い培地およびプロトコル
CN116367857A (zh) 2020-06-08 2023-06-30 米纳瓦生物技术公司 抗nme抗体及治疗癌症或癌症转移的方法
KR20230028796A (ko) 2020-06-26 2023-03-02 미네르바 바이오테크놀로지 코포레이션 항-nme 항체 및 암 또는 암 전이의 치료 방법
JP7581015B2 (ja) 2020-10-30 2024-11-12 株式会社小松製作所 データ送信システム、作業機械、および作業機械のデータ送信方法
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Publication number Priority date Publication date Assignee Title
CN107920501A (zh) * 2015-07-01 2018-04-17 米纳瓦生物技术公司 基于干细胞的器官和组织的产生的方法
CN111511901A (zh) * 2017-12-06 2020-08-07 李廷福 包含作为从鸟类的蛋分离的细胞的胚盘多能干细胞、神经干细胞、胚胎成纤维细胞条件培养基作为有效成分的用于细胞增殖、皮肤再生及皱纹改善的培养基组合物

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