IL231668A0 - A method for in vitro expansion of hematopoietic stem cells and progenitor cells - Google Patents
A method for in vitro expansion of hematopoietic stem cells and progenitor cellsInfo
- Publication number
- IL231668A0 IL231668A0 IL231668A IL23166814A IL231668A0 IL 231668 A0 IL231668 A0 IL 231668A0 IL 231668 A IL231668 A IL 231668A IL 23166814 A IL23166814 A IL 23166814A IL 231668 A0 IL231668 A0 IL 231668A0
- Authority
- IL
- Israel
- Prior art keywords
- progenitor cells
- hematopoietic stem
- vivo expansion
- vivo
- expansion
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/145—Thrombopoietin [TPO]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2306—Interleukin-6 (IL-6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/26—Flt-3 ligand (CD135L, flk-2 ligand)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/59—Lectins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/998—Proteins not provided for elsewhere
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Developmental Biology & Embryology (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2011903899A AU2011903899A0 (en) | 2011-09-22 | Cell culture & expansion | |
| PCT/AU2012/001135 WO2013040644A1 (en) | 2011-09-22 | 2012-09-21 | Method for the ex vivo expansion of hematopoietic stem and progenitor cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL231668A0 true IL231668A0 (en) | 2014-05-28 |
Family
ID=47913674
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL231668A IL231668A0 (en) | 2011-09-22 | 2014-03-23 | A method for in vitro expansion of hematopoietic stem cells and progenitor cells |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9518250B2 (enExample) |
| EP (1) | EP2748309A4 (enExample) |
| JP (1) | JP6112462B2 (enExample) |
| KR (1) | KR20140063861A (enExample) |
| CN (1) | CN104114694A (enExample) |
| AU (1) | AU2012313347A1 (enExample) |
| CA (1) | CA2885665A1 (enExample) |
| IL (1) | IL231668A0 (enExample) |
| SG (1) | SG11201400851PA (enExample) |
| WO (1) | WO2013040644A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016178914A1 (en) * | 2015-05-01 | 2016-11-10 | Cesca Therapeutics, Inc. | Intramuscular adaminstration of autologous bone marrw for treatment |
| EP3313420B1 (en) | 2015-06-25 | 2024-03-13 | The Children's Medical Center Corporation | Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance |
| EP3331993A1 (en) * | 2015-08-05 | 2018-06-13 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Use of dermatopontin for maintaining hematopoietic stem and/or progenitor cells in culture |
| US20200392533A1 (en) * | 2017-04-11 | 2020-12-17 | President And Fellows Of Harvard College | In vivo gene editing of blood progenitors |
| CN110093313B (zh) * | 2018-01-29 | 2023-04-14 | 华南生物医药研究院 | 促进造血干/祖细胞分化为红系细胞的诱导培养基及应用 |
| EP3836974A4 (en) | 2018-08-18 | 2022-06-15 | President and Fellows of Harvard College | IN SITU GENE EDIT |
| US20230212516A1 (en) * | 2020-06-02 | 2023-07-06 | Cornell University | Methods for expanding hematopoietic stem cells |
| CN115861151B (zh) * | 2021-09-23 | 2025-10-17 | 鸿海精密工业股份有限公司 | 细胞采收提醒方法及系统 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020132017A1 (en) * | 1996-12-09 | 2002-09-19 | Moore Jeffrey G. | Composition and method for preserving progenitor cells |
| US20050137126A1 (en) * | 2003-04-09 | 2005-06-23 | Natlmmune A/S | Treatment of SARS in individuals |
| IL161903A0 (en) * | 2003-07-17 | 2005-11-20 | Gamida Cell Ltd | Ex vivo progenitor and stem cell expansion for usein the treatment of disease of endodermally- deri ved organs |
| US20060205071A1 (en) | 2003-07-17 | 2006-09-14 | Gamida-Cell Ltd. | Methods for ex-vivo expanding stem/progenitor cells |
| CN1297659C (zh) * | 2004-02-11 | 2007-01-31 | 上海伯瑞生物技术发展有限公司 | 一种造血细胞灌注培养方法和装置 |
| US7767453B2 (en) * | 2004-10-20 | 2010-08-03 | Whitehead Institute For Biomedical Research | Cultured hematopoietic stem cells and method for expansion and analysis thereof |
| KR20090009186A (ko) * | 2005-12-06 | 2009-01-22 | 디파트먼트 오브 바이오테크놀러지 | 사람의 조혈 줄기 세포 또는 선조 세포의 보존 방법 |
| JP2008237136A (ja) | 2007-03-28 | 2008-10-09 | Foundation For Biomedical Research & Innovation | ヒト造血細胞の培養方法 |
| WO2008149129A1 (en) | 2007-06-08 | 2008-12-11 | Nova Thera Limited | Cell expansion |
| CN101508975A (zh) * | 2009-03-26 | 2009-08-19 | 大连理工大学 | 一种低氧条件下微囊化成骨细胞支持和调控造血干/祖细胞体外扩增的方法 |
| WO2010142295A1 (en) * | 2009-06-10 | 2010-12-16 | Rigshospitalet | Ficolin-3 assay |
| US20120169643A1 (en) | 2009-09-09 | 2012-07-05 | Sharp Kabushiki Kaisha | Gesture determination device and method of same |
| CN102597223B (zh) * | 2009-09-11 | 2017-05-10 | 宝生物工程株式会社 | 生产天然杀伤细胞的方法 |
-
2012
- 2012-09-21 EP EP12832834.1A patent/EP2748309A4/en not_active Withdrawn
- 2012-09-21 AU AU2012313347A patent/AU2012313347A1/en not_active Abandoned
- 2012-09-21 CA CA2885665A patent/CA2885665A1/en active Pending
- 2012-09-21 CN CN201280052478.8A patent/CN104114694A/zh active Pending
- 2012-09-21 WO PCT/AU2012/001135 patent/WO2013040644A1/en not_active Ceased
- 2012-09-21 JP JP2014531047A patent/JP6112462B2/ja not_active Expired - Fee Related
- 2012-09-21 KR KR1020147010617A patent/KR20140063861A/ko not_active Withdrawn
- 2012-09-21 US US14/346,160 patent/US9518250B2/en not_active Expired - Fee Related
- 2012-09-21 SG SG11201400851PA patent/SG11201400851PA/en unknown
-
2014
- 2014-03-23 IL IL231668A patent/IL231668A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2012313347A1 (en) | 2014-05-08 |
| JP2014527820A (ja) | 2014-10-23 |
| US9518250B2 (en) | 2016-12-13 |
| CA2885665A1 (en) | 2013-03-28 |
| SG11201400851PA (en) | 2014-04-28 |
| EP2748309A4 (en) | 2015-03-11 |
| CN104114694A (zh) | 2014-10-22 |
| EP2748309A1 (en) | 2014-07-02 |
| JP6112462B2 (ja) | 2017-04-12 |
| KR20140063861A (ko) | 2014-05-27 |
| US20140286915A1 (en) | 2014-09-25 |
| WO2013040644A1 (en) | 2013-03-28 |
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