IL231100B - Threonine synthase from Nicotiana tobacco and methods and uses thereof - Google Patents

Threonine synthase from Nicotiana tobacco and methods and uses thereof

Info

Publication number
IL231100B
IL231100B IL231100A IL23110014A IL231100B IL 231100 B IL231100 B IL 231100B IL 231100 A IL231100 A IL 231100A IL 23110014 A IL23110014 A IL 23110014A IL 231100 B IL231100 B IL 231100B
Authority
IL
Israel
Prior art keywords
methods
nicotiana tabacum
threonine synthase
synthase
threonine
Prior art date
Application number
IL231100A
Other languages
English (en)
Hebrew (he)
Other versions
IL231100A0 (en
Original Assignee
Philip Morris Products Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philip Morris Products Sa filed Critical Philip Morris Products Sa
Publication of IL231100A0 publication Critical patent/IL231100A0/en
Publication of IL231100B publication Critical patent/IL231100B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H5/00Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B13/00Tobacco for pipes, for cigars, e.g. cigar inserts, or for cigarettes; Chewing tobacco; Snuff
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C381/00Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8251Amino acid content, e.g. synthetic storage proteins, altering amino acid biosynthesis
    • C12N15/8253Methionine or cysteine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6895Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/13Plant traits
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/03Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03001Threonine synthase (4.2.3.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Nutrition Science (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Physiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Environmental Sciences (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Manufacture Of Tobacco Products (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL231100A 2011-09-02 2014-02-24 Threonine synthase from Nicotiana tobacco and methods and uses thereof IL231100B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20110179889 EP2565271A1 (de) 2011-09-02 2011-09-02 Threonin-Synthase aus Nicotiana Tabacum und Verfahren und Verwendungen davon
PCT/EP2012/003663 WO2013029800A1 (en) 2011-09-02 2012-08-31 Threonine synthase from nicotiana tabacum and methods and uses thereof

Publications (2)

Publication Number Publication Date
IL231100A0 IL231100A0 (en) 2014-04-30
IL231100B true IL231100B (en) 2018-06-28

Family

ID=46832335

Family Applications (1)

Application Number Title Priority Date Filing Date
IL231100A IL231100B (en) 2011-09-02 2014-02-24 Threonine synthase from Nicotiana tobacco and methods and uses thereof

Country Status (16)

Country Link
US (1) US10501732B2 (de)
EP (3) EP2565271A1 (de)
JP (1) JP6225108B2 (de)
KR (1) KR102012531B1 (de)
CN (1) CN103946384A (de)
AU (1) AU2012301350B2 (de)
BR (1) BR112014004641B1 (de)
ES (1) ES2685797T3 (de)
IL (1) IL231100B (de)
MX (1) MX362700B (de)
MY (1) MY172266A (de)
PL (1) PL2751273T3 (de)
RU (1) RU2689719C2 (de)
SG (1) SG11201400216VA (de)
UA (1) UA116438C2 (de)
WO (1) WO2013029800A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2565271A1 (de) 2011-09-02 2013-03-06 Philip Morris Products S.A. Threonin-Synthase aus Nicotiana Tabacum und Verfahren und Verwendungen davon
WO2015169925A1 (en) * 2014-05-08 2015-11-12 Philip Morris Products S.A. Plant promoter
CN108292328B (zh) * 2015-11-10 2022-04-19 美国陶氏益农公司 用于预测转基因沉默风险的方法和系统
WO2018038092A1 (ja) * 2016-08-22 2018-03-01 日本たばこ産業株式会社 乾燥たばこ材料の生産方法
UY37482A (es) * 2016-11-16 2018-05-31 Cellectis Métodos para alterar el contenido de aminoácidos en plantas mediante mutaciones de desplazamiento de marco
BR112020017430A2 (pt) 2018-03-28 2021-01-19 Philip Morris Products S.A. Modulação do teor de açúcar redutor em uma planta
WO2019185703A1 (en) 2018-03-28 2019-10-03 Philip Morris Products S.A. Modulating amino acid content in a plant
CN109182347B (zh) * 2018-09-11 2020-07-24 中国农业科学院烟草研究所 烟草NtTS3基因在控制烟草叶片衰老中的应用
MX2021007628A (es) 2018-12-30 2021-08-11 Philip Morris Products Sa Modulacion de niveles de nitrato en plantas a traves de la mutacion de la nitrato reductasa.
WO2021063860A1 (en) 2019-10-01 2021-04-08 Philip Morris Products S.A. Modulating reducing sugar content in a plant (inv)
JP2022552638A (ja) 2019-10-01 2022-12-19 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 植物における糖およびアミノ酸含有量の調節(sultr3)
WO2023036691A1 (en) 2021-09-10 2023-03-16 Philip Morris Products S.A. Modulating alkaloid profiles in nicotiana tabacum
WO2023117661A1 (en) 2021-12-20 2023-06-29 Philip Morris Products S.A. Increasing anatabine in tobacco leaf by regulating methyl putrescine oxidase
WO2023117701A1 (en) 2021-12-21 2023-06-29 Philip Morris Products S.A. Modulation of nicotine production by alteration of nicotinamidase expression or function in plants
CN114720645B (zh) * 2022-05-18 2022-08-26 汉王科技股份有限公司 嗅觉受体在识别3-甲硫基丙醛中的用途和检测3-甲硫基丙醛的方法
WO2024079137A1 (en) 2022-10-13 2024-04-18 Philip Morris Products S.A. Increasing leaf biomass and nitrogen use efficiency by regulating ntp2
WO2024160864A1 (en) 2023-02-02 2024-08-08 Philip Morris Products S.A. Modulation of sugar transporters
WO2024160860A1 (en) 2023-02-02 2024-08-08 Philip Morris Products S.A. Modulation of genes coding for lysine ketoglutarate reductase

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ID24686A (id) 1997-06-06 2000-07-27 Du Pont Enzim-enzim biosintetik asam amino tanaman
AU3763100A (en) * 1999-03-18 2000-10-04 Rutgers, The State University Transgenic plants having imroved flavor properties
US20020013389A1 (en) * 2000-02-02 2002-01-31 Taylor Donald W. Polymeric blends and composites and laminates thereof
WO2001075130A1 (en) * 2000-04-04 2001-10-11 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Transgenic plants with an increased methionine content
WO2002088301A2 (en) * 2001-05-02 2002-11-07 Gavish Galilee Bio Applications Ltd. Increased methionine in transgenic plants expressing mutant cystathionine gamma-synthase
US7700834B2 (en) * 2001-11-13 2010-04-20 U.S. Smokless Tobacco Company Nicotiana nucleic acid molecules and uses thereof
US20070199097A1 (en) * 2004-09-03 2007-08-23 U.S. Smokeless Tobacco Company Tobacco plants having a mutation in a nicotine demethylase gene
EP1851317B1 (de) 2005-02-23 2011-10-26 North Carolina State University Veränderung des alkaloidgehaltes in tabak durch modifikation spezifischer cytochrome p450 gene.
BRPI0717355B1 (pt) 2006-10-13 2018-01-16 North Carolina State University Método para obtenção de uma planta transgênica de nicotina, método para obtenção de uma semente; construto de ácido nucléico recombinante; método de redução da conversão de nicotina em nornicotina em uma planta de nicotina
RU2324737C1 (ru) * 2006-10-18 2008-05-20 Институт цитологии и генетики Сибирского отделения Российской академии наук (СО РАН) Способ получения трансгенных растений табака с повышенным содержанием пролина
BRPI0820042B1 (pt) 2007-11-12 2020-05-19 North Carolina State University método de obtenção de uma planta de tabaco, ou célula ou parte desta, tendo níveis reduzidos de nornicotina, produto de tabaco, método para fabricar um produto de tabaco, polinucleotídeo isolado, cassete de expressão, polipetpídeo isolado e método de obtenção de uma planta, ou parte de planta desta, do gênero nicotiana
PL2231861T3 (pl) 2007-12-13 2015-04-30 Philip Morris Products Sa Rośliny transgeniczne modyfikowane w celu zmniejszenia transportu kadmu, produkty pochodne i metody związane
US7883371B1 (en) 2009-07-22 2011-02-08 Hon Hai Precision Ind. Co., Ltd. Electrical connector with improved contact footprints
EP2565271A1 (de) 2011-09-02 2013-03-06 Philip Morris Products S.A. Threonin-Synthase aus Nicotiana Tabacum und Verfahren und Verwendungen davon

Also Published As

Publication number Publication date
AU2012301350A1 (en) 2014-03-20
BR112014004641B1 (pt) 2022-08-09
IL231100A0 (en) 2014-04-30
EP2565271A1 (de) 2013-03-06
JP6225108B2 (ja) 2017-11-01
SG11201400216VA (en) 2014-03-28
JP2014533926A (ja) 2014-12-18
UA116438C2 (uk) 2018-03-26
ES2685797T3 (es) 2018-10-11
US20150106971A1 (en) 2015-04-16
US10501732B2 (en) 2019-12-10
RU2014112759A (ru) 2015-10-10
KR102012531B1 (ko) 2019-08-20
EP2751273B1 (de) 2018-07-04
KR20140057642A (ko) 2014-05-13
AU2012301350B2 (en) 2016-04-14
BR112014004641A2 (pt) 2020-10-27
RU2689719C2 (ru) 2019-05-28
EP2751273A1 (de) 2014-07-09
PL2751273T3 (pl) 2019-05-31
MY172266A (en) 2019-11-20
WO2013029800A1 (en) 2013-03-07
CN103946384A (zh) 2014-07-23
MX2014002498A (es) 2014-11-14
MX362700B (es) 2019-02-01
EP3395948A1 (de) 2018-10-31

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