IL22192A - Manufacture of benzodiazepine derivatives - Google Patents

Manufacture of benzodiazepine derivatives

Info

Publication number
IL22192A
IL22192A IL22192A IL2219264A IL22192A IL 22192 A IL22192 A IL 22192A IL 22192 A IL22192 A IL 22192A IL 2219264 A IL2219264 A IL 2219264A IL 22192 A IL22192 A IL 22192A
Authority
IL
Israel
Prior art keywords
chemical equivalent
alkylate
whenever prepared
obvious chemical
formula
Prior art date
Application number
IL22192A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL22192A publication Critical patent/IL22192A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/20—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL22192A 1963-10-29 1964-10-05 Manufacture of benzodiazepine derivatives IL22192A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US319673A US3312688A (en) 1963-10-29 1963-10-29 Process for preparing 2-aminobenzodiazepines

Publications (1)

Publication Number Publication Date
IL22192A true IL22192A (en) 1968-01-25

Family

ID=23243220

Family Applications (1)

Application Number Title Priority Date Filing Date
IL22192A IL22192A (en) 1963-10-29 1964-10-05 Manufacture of benzodiazepine derivatives

Country Status (14)

Country Link
US (1) US3312688A (fr)
BE (1) BE654924A (fr)
BR (1) BR6463736D0 (fr)
CH (1) CH443319A (fr)
DE (2) DE1445910A1 (fr)
DK (1) DK114271B (fr)
ES (1) ES305413A1 (fr)
FR (1) FR1442311A (fr)
GB (1) GB1058739A (fr)
IL (1) IL22192A (fr)
NL (3) NL139527B (fr)
NO (1) NO118910B (fr)
OA (1) OA00943A (fr)
SE (2) SE329625B (fr)

Also Published As

Publication number Publication date
DE1445910A1 (de) 1969-01-23
FR1442311A (fr) 1966-06-17
BR6463736D0 (pt) 1973-07-17
SE355580B (fr) 1973-04-30
NL139527B (nl) 1973-08-15
NO118910B (fr) 1970-03-02
DK114271B (da) 1969-06-16
OA00943A (fr) 1968-03-22
CH443319A (de) 1967-09-15
NL7115680A (fr) 1972-02-25
SE329625B (fr) 1970-10-19
NL6412484A (fr) 1965-05-03
BE654924A (fr) 1965-04-28
GB1058739A (en) 1967-02-15
DE1695217A1 (de) 1972-02-17
US3312688A (en) 1967-04-04
NL7115681A (fr) 1972-02-25
ES305413A1 (es) 1965-05-01

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