DK114271B - Fremgangsmåde til fremstilling af 5-aryl-1,4-benzodiazepin-4-oxider. - Google Patents

Fremgangsmåde til fremstilling af 5-aryl-1,4-benzodiazepin-4-oxider.

Info

Publication number
DK114271B
DK114271B DK516164AA DK516164A DK114271B DK 114271 B DK114271 B DK 114271B DK 516164A A DK516164A A DK 516164AA DK 516164 A DK516164 A DK 516164A DK 114271 B DK114271 B DK 114271B
Authority
DK
Denmark
Prior art keywords
benzodiazepine
oxides
aryl
preparation
Prior art date
Application number
DK516164AA
Other languages
English (en)
Inventor
G Archer
L Sternbach
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK114271B publication Critical patent/DK114271B/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/20Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK516164AA 1963-10-29 1964-10-19 Fremgangsmåde til fremstilling af 5-aryl-1,4-benzodiazepin-4-oxider. DK114271B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US319673A US3312688A (en) 1963-10-29 1963-10-29 Process for preparing 2-aminobenzodiazepines

Publications (1)

Publication Number Publication Date
DK114271B true DK114271B (da) 1969-06-16

Family

ID=23243220

Family Applications (1)

Application Number Title Priority Date Filing Date
DK516164AA DK114271B (da) 1963-10-29 1964-10-19 Fremgangsmåde til fremstilling af 5-aryl-1,4-benzodiazepin-4-oxider.

Country Status (14)

Country Link
US (1) US3312688A (da)
BE (1) BE654924A (da)
BR (1) BR6463736D0 (da)
CH (1) CH443319A (da)
DE (2) DE1445910A1 (da)
DK (1) DK114271B (da)
ES (1) ES305413A1 (da)
FR (1) FR1442311A (da)
GB (1) GB1058739A (da)
IL (1) IL22192A (da)
NL (3) NL139527B (da)
NO (1) NO118910B (da)
OA (1) OA00943A (da)
SE (2) SE355580B (da)

Also Published As

Publication number Publication date
DE1445910A1 (de) 1969-01-23
CH443319A (de) 1967-09-15
IL22192A (en) 1968-01-25
FR1442311A (fr) 1966-06-17
NL139527B (nl) 1973-08-15
NL7115680A (da) 1972-02-25
SE329625B (da) 1970-10-19
OA00943A (fr) 1968-03-22
NO118910B (da) 1970-03-02
ES305413A1 (es) 1965-05-01
BR6463736D0 (pt) 1973-07-17
US3312688A (en) 1967-04-04
BE654924A (da) 1965-04-28
NL6412484A (da) 1965-05-03
GB1058739A (en) 1967-02-15
DE1695217A1 (de) 1972-02-17
NL7115681A (da) 1972-02-25
SE355580B (da) 1973-04-30

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