NL139527B - Werkwijze voor de bereiding van benzodiazepinederivaten. - Google Patents

Werkwijze voor de bereiding van benzodiazepinederivaten.

Info

Publication number
NL139527B
NL139527B NL646412484A NL6412484A NL139527B NL 139527 B NL139527 B NL 139527B NL 646412484 A NL646412484 A NL 646412484A NL 6412484 A NL6412484 A NL 6412484A NL 139527 B NL139527 B NL 139527B
Authority
NL
Netherlands
Prior art keywords
preparation
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Application number
NL646412484A
Other languages
English (en)
Other versions
NL6412484A (nl
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NL6412484A publication Critical patent/NL6412484A/xx
Publication of NL139527B publication Critical patent/NL139527B/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/20Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NL646412484A 1963-10-29 1964-10-27 Werkwijze voor de bereiding van benzodiazepinederivaten. NL139527B (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US319673A US3312688A (en) 1963-10-29 1963-10-29 Process for preparing 2-aminobenzodiazepines

Publications (2)

Publication Number Publication Date
NL6412484A NL6412484A (nl) 1965-05-03
NL139527B true NL139527B (nl) 1973-08-15

Family

ID=23243220

Family Applications (3)

Application Number Title Priority Date Filing Date
NL646412484A NL139527B (nl) 1963-10-29 1964-10-27 Werkwijze voor de bereiding van benzodiazepinederivaten.
NL7115681A NL7115681A (nl) 1963-10-29 1971-11-15
NL7115680A NL7115680A (nl) 1963-10-29 1971-11-15

Family Applications After (2)

Application Number Title Priority Date Filing Date
NL7115681A NL7115681A (nl) 1963-10-29 1971-11-15
NL7115680A NL7115680A (nl) 1963-10-29 1971-11-15

Country Status (14)

Country Link
US (1) US3312688A (nl)
BE (1) BE654924A (nl)
BR (1) BR6463736D0 (nl)
CH (1) CH443319A (nl)
DE (2) DE1695217A1 (nl)
DK (1) DK114271B (nl)
ES (1) ES305413A1 (nl)
FR (1) FR1442311A (nl)
GB (1) GB1058739A (nl)
IL (1) IL22192A (nl)
NL (3) NL139527B (nl)
NO (1) NO118910B (nl)
OA (1) OA00943A (nl)
SE (2) SE355580B (nl)

Also Published As

Publication number Publication date
BR6463736D0 (pt) 1973-07-17
BE654924A (nl) 1965-04-28
NL7115680A (nl) 1972-02-25
CH443319A (de) 1967-09-15
SE355580B (nl) 1973-04-30
OA00943A (fr) 1968-03-22
DE1695217A1 (de) 1972-02-17
FR1442311A (fr) 1966-06-17
SE329625B (nl) 1970-10-19
DE1445910A1 (de) 1969-01-23
ES305413A1 (es) 1965-05-01
NL6412484A (nl) 1965-05-03
NO118910B (nl) 1970-03-02
US3312688A (en) 1967-04-04
NL7115681A (nl) 1972-02-25
IL22192A (en) 1968-01-25
DK114271B (da) 1969-06-16
GB1058739A (en) 1967-02-15

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Legal Events

Date Code Title Description
V1 Lapsed because of non-payment of the annual fee
NL80 Abbreviated name of patent owner mentioned of already nullified patent

Owner name: HOFFMANN