NL145557B - Werkwijze voor de bereiding van nucleosiden. - Google Patents

Werkwijze voor de bereiding van nucleosiden.

Info

Publication number
NL145557B
NL145557B NL666610360A NL6610360A NL145557B NL 145557 B NL145557 B NL 145557B NL 666610360 A NL666610360 A NL 666610360A NL 6610360 A NL6610360 A NL 6610360A NL 145557 B NL145557 B NL 145557B
Authority
NL
Netherlands
Prior art keywords
nucleosides
preparation
Prior art date
Application number
NL666610360A
Other languages
English (en)
Other versions
NL6610360A (nl
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NL6610360A publication Critical patent/NL6610360A/xx
Publication of NL145557B publication Critical patent/NL145557B/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/10Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NL666610360A 1965-07-22 1966-07-22 Werkwijze voor de bereiding van nucleosiden. NL145557B (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47417565A 1965-07-22 1965-07-22
US474145A US3354160A (en) 1965-07-22 1965-07-22 Tri-lower alkyl-silyl-5-fluoropyrimidines

Publications (2)

Publication Number Publication Date
NL6610360A NL6610360A (nl) 1967-01-23
NL145557B true NL145557B (nl) 1975-04-15

Family

ID=27044368

Family Applications (1)

Application Number Title Priority Date Filing Date
NL666610360A NL145557B (nl) 1965-07-22 1966-07-22 Werkwijze voor de bereiding van nucleosiden.

Country Status (8)

Country Link
US (1) US3354160A (nl)
BE (1) BE684319A (nl)
BR (1) BR6681446D0 (nl)
CH (1) CH500203A (nl)
DE (1) DE1695151A1 (nl)
GB (1) GB1080491A (nl)
NL (1) NL145557B (nl)
SE (1) SE320077B (nl)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3479334A (en) * 1967-09-29 1969-11-18 Upjohn Co Process for selectively preparing lincomycin 7 - acylates and 7-carbonates
US3514440A (en) * 1968-01-23 1970-05-26 Upjohn Co 7-epimers of lincomycin and related compounds and processes for making the same
US3868373A (en) * 1970-01-27 1975-02-25 Hoffmann La Roche 4-Amino-5-fluoro-2-tri(lower alkyl) silyloxypyrimidines
DE2122991C2 (de) * 1971-05-04 1982-06-09 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von Cytosin- und 6-Azacytosinnucleosiden
US3919193A (en) * 1973-07-06 1975-11-11 Icn Pharmaceuticals 3-Deazaguanosine and derivatives thereof
JPS5540598B2 (nl) * 1974-05-15 1980-10-18
DE2508312A1 (de) * 1975-02-24 1976-09-02 Schering Ag Neues verfahren zur herstellung von nucleosiden
DE2514275A1 (de) * 1975-03-27 1976-10-14 Schering Ag Verfahren zur herstellung von n- (polysaccharidyl)-stickstoffheterocyclen, insbesondere von pyrimidin- oder purinbasen
DE2648239C3 (de) * 1975-10-24 1981-11-12 Rikagaku Kenkyusho, Wako, Saitama Di-(trialkylstannyl)-pyrimidinderivate, Verfahren zu ihrer Herstellung und Verfahren zu ihrer Weiterverarbeitung zu nucleosidartigen Pyrimidinderivaten
US4024143A (en) * 1976-03-11 1977-05-17 Pcr, Inc. Silylation of 5-fluoro-6-hydroxy or alkoxy pyrimidine
DE2621645C3 (de) * 1976-05-13 1981-08-06 Schering Ag Berlin Und Bergkamen, 1000 Berlin Verfahren zur Herstellung von Aminoderivaten von N-Heterocyclen
US4048432A (en) * 1976-05-17 1977-09-13 Parke, Davis & Company 9-(3,5-Di-O-acyl-β-D-arabinofuranosyl)adenine compounds and method for their production
US4055717A (en) * 1976-05-17 1977-10-25 Parke, Davis & Company 9-(3-O-Acyl-β-D-arabinofuranosyl)adenine compounds, 9-(2,3-di-O-acyl-β-D-arabinofuranosyl)-adenine compounds, and method for their production
DE2721466A1 (de) * 1977-05-12 1978-11-16 Robugen Gmbh Verfahren zur herstellung von 2'-desoxyribofuranosylnucleosiden
DE2757365A1 (de) * 1977-12-20 1979-06-21 Schering Ag Neues verfahren zur herstellung von nucleosiden
GB2060604B (en) * 1979-10-03 1983-11-23 Univ Birmingham And Stichting E15-(2-halogenovinyl)-2'-deoxycytidines
EP0227844B1 (en) * 1985-07-22 1992-05-13 Teijin Limited Antiviral drug
WO1997000882A1 (en) * 1995-06-23 1997-01-09 Oxford Glycosciences (Uk) Limited Therapeutic compounds
JP5749017B2 (ja) 2008-01-22 2015-07-15 ダウ アグロサイエンシィズ エルエルシー 5−フルオロピリミジン誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3155646A (en) * 1960-08-23 1964-11-03 Upjohn Co 1-arabinofuranosyl-5-halouracil and process for the preparation thereof
US3183226A (en) * 1961-01-10 1965-05-11 Upjohn Co Process for transforming 1-beta-d-xylofuranosyluracil nucleosides into 1-beta-d-arabinofuranosyluracil nucleosides
US3208997A (en) * 1962-11-15 1965-09-28 Sankyo Co Process for preparing purine and pyrimidine nucleosides

Also Published As

Publication number Publication date
NL6610360A (nl) 1967-01-23
BR6681446D0 (pt) 1973-12-26
US3354160A (en) 1967-11-21
DE1695151A1 (de) 1970-12-17
BE684319A (nl) 1967-01-19
GB1080491A (en) 1967-08-23
SE320077B (nl) 1970-02-02
CH500203A (de) 1970-12-15

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Legal Events

Date Code Title Description
VJC Lapsed due to non-payment of the due maintenance fee for the patent or patent application