IL218119A - Antibodies for detecting integrin complex in ffpe material - Google Patents

Antibodies for detecting integrin complex in ffpe material

Info

Publication number
IL218119A
IL218119A IL218119A IL21811912A IL218119A IL 218119 A IL218119 A IL 218119A IL 218119 A IL218119 A IL 218119A IL 21811912 A IL21811912 A IL 21811912A IL 218119 A IL218119 A IL 218119A
Authority
IL
Israel
Prior art keywords
antibodies
detection
ffpe material
integrin complexes
integrin
Prior art date
Application number
IL218119A
Other languages
English (en)
Hebrew (he)
Other versions
IL218119A0 (en
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of IL218119A0 publication Critical patent/IL218119A0/en
Publication of IL218119A publication Critical patent/IL218119A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70546Integrin superfamily, e.g. VLAs, leuCAM, GPIIb/GPIIIa, LPAM

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IL218119A 2009-08-19 2012-02-14 Antibodies for detecting integrin complex in ffpe material IL218119A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09010666 2009-08-19
PCT/EP2010/004313 WO2011020529A2 (fr) 2009-08-19 2010-07-15 Anticorps pour la détection de complexes d'intégrine dans une matière ffpe

Publications (2)

Publication Number Publication Date
IL218119A0 IL218119A0 (en) 2012-04-30
IL218119A true IL218119A (en) 2015-08-31

Family

ID=42813245

Family Applications (1)

Application Number Title Priority Date Filing Date
IL218119A IL218119A (en) 2009-08-19 2012-02-14 Antibodies for detecting integrin complex in ffpe material

Country Status (18)

Country Link
US (2) US8420348B2 (fr)
EP (1) EP2467401B1 (fr)
JP (1) JP5734978B2 (fr)
KR (1) KR101606236B1 (fr)
CN (1) CN102597001B (fr)
AU (1) AU2010285265B2 (fr)
BR (1) BR112012003686B1 (fr)
CA (1) CA2771441C (fr)
DK (1) DK2467401T3 (fr)
EA (1) EA032728B1 (fr)
ES (1) ES2622487T3 (fr)
HK (1) HK1173455A1 (fr)
IL (1) IL218119A (fr)
MX (1) MX2012001741A (fr)
PT (1) PT2467401T (fr)
SG (1) SG178348A1 (fr)
WO (1) WO2011020529A2 (fr)
ZA (1) ZA201201990B (fr)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2733492T3 (en) 2008-08-05 2016-04-25 Toray Industries Method for detection of cancer
KR101667319B1 (ko) 2008-08-05 2016-10-18 도레이 카부시키가이샤 암의 치료 및 예방용 의약 조성물
RU2603742C2 (ru) 2010-02-04 2016-11-27 Торэй Индастриз, Инк. Фармацевтическая композиция для лечения и/или профилактики рака
CA2788720C (fr) 2010-02-04 2019-08-20 Takayoshi Ido Agent pharmaceutique destine au traitement et/ou a la prevention du cancer
KR101842893B1 (ko) 2010-02-04 2018-03-28 도레이 카부시키가이샤 암의 치료 및/또는 예방용 의약 조성물
PT2672994T (pt) 2011-02-11 2018-10-22 Merck Patent Gmbh Anticorpo anti-integrina alfa-v para o tratamento do cancro da próstata
DK2740793T3 (en) 2011-08-04 2018-01-22 Toray Industries PHARMACEUTICAL COMPOSITION FOR CANCER TREATMENT AND / OR PREVENTION
PT2740489T (pt) 2011-08-04 2017-01-10 Toray Industries Composição farmacêutica para o tratamento e/ou a prevenção do cancro pancreático
PL2740795T3 (pl) 2011-08-04 2017-04-28 Toray Industries, Inc. Kompozycja lekowa do leczenia nowotworu i/lub zapobiegania nowotworowi
ES2629061T3 (es) 2011-08-04 2017-08-07 Toray Industries, Inc. Método para la detección de cáncer pancreático
DK2740794T3 (en) 2011-08-04 2018-06-14 Toray Industries PHARMACEUTICAL COMPOSITION FOR TREATMENT AND / OR CANCER PREVENTION
PT2740798T (pt) 2011-08-04 2017-03-13 Toray Industries Composição de fármaco para o tratamento e/ou a prevenção de cancro
EP2740796B1 (fr) 2011-08-04 2017-05-17 Toray Industries, Inc. Composition pharmaceutique destinée à traiter ou à prévenir le cancer
ES2643397T3 (es) * 2011-08-17 2017-11-22 The Regents Of The University Of California Anticuerpos que se unen con integrina alfa-v beta-8
PT2818481T (pt) 2012-02-21 2019-10-25 Toray Industries Composição farmacêutica para tratamento e/ou prevenção de cancro
ES2739612T3 (es) 2012-02-21 2020-02-03 Toray Industries Composición farmacéutica para el tratamiento de cáncer
CN104114583B (zh) 2012-02-21 2019-11-19 东丽株式会社 癌的治疗和/或预防用药物组合物
ES2643241T3 (es) 2012-02-21 2017-11-21 Toray Industries, Inc. Composición medicinal para tratar y/o prevenir el cáncer
AU2013241043B2 (en) 2012-03-30 2017-11-09 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prevention of gall bladder cancer
ES2656620T3 (es) 2012-03-30 2018-02-27 Toray Industries, Inc. Composición farmacéutica para el tratamiento y/o la prevención del cáncer de hígado
ES2769831T3 (es) 2012-07-19 2020-06-29 Toray Industries Método para detectar cáncer
PL2876446T3 (pl) 2012-07-19 2019-06-28 Toray Industries, Inc. Sposób wykrywania nowotworu
TWI646230B (zh) 2013-08-05 2019-01-01 扭轉生物科技有限公司 重新合成之基因庫
WO2015020212A1 (fr) * 2013-08-09 2015-02-12 東レ株式会社 Composition pharmaceutique pour le traitement et/ou la prévention du cancer
AU2015218355B2 (en) 2014-02-14 2019-09-12 Arkansas Children's Hospital Research Institute, Inc. Acetaminophen protein adducts and methods of use thereof
WO2016026956A1 (fr) * 2014-08-22 2016-02-25 Baxalta GmbH Détection de contaminations cho-mif
EP3009147A1 (fr) 2014-10-16 2016-04-20 INSERM (Institut National de la Santé et de la Recherche Médicale) Procédé de traitement de glioblastome résistant
WO2016090163A2 (fr) * 2014-12-03 2016-06-09 Board Of Trustees Of The University Of Arkansas Anticorps anti-acétaminophène et produits d'addition acétaminophène-protéine
CA2975852A1 (fr) 2015-02-04 2016-08-11 Twist Bioscience Corporation Procedes et dispositifs pour assemblage de novo d'acide oligonucleique
US9981239B2 (en) 2015-04-21 2018-05-29 Twist Bioscience Corporation Devices and methods for oligonucleic acid library synthesis
CA2998169A1 (fr) 2015-09-18 2017-03-23 Twist Bioscience Corporation Banques de variants d'acides oligonucleiques et synthese de ceux-ci
CN108698012A (zh) 2015-09-22 2018-10-23 特韦斯特生物科学公司 用于核酸合成的柔性基底
WO2017182834A1 (fr) 2016-04-19 2017-10-26 INSERM (Institut National de la Santé et de la Recherche Médicale) Nouvelle méthode de traitement d'un glioblastome résistant
US10417457B2 (en) 2016-09-21 2019-09-17 Twist Bioscience Corporation Nucleic acid based data storage
US11550939B2 (en) 2017-02-22 2023-01-10 Twist Bioscience Corporation Nucleic acid based data storage using enzymatic bioencryption
WO2018231864A1 (fr) 2017-06-12 2018-12-20 Twist Bioscience Corporation Méthodes d'assemblage d'acides nucléiques continus
EP3638782A4 (fr) 2017-06-12 2021-03-17 Twist Bioscience Corporation Méthodes d'assemblage d'acides nucléiques sans joint
CN111566125A (zh) 2017-09-11 2020-08-21 特韦斯特生物科学公司 Gpcr结合蛋白及其合成
KR20240024357A (ko) 2017-10-20 2024-02-23 트위스트 바이오사이언스 코포레이션 폴리뉴클레오타이드 합성을 위한 가열된 나노웰
US11820823B2 (en) * 2017-10-27 2023-11-21 Kite Pharma, Inc. T cell receptor antigen binding molecules and methods of use thereof
EP3814497A4 (fr) 2018-05-18 2022-03-02 Twist Bioscience Corporation Polynucléotides, réactifs, et procédés d'hybridation d'acides nucléiques
TW202024131A (zh) * 2018-09-07 2020-07-01 美商輝瑞大藥廠 抗-αvβ8抗體及組合物及其用途
CA3123046A1 (fr) * 2018-12-21 2020-06-25 Board Of Regents, The University Of Texas System Anticorps dicer phosphoryle et ses procedes d'utilisation
WO2020141608A1 (fr) * 2019-01-04 2020-07-09 国立大学法人京都大学 Méthode de test pour la rectocolite hémorragique et la cholangite sclérosante primitive
SG11202109283UA (en) 2019-02-26 2021-09-29 Twist Bioscience Corp Variant nucleic acid libraries for antibody optimization
EP3987019A4 (fr) 2019-06-21 2023-04-19 Twist Bioscience Corporation Assemblage de séquences d'acide nucléique basé sur des code-barres
EP3994167A4 (fr) * 2019-07-02 2023-11-01 Astute Medical, Inc. Anticorps et dosages pour ccl14
AU2020331301A1 (en) * 2019-08-09 2022-02-24 The Board Of Trustees Of The Leland Stanford Junior University Therapeutic antibodies against osteopontin
US20210102195A1 (en) * 2019-09-23 2021-04-08 Twist Bioscience Corporation Variant nucleic acid libraries for single domain antibodies
US11827709B2 (en) * 2019-12-05 2023-11-28 Seagen Inc. Anti-AVB6 antibodies and antibody-drug conjugates
CN114907468B (zh) * 2022-06-10 2023-05-23 东莞理工学院 一种仿刺参整合素多克隆抗体、抗原蛋白及其制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0341303A4 (fr) * 1987-11-19 1990-06-27 Scripps Clinic Res Anticorps monoclonal utilise contre le recepteur d'adhesion a direction rgd de cellules endotheliales.
UA58482C2 (uk) * 1994-06-08 2003-08-15 Бьорінгер Інгельхайм Інтернаціональ Гмбх Моноклональне антитіло vff-18 проти сd44v6 і його фрагменти
CN1194667A (zh) * 1995-09-01 1998-09-30 拉莫特大学应用研究及工业发展有限公司 用于癌症治疗、预防和检测的蛋白质磷酸酶2C-PP2Cα-在肿瘤细胞中表达的操作和检测方法
WO1999062933A2 (fr) 1998-06-02 1999-12-09 Affina Immuntechnik Gmbh Peptides conçus de maniere rationnelle, leur production et leur utilisation
US7163681B2 (en) * 2000-08-07 2007-01-16 Centocor, Inc. Anti-integrin antibodies, compositions, methods and uses
ATE368688T1 (de) 2000-11-08 2007-08-15 Fresenius Medical Care Affina Peptide, deren herstellung und verwendung zur bindung von immunglobulinen
US20030087250A1 (en) * 2001-03-14 2003-05-08 Millennium Pharmaceuticals, Inc. Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer
CA2478239A1 (fr) 2002-03-04 2003-09-18 Medimmune, Inc. Prevention ou traitement de cancer au moyen d'antagonistes de l'integrine alphavbeta3 combines a d'autres agents
EA011853B1 (ru) 2002-03-13 2009-06-30 Байоджен Айдек Ма Инк. АНТИТЕЛА ПРОТИВ αβ
AU2003230929A1 (en) * 2002-04-12 2003-10-27 Raven Biotechnologies, Inc. Antibodies that bind to integrin alpha-v-beta-6 and methods of use thereof
WO2004007530A2 (fr) 2002-07-17 2004-01-22 The Center For Blood Research, Inc. Proteines modifiees stabilisees dans une conformation voulue et procedes de production de celles-ci
CN1444043A (zh) * 2002-12-25 2003-09-24 帕弗瑞生物技术(北京)有限公司 一种个体化特异性免疫细胞功能测定方法
SE0301087D0 (sv) * 2003-04-14 2003-04-14 Cartela Ab New monoclonal antibody
US7429487B2 (en) 2005-07-05 2008-09-30 Epitomics, Inc. Fusion partner for production of monoclonal rabbit antibodies
AU2006332216A1 (en) 2005-12-30 2007-07-12 Merck Patent Gmbh Anti-IL-6 antibodies preventing the binding of IL-6 complexed with IL-6Ralpha to gp130
WO2009010290A2 (fr) * 2007-07-17 2009-01-22 Merck Patent Gmbh Anticorps hybrides modifiés dirigés contre l'intégrine alpha v

Also Published As

Publication number Publication date
EP2467401A2 (fr) 2012-06-27
ES2622487T3 (es) 2017-07-06
JP2013502205A (ja) 2013-01-24
WO2011020529A3 (fr) 2011-06-16
BR112012003686A2 (pt) 2016-03-29
JP5734978B2 (ja) 2015-06-17
EP2467401B1 (fr) 2017-01-18
AU2010285265A1 (en) 2012-04-05
HK1173455A1 (en) 2013-05-16
CA2771441A1 (fr) 2011-02-24
AU2010285265B2 (en) 2015-05-21
DK2467401T3 (en) 2017-03-20
US8420348B2 (en) 2013-04-16
EA201200281A1 (ru) 2012-09-28
PT2467401T (pt) 2017-04-26
SG178348A1 (en) 2012-03-29
AU2010285265A2 (en) 2012-06-07
US20130203079A1 (en) 2013-08-08
EA032728B1 (ru) 2019-07-31
CA2771441C (fr) 2016-10-11
KR101606236B1 (ko) 2016-03-24
WO2011020529A2 (fr) 2011-02-24
BR112012003686B1 (pt) 2021-09-21
CN102597001A (zh) 2012-07-18
CN102597001B (zh) 2014-07-30
WO2011020529A8 (fr) 2011-04-21
MX2012001741A (es) 2012-03-21
IL218119A0 (en) 2012-04-30
KR20120059556A (ko) 2012-06-08
US20120171699A1 (en) 2012-07-05
ZA201201990B (en) 2012-11-28
US8993261B2 (en) 2015-03-31

Similar Documents

Publication Publication Date Title
HK1173455A1 (en) Antibodies for the detection of integrin complexes in ffpe material ffpe
IL277166B (en) Methods and materials for improving gastrointestinal activity
IL244197A0 (en) Antibodies against cd100 and methods of using them
IL287311A (en) Antibodies and processes for their preparation
ZA201106983B (en) Soluble "heavy-chain only" antibodies
IL220390A (en) Nano-active material for attachment and methods for attaching it
ZA201107486B (en) Anti-tnf-x antibodies and their uses
EP2494062A4 (fr) Anticorps anti-glp-1r et leurs utilisations
IL226801B (en) Material for radomes and process for preparation
HK1209131A1 (en) Anti-alpha2 integrin antibodies and their uses -2
GB201011574D0 (en) PCBN material
IL220536A0 (en) Anti - bv8 antibodies and uses thereof
HK1168653A1 (en) A-fucosylation detection in antibodies a-
EP2507263A4 (fr) Anticorps anti-igf-ir et leurs utilisations
IL214527A0 (en) Anti-mst1r antibodies and uses thereof
GB201009976D0 (en) Material and process
EP2419440A4 (fr) Ligands peptidiques pour la clustérine et leurs utilisations
EP2612893A4 (fr) Matériau thermofluorescent et son procédé de production
GB201011579D0 (en) PCBN material
PL392328A1 (pl) 2-(Benzyloksykarbonyloamino)-6-izocyjanoheksaniany alkilowe oraz sposób ich wytwarzania
PL390642A1 (pl) Luminofor i sposób jego otrzymywania

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed