IL215195A0 - Method of treating nonalcoholic steatohepatitis with elevated doses of ursodeoxycholic acid - Google Patents

Method of treating nonalcoholic steatohepatitis with elevated doses of ursodeoxycholic acid

Info

Publication number
IL215195A0
IL215195A0 IL215195A IL21519511A IL215195A0 IL 215195 A0 IL215195 A0 IL 215195A0 IL 215195 A IL215195 A IL 215195A IL 21519511 A IL21519511 A IL 21519511A IL 215195 A0 IL215195 A0 IL 215195A0
Authority
IL
Israel
Prior art keywords
ursodeoxycholic acid
nonalcoholic steatohepatitis
treating nonalcoholic
elevated doses
doses
Prior art date
Application number
IL215195A
Other languages
English (en)
Original Assignee
Axcan Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axcan Pharma Inc filed Critical Axcan Pharma Inc
Publication of IL215195A0 publication Critical patent/IL215195A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL215195A 2009-03-17 2011-09-18 Method of treating nonalcoholic steatohepatitis with elevated doses of ursodeoxycholic acid IL215195A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16095509P 2009-03-17 2009-03-17
PCT/IB2010/000551 WO2010106420A1 (en) 2009-03-17 2010-03-16 Method of treating nonalcoholic steatohepatitis with elevated doses of ursodeoxycholic acid

Publications (1)

Publication Number Publication Date
IL215195A0 true IL215195A0 (en) 2011-12-29

Family

ID=42167374

Family Applications (1)

Application Number Title Priority Date Filing Date
IL215195A IL215195A0 (en) 2009-03-17 2011-09-18 Method of treating nonalcoholic steatohepatitis with elevated doses of ursodeoxycholic acid

Country Status (12)

Country Link
US (1) US20120071451A1 (enExample)
EP (1) EP2408457A1 (enExample)
JP (1) JP2012520866A (enExample)
KR (1) KR20120008034A (enExample)
CN (1) CN102361642A (enExample)
AU (1) AU2010224587A1 (enExample)
CA (1) CA2755708A1 (enExample)
IL (1) IL215195A0 (enExample)
MX (1) MX2011009757A (enExample)
RU (1) RU2011139643A (enExample)
WO (1) WO2010106420A1 (enExample)
ZA (1) ZA201107578B (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011140441A2 (en) 2010-05-06 2011-11-10 Children's Hospital Medical Center Methods and systems for converting precursor cells into intestinal tissues through directed differentiation
KR101401628B1 (ko) * 2012-12-24 2014-06-02 삼성제약공업주식회사 간기능 개선용 정제 및 그 제조 방법
US9814733B2 (en) * 2012-12-31 2017-11-14 A,arin Pharmaceuticals Ireland Limited Compositions comprising EPA and obeticholic acid and methods of use thereof
EP3712254A1 (en) 2014-05-28 2020-09-23 Children's Hospital Medical Center Methods and systems for converting precursor cells into gastric tissues through directed differentiation
CN110179792A (zh) * 2014-07-29 2019-08-30 深圳君圣泰生物技术有限公司 小檗碱盐、熊去氧胆酸盐、相关复方及其制备方法和应用
WO2016061464A1 (en) 2014-10-17 2016-04-21 Children's Hospital Center, D/B/A Cincinnati Children's Hospital Medical Center In vivo model of human small intetine using pluripotent stem cells and methods of making and using same
PE20180690A1 (es) 2015-04-27 2018-04-23 Intercept Pharmaceuticals Inc Composiciones de acido obeticolico y metodos de uso
US10925854B2 (en) * 2015-11-19 2021-02-23 Sinew Pharma Inc. Methods and compositions for preventing or treating fatty liver, protecting liver function or ameliorating liver diseases caused by fatty liver or other associated disorders
CA3016641A1 (en) 2016-05-05 2017-11-09 Children's Hospital Medical Center Methods for the in vitro manufacture of gastric fundus tissue and compositions related to same
KR102546194B1 (ko) 2016-11-04 2023-06-21 칠드런즈 호스피탈 메디칼 센터 간 유사 장기 조성물 및 이를 제조 및 사용하는 방법
KR102807995B1 (ko) 2016-12-05 2025-05-16 칠드런즈 호스피탈 메디칼 센터 결장 유사장기 및 이를 제조 및 사용하는 방법
JP7248586B2 (ja) 2017-04-14 2023-03-29 チルドレンズ ホスピタル メディカル センター 複数ドナー幹細胞組成物およびそれを作製する方法
US11179364B2 (en) * 2017-06-21 2021-11-23 Novartis Ag Licofligozin for the treatment of non-alcoholic steatohepatitis
WO2019074793A1 (en) 2017-10-10 2019-04-18 Children's Hospital Medical Center OESOPHAGIAN TISSUE COMPOSITIONS AND / OR ORGANOIDS AND METHODS OF MAKING SAME
KR101887561B1 (ko) * 2017-11-15 2018-09-06 주식회사 대웅제약 간염 바이러스에 의해 유발된 간 섬유화의 개선을 위한 약학 조성물
WO2019126626A1 (en) 2017-12-21 2019-06-27 Children's Hospital Medical Center Digitalized human organoids and methods of using same
CA3106634A1 (en) 2018-07-26 2020-01-30 Children's Hospital Medical Center Hepato-biliary-pancreatic tissues and methods of making same
RU2686042C1 (ru) * 2018-09-04 2019-04-23 Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования "Российская медицинская академия непрерывного профессионального образования" Министерства здравоохранения Российской Федерации (ФГБОУ ДПО РМАНПО Минздрава России) Способ лечения неалкогольной жировой болезни печени при метаболическом синдроме
US12428622B2 (en) 2018-09-12 2025-09-30 Children's Hospital Medical Center Organoid compositions for the production of hematopoietic stem cells and derivatives thereof
JP7303372B2 (ja) * 2019-07-30 2023-07-04 コバイオラブス，インコーポレーテッド 肝損傷予防、改善、または治療用組成物、および肝損傷予防、改善、または治療方法
KR102395036B1 (ko) * 2019-07-30 2022-05-09 주식회사 고바이오랩 비알코올성 지방간 질환의 예측 또는 진단용 키트, 및 진단방법
PH12022551256A1 (en) * 2020-01-28 2023-11-20 Shilpa Medicare Ltd Method for administration of ursodeoxycholic acid
EP4232045A4 (en) * 2020-10-23 2024-09-04 Shenzhen Hightide Biopharmaceutical Ltd. BERBERINE URSODEOXYCHOLATE COMPOSITIONS AND RELATED METHODS FOR THE TREATMENT OF FATTY LIVER, DIABETES AND HYPERLIPIDEMIA
CN115137732A (zh) * 2021-03-29 2022-10-04 中国科学院大连化学物理研究所 Gpr120受体激动剂及熊去氧胆酸的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6297229B1 (en) * 1994-11-14 2001-10-02 Mayo Foundation For Medical Education And Research Use of ursodeoxycholic acid to treat nonalcoholic steatohepatitis

Also Published As

Publication number Publication date
MX2011009757A (es) 2012-02-28
KR20120008034A (ko) 2012-01-25
CA2755708A1 (en) 2010-09-23
RU2011139643A (ru) 2013-04-27
JP2012520866A (ja) 2012-09-10
WO2010106420A1 (en) 2010-09-23
CN102361642A (zh) 2012-02-22
AU2010224587A1 (en) 2011-09-22
EP2408457A1 (en) 2012-01-25
ZA201107578B (en) 2013-06-26
US20120071451A1 (en) 2012-03-22

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