CA2755708A1 - Method of treating nonalcoholic steatohepatitis with elevated doses of ursodeoxycholic acid - Google Patents
Method of treating nonalcoholic steatohepatitis with elevated doses of ursodeoxycholic acid Download PDFInfo
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- CA2755708A1 CA2755708A1 CA2755708A CA2755708A CA2755708A1 CA 2755708 A1 CA2755708 A1 CA 2755708A1 CA 2755708 A CA2755708 A CA 2755708A CA 2755708 A CA2755708 A CA 2755708A CA 2755708 A1 CA2755708 A1 CA 2755708A1
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- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16095509P | 2009-03-17 | 2009-03-17 | |
| US61/160,955 | 2009-03-17 | ||
| PCT/IB2010/000551 WO2010106420A1 (en) | 2009-03-17 | 2010-03-16 | Method of treating nonalcoholic steatohepatitis with elevated doses of ursodeoxycholic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2755708A1 true CA2755708A1 (en) | 2010-09-23 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2755708A Abandoned CA2755708A1 (en) | 2009-03-17 | 2010-03-16 | Method of treating nonalcoholic steatohepatitis with elevated doses of ursodeoxycholic acid |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20120071451A1 (enExample) |
| EP (1) | EP2408457A1 (enExample) |
| JP (1) | JP2012520866A (enExample) |
| KR (1) | KR20120008034A (enExample) |
| CN (1) | CN102361642A (enExample) |
| AU (1) | AU2010224587A1 (enExample) |
| CA (1) | CA2755708A1 (enExample) |
| IL (1) | IL215195A0 (enExample) |
| MX (1) | MX2011009757A (enExample) |
| RU (1) | RU2011139643A (enExample) |
| WO (1) | WO2010106420A1 (enExample) |
| ZA (1) | ZA201107578B (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011140441A2 (en) | 2010-05-06 | 2011-11-10 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| KR101401628B1 (ko) * | 2012-12-24 | 2014-06-02 | 삼성제약공업주식회사 | 간기능 개선용 정제 및 그 제조 방법 |
| US9814733B2 (en) * | 2012-12-31 | 2017-11-14 | A,arin Pharmaceuticals Ireland Limited | Compositions comprising EPA and obeticholic acid and methods of use thereof |
| US10174289B2 (en) | 2014-05-28 | 2019-01-08 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into gastric tissues through directed differentiation |
| KR102573865B1 (ko) * | 2014-07-29 | 2023-09-05 | 센젠 하이타이드 바이오파마슈티컬 리미티드 | 베르베린 염, 우르소데옥시콜산 염 및 병용물, 이들의 제조 및 응용 방법 |
| WO2016061464A1 (en) | 2014-10-17 | 2016-04-21 | Children's Hospital Center, D/B/A Cincinnati Children's Hospital Medical Center | In vivo model of human small intetine using pluripotent stem cells and methods of making and using same |
| PE20180690A1 (es) * | 2015-04-27 | 2018-04-23 | Intercept Pharmaceuticals Inc | Composiciones de acido obeticolico y metodos de uso |
| CN107613968A (zh) * | 2015-11-19 | 2018-01-19 | 欣耀生医股份有限公司 | 预防或治疗脂肪肝的药物组合物 |
| US11066650B2 (en) | 2016-05-05 | 2021-07-20 | Children's Hospital Medical Center | Methods for the in vitro manufacture of gastric fundus tissue and compositions related to same |
| KR102546194B1 (ko) | 2016-11-04 | 2023-06-21 | 칠드런즈 호스피탈 메디칼 센터 | 간 유사 장기 조성물 및 이를 제조 및 사용하는 방법 |
| JP7068305B2 (ja) | 2016-12-05 | 2022-05-16 | チルドレンズ ホスピタル メディカル センター | 結腸オルガノイドならびにその作製方法および使用方法 |
| WO2018191673A1 (en) | 2017-04-14 | 2018-10-18 | Children's Hospital Medical Center | Multi donor stem cell compositions and methods of making same |
| CN110958878A (zh) * | 2017-06-21 | 2020-04-03 | 诺华股份有限公司 | 用于治疗非酒精性脂肪性肝炎的licofligozin |
| CN111565798B (zh) | 2017-10-10 | 2025-06-24 | 儿童医院医学中心 | 食道组织和/或类器官组合物及其制备方法 |
| KR101887561B1 (ko) * | 2017-11-15 | 2018-09-06 | 주식회사 대웅제약 | 간염 바이러스에 의해 유발된 간 섬유화의 개선을 위한 약학 조성물 |
| EP3727394A4 (en) | 2017-12-21 | 2021-09-08 | Children's Hospital Medical Center | DIGITALIZED HUMAN ORGANOIDS AND METHOD OF USING THEREOF |
| WO2020023245A1 (en) | 2018-07-26 | 2020-01-30 | Children's Hospital Medical Center | Hepato-biliary-pancreatic tissues and methods of making same |
| RU2686042C1 (ru) * | 2018-09-04 | 2019-04-23 | Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования "Российская медицинская академия непрерывного профессионального образования" Министерства здравоохранения Российской Федерации (ФГБОУ ДПО РМАНПО Минздрава России) | Способ лечения неалкогольной жировой болезни печени при метаболическом синдроме |
| CA3112026A1 (en) | 2018-09-12 | 2020-03-19 | Children's Hospital Medical Center | Organoid compositions for the production of hematopoietic stem cells and derivatives thereof |
| JP7610533B2 (ja) | 2019-05-31 | 2025-01-08 | チルドレンズ ホスピタル メディカル センター | 造血幹細胞の生成および拡大方法 |
| KR102401535B1 (ko) * | 2019-07-30 | 2022-05-24 | 주식회사 고바이오랩 | 간 손상 예방, 개선, 또는 치료용 조성물 |
| CA3148434A1 (en) * | 2019-07-30 | 2021-02-04 | Kobiolabs, Inc. | Composition and method for preventing, alleviating, or treating liver injury |
| MX2022009182A (es) * | 2020-01-28 | 2022-08-17 | Shilpa Medicare Ltd | Metodo de administracion del acido ursodeoxicolico. |
| CN116782898A (zh) * | 2020-10-23 | 2023-09-19 | 深圳君圣泰生物技术有限公司 | 小檗碱熊去氧胆酸盐的组合物及其用于治疗脂肪性肝病、糖尿病和高脂血症的方法 |
| CN115137732A (zh) * | 2021-03-29 | 2022-10-04 | 中国科学院大连化学物理研究所 | Gpr120受体激动剂及熊去氧胆酸的应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US6297229B1 (en) * | 1994-11-14 | 2001-10-02 | Mayo Foundation For Medical Education And Research | Use of ursodeoxycholic acid to treat nonalcoholic steatohepatitis |
-
2010
- 2010-03-16 MX MX2011009757A patent/MX2011009757A/es not_active Application Discontinuation
- 2010-03-16 CN CN2010800119928A patent/CN102361642A/zh active Pending
- 2010-03-16 EP EP10714958A patent/EP2408457A1/en not_active Ceased
- 2010-03-16 RU RU2011139643/15A patent/RU2011139643A/ru not_active Application Discontinuation
- 2010-03-16 AU AU2010224587A patent/AU2010224587A1/en not_active Abandoned
- 2010-03-16 WO PCT/IB2010/000551 patent/WO2010106420A1/en not_active Ceased
- 2010-03-16 KR KR1020117024296A patent/KR20120008034A/ko not_active Withdrawn
- 2010-03-16 JP JP2012500328A patent/JP2012520866A/ja active Pending
- 2010-03-16 CA CA2755708A patent/CA2755708A1/en not_active Abandoned
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2011
- 2011-08-24 US US13/217,042 patent/US20120071451A1/en not_active Abandoned
- 2011-09-18 IL IL215195A patent/IL215195A0/en unknown
- 2011-10-17 ZA ZA2011/07578A patent/ZA201107578B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2408457A1 (en) | 2012-01-25 |
| AU2010224587A1 (en) | 2011-09-22 |
| CN102361642A (zh) | 2012-02-22 |
| IL215195A0 (en) | 2011-12-29 |
| MX2011009757A (es) | 2012-02-28 |
| ZA201107578B (en) | 2013-06-26 |
| KR20120008034A (ko) | 2012-01-25 |
| RU2011139643A (ru) | 2013-04-27 |
| JP2012520866A (ja) | 2012-09-10 |
| US20120071451A1 (en) | 2012-03-22 |
| WO2010106420A1 (en) | 2010-09-23 |
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| FZDE | Discontinued |
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