IL214576B - Apolipoprotein i-a mimic peptides, preparations containing them and their uses - Google Patents
Apolipoprotein i-a mimic peptides, preparations containing them and their usesInfo
- Publication number
- IL214576B IL214576B IL214576A IL21457611A IL214576B IL 214576 B IL214576 B IL 214576B IL 214576 A IL214576 A IL 214576A IL 21457611 A IL21457611 A IL 21457611A IL 214576 B IL214576 B IL 214576B
- Authority
- IL
- Israel
- Prior art keywords
- apolipoprotein
- compositions
- same
- mimic peptides
- mimic
- Prior art date
Links
- 102000005666 Apolipoprotein A-I Human genes 0.000 title 1
- 108010059886 Apolipoprotein A-I Proteins 0.000 title 1
- 230000003278 mimic effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Marine Sciences & Fisheries (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15296609P | 2009-02-16 | 2009-02-16 | |
| US15296009P | 2009-02-16 | 2009-02-16 | |
| US15296209P | 2009-02-16 | 2009-02-16 | |
| PCT/US2010/024096 WO2010093918A1 (en) | 2009-02-16 | 2010-02-12 | Apolipoprotein a-i mimics |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL214576A0 IL214576A0 (en) | 2011-09-27 |
| IL214576B true IL214576B (en) | 2019-05-30 |
Family
ID=42562076
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL214576A IL214576B (en) | 2009-02-16 | 2011-08-10 | Apolipoprotein i-a mimic peptides, preparations containing them and their uses |
| IL240357A IL240357A (en) | 2009-02-16 | 2015-08-04 | Waiting peptides for polypropoprotein a – i, preparations containing them and their uses |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL240357A IL240357A (en) | 2009-02-16 | 2015-08-04 | Waiting peptides for polypropoprotein a – i, preparations containing them and their uses |
Country Status (26)
| Country | Link |
|---|---|
| US (4) | US8378068B2 (https=) |
| EP (2) | EP2939683B1 (https=) |
| JP (2) | JP5719783B2 (https=) |
| KR (1) | KR101688547B1 (https=) |
| CN (2) | CN104530223A (https=) |
| AU (1) | AU2010213568B2 (https=) |
| CA (2) | CA2982157A1 (https=) |
| CY (1) | CY1118809T1 (https=) |
| DK (2) | DK2939683T3 (https=) |
| ES (2) | ES2620478T3 (https=) |
| HK (1) | HK1209436A1 (https=) |
| HR (2) | HRP20150998T1 (https=) |
| HU (2) | HUE026062T2 (https=) |
| IL (2) | IL214576B (https=) |
| LT (1) | LT2939683T (https=) |
| MX (3) | MX386110B (https=) |
| NZ (1) | NZ594516A (https=) |
| PH (1) | PH12016501912A1 (https=) |
| PL (2) | PL2939683T3 (https=) |
| PT (2) | PT2396017E (https=) |
| RU (2) | RU2532222C2 (https=) |
| SG (1) | SG173624A1 (https=) |
| SI (2) | SI2939683T1 (https=) |
| SM (2) | SMT201700203T1 (https=) |
| WO (1) | WO2010093918A1 (https=) |
| ZA (1) | ZA201105997B (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2653840A1 (en) * | 2006-06-01 | 2007-12-06 | Institut De Cardiologie De Montreal | Use of a peptide/phospholipid complex acting as a reverse lipid transport agonist for treatment of valvular stenosis |
| US20120141576A1 (en) * | 2007-03-15 | 2012-06-07 | Benjamin Johnson | Treatment of Dermatologic Skin Disorders |
| US20110059549A1 (en) | 2007-05-09 | 2011-03-10 | Coleman Matthew A | Methods and systems for producing nanolipoprotein particles |
| US9688718B2 (en) | 2008-01-11 | 2017-06-27 | Lawrence Livermore National Security, Llc | Nanolipoprotein particles comprising hydrogenases and related products, methods and systems |
| LT2939683T (lt) | 2009-02-16 | 2017-03-27 | Cerenis Therapeutics Holding Sa | Apolipoproteino a-i mimetikai |
| WO2012101142A1 (en) | 2011-01-26 | 2012-08-02 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Method for assessing a subject's risk of having a cardiovascular disease. |
| EP2673296B1 (en) * | 2011-02-07 | 2018-10-24 | Cerenis Therapeutics Holding SA | Lipoprotein complexes and manufacturing and uses thereof |
| US9644038B2 (en) | 2011-12-21 | 2017-05-09 | The Regents Of The University Of California | Apolipoprotein nanodiscs with telodendrimer |
| WO2013188879A1 (en) | 2012-06-16 | 2013-12-19 | Atherotech, Inc. | Measurement of serum lipoproteins |
| US9239280B2 (en) | 2012-06-16 | 2016-01-19 | Atherotech, Inc. | Measurement of serum lipoproteins |
| WO2015173633A2 (en) | 2014-05-02 | 2015-11-19 | Cerenis Therapeutics Holding Sa | Hdl therapy markers |
| WO2016049061A1 (en) | 2014-09-22 | 2016-03-31 | Lawrence Livermore National Security, Llc | Electrochemical flow-cell for hydrogen production and nicotinamide co-factor dependent target reduction, and related methods and systems |
| WO2016154544A1 (en) | 2015-03-25 | 2016-09-29 | The Regents Of The University Of Michigan | Compositions and methods for delivery of biomacromolecule agents |
| US12226529B2 (en) | 2015-08-25 | 2025-02-18 | Lawrence Livermore National Security, Llc | Stable nanolipoprotein particles and related compositions methods and systems |
| WO2017044899A1 (en) * | 2015-09-11 | 2017-03-16 | Lawrence Livermore National Security, Llc | Synthetic apolipoproteins, and related compositions methods and systems for nanolipoprotein particles formation |
| WO2017205454A1 (en) * | 2016-05-24 | 2017-11-30 | Bryce Chackerian | Immunogens, compositions, and methods for treating dyslipidemia |
| WO2018204495A1 (en) | 2017-05-02 | 2018-11-08 | Synthetic Genomics, Inc. | Nanolipoprotein particles and related compositions methods and systems for loading rna |
| US11207422B2 (en) | 2017-05-02 | 2021-12-28 | Lawrence Livermore National Security, Llc | MOMP telonanoparticles, and related compositions, methods and systems |
| ES2984286T3 (es) * | 2017-08-10 | 2024-10-29 | Abionyx Pharma Sa | Apómeros |
| WO2019030574A1 (en) * | 2017-08-10 | 2019-02-14 | Cerenis Therapeutics Holding | Cargomers |
| IL297046A (en) | 2020-04-16 | 2022-12-01 | Abionyx Pharma Sa | Treatment of kidney disease using cer-001 |
| WO2021209808A1 (en) * | 2020-04-16 | 2021-10-21 | Abionyx Pharma Sa | Cer-001 therapy for treating kidney disease |
| KR20230004605A (ko) | 2020-04-16 | 2023-01-06 | 아비오닉스 파마 에스에이 | 지질 결합 단백질-기반 복합체를 사용하여 급성 상태를 치료하는 방법 |
| MX2023003877A (es) | 2020-10-01 | 2023-04-18 | Abionyx Pharma Sa | Composiciones que comprenden complejos basados en proteina de union a lipidos para usarse en el tratamiento de enfermedades oculares. |
| EP4259280A4 (en) * | 2020-12-11 | 2025-02-12 | The Regents Of The University Of Michigan | Compositions and methods for preventing, attenuating, and treating medical conditions with shdl nanoparticles |
| KR20240018430A (ko) | 2021-04-15 | 2024-02-13 | 아비오닉스 파마 에스에이 | 기관 보존 용액에서의 지질 결합 단백질-기반 복합체의 사용 |
| CN114940711B (zh) * | 2021-10-25 | 2023-05-12 | 中山大学 | 载脂蛋白a-i模拟肽及其应用 |
| AU2023250345A1 (en) | 2022-04-06 | 2024-11-14 | Abionyx Pharma Sa | Methods for treating eye diseases using lipid binding protein-based complexes |
| CA3247588A1 (en) | 2022-04-06 | 2023-10-12 | Abionyx Pharma Sa | METHODS FOR TREATING LEUKOCYTOSIS, ENDOTHELIAL DYSFUNCTION AND CARDITIS USING LIPID-BINDING PROTEIN COMPLEXES |
| WO2023237927A2 (en) | 2022-06-10 | 2023-12-14 | Abionyx Pharma Sa | Methods for treating hyperinflammatory conditions using lipid binding protein -based complexes |
| JP2025519606A (ja) | 2022-06-10 | 2025-06-26 | アビオニクス ファーマ エスエー | 脂質結合タンパク質に基づく複合体を使用して急性状態を処置するための方法 |
| US12060148B2 (en) | 2022-08-16 | 2024-08-13 | Honeywell International Inc. | Ground resonance detection and warning system and method |
| WO2024150064A1 (en) | 2023-01-13 | 2024-07-18 | Abionyx Pharma Sa | Lipid binding protein molecule therapy |
| WO2025093929A1 (en) | 2023-10-31 | 2025-05-08 | Abionyx Pharma Sa | Lipid binding protein molecule therapy |
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| CA2653840A1 (en) * | 2006-06-01 | 2007-12-06 | Institut De Cardiologie De Montreal | Use of a peptide/phospholipid complex acting as a reverse lipid transport agonist for treatment of valvular stenosis |
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| CA2788223A1 (en) | 2009-01-23 | 2010-07-29 | Institut De Cardiologie De Montreal | Method for the prevention and treatment of diastolic dysfunction employing an apolipoproteina1 (apoa1) mimetic peptide/phospholipid complex |
| LT2939683T (lt) | 2009-02-16 | 2017-03-27 | Cerenis Therapeutics Holding Sa | Apolipoproteino a-i mimetikai |
| CA2806606A1 (en) * | 2010-07-28 | 2012-02-02 | Institut De Cardiologie De Montreal | Pharmaceutical compositions for the treatment of left ventricular diastolic dysfunction comprising an apolipoprotein peptide/phospholipid complex |
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2010
- 2010-02-12 LT LTEP15157397.9T patent/LT2939683T/lt unknown
- 2010-02-12 SG SG2011057569A patent/SG173624A1/en unknown
- 2010-02-12 CA CA2982157A patent/CA2982157A1/en not_active Abandoned
- 2010-02-12 PT PT107418014T patent/PT2396017E/pt unknown
- 2010-02-12 ES ES15157397.9T patent/ES2620478T3/es active Active
- 2010-02-12 HR HRP20150998TT patent/HRP20150998T1/hr unknown
- 2010-02-12 PL PL15157397T patent/PL2939683T3/pl unknown
- 2010-02-12 SM SM20170203T patent/SMT201700203T1/it unknown
- 2010-02-12 JP JP2011550271A patent/JP5719783B2/ja active Active
- 2010-02-12 MX MX2016014789A patent/MX386110B/es unknown
- 2010-02-12 PL PL10741801T patent/PL2396017T3/pl unknown
- 2010-02-12 US US12/705,094 patent/US8378068B2/en active Active
- 2010-02-12 AU AU2010213568A patent/AU2010213568B2/en active Active
- 2010-02-12 DK DK15157397.9T patent/DK2939683T3/en active
- 2010-02-12 MX MX2014006888A patent/MX343654B/es unknown
- 2010-02-12 MX MX2011008599A patent/MX2011008599A/es active IP Right Grant
- 2010-02-12 WO PCT/US2010/024096 patent/WO2010093918A1/en not_active Ceased
- 2010-02-12 CN CN201410745103.0A patent/CN104530223A/zh active Pending
- 2010-02-12 CA CA2752182A patent/CA2752182C/en active Active
- 2010-02-12 RU RU2011138011/10A patent/RU2532222C2/ru not_active IP Right Cessation
- 2010-02-12 HU HUE10741801A patent/HUE026062T2/en unknown
- 2010-02-12 HU HUE15157397A patent/HUE033661T2/en unknown
- 2010-02-12 CN CN201080016764.XA patent/CN102395375B/zh active Active
- 2010-02-12 SI SI201031428A patent/SI2939683T1/sl unknown
- 2010-02-12 NZ NZ594516A patent/NZ594516A/xx not_active IP Right Cessation
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