IL193196A - The total vaccine carried yeast and the protein of fusion of the influenza virus - Google Patents
The total vaccine carried yeast and the protein of fusion of the influenza virusInfo
- Publication number
- IL193196A IL193196A IL193196A IL19319608A IL193196A IL 193196 A IL193196 A IL 193196A IL 193196 A IL193196 A IL 193196A IL 19319608 A IL19319608 A IL 19319608A IL 193196 A IL193196 A IL 193196A
- Authority
- IL
- Israel
- Prior art keywords
- vaccine
- protein
- yeast
- influenza
- anyone
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title claims 21
- 240000004808 Saccharomyces cerevisiae Species 0.000 title claims 16
- 241000712461 unidentified influenza virus Species 0.000 title claims 5
- 108010059722 Viral Fusion Proteins Proteins 0.000 title claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 13
- 108090000623 proteins and genes Proteins 0.000 claims 13
- 206010022000 influenza Diseases 0.000 claims 10
- 108020001507 fusion proteins Proteins 0.000 claims 7
- 102000037865 fusion proteins Human genes 0.000 claims 7
- 230000002163 immunogen Effects 0.000 claims 7
- 101710154606 Hemagglutinin Proteins 0.000 claims 4
- 102000005348 Neuraminidase Human genes 0.000 claims 4
- 108010006232 Neuraminidase Proteins 0.000 claims 4
- 101710093908 Outer capsid protein VP4 Proteins 0.000 claims 4
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 claims 4
- 101710176177 Protein A56 Proteins 0.000 claims 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 238000009472 formulation Methods 0.000 claims 4
- 239000000185 hemagglutinin Substances 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 239000000427 antigen Substances 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 241000235648 Pichia Species 0.000 claims 2
- 241000235070 Saccharomyces Species 0.000 claims 2
- 241000222120 Candida <Saccharomycetales> Species 0.000 claims 1
- 241000235346 Schizosaccharomyces Species 0.000 claims 1
- 230000008512 biological response Effects 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 230000003834 intracellular effect Effects 0.000 claims 1
- 230000021633 leukocyte mediated immunity Effects 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 239000003607 modifier Substances 0.000 claims 1
- 210000005253 yeast cell Anatomy 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/21—Retroviridae, e.g. equine infectious anemia virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55588—Adjuvants of undefined constitution
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16311—Influenzavirus C, i.e. influenza C virus
- C12N2760/16334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76502506P | 2006-02-02 | 2006-02-02 | |
| PCT/US2007/061572 WO2007092792A2 (en) | 2006-02-02 | 2007-02-02 | Yeast-based vaccine for inducing an immune response |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL193196A0 IL193196A0 (en) | 2011-08-01 |
| IL193196A true IL193196A (en) | 2015-01-29 |
Family
ID=38345897
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL193196A IL193196A (en) | 2006-02-02 | 2008-07-31 | The total vaccine carried yeast and the protein of fusion of the influenza virus |
| IL232518A IL232518A0 (en) | 2006-02-02 | 2014-05-08 | A yeast-based vaccine to stimulate an immune response |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL232518A IL232518A0 (en) | 2006-02-02 | 2014-05-08 | A yeast-based vaccine to stimulate an immune response |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US7736642B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP1988919A4 (cg-RX-API-DMAC7.html) |
| JP (3) | JP5198290B2 (cg-RX-API-DMAC7.html) |
| KR (2) | KR20140029551A (cg-RX-API-DMAC7.html) |
| CN (2) | CN104826102A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2007212076B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0706913A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2638815A1 (cg-RX-API-DMAC7.html) |
| IL (2) | IL193196A (cg-RX-API-DMAC7.html) |
| IN (1) | IN2014DN08830A (cg-RX-API-DMAC7.html) |
| MX (1) | MX2008009929A (cg-RX-API-DMAC7.html) |
| SG (2) | SG10201402236VA (cg-RX-API-DMAC7.html) |
| TW (2) | TW200806316A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2007092792A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7083787B2 (en) * | 2000-11-15 | 2006-08-01 | Globeimmune, Inc. | Yeast-dendritic cell vaccines and uses thereof |
| WO2004058157A2 (en) * | 2002-12-16 | 2004-07-15 | Globeimmune, Inc. | Yeast-based vaccines as immunotherapy |
| US8343502B2 (en) * | 2002-12-16 | 2013-01-01 | Globeimmune, Inc. | Yeast-based vaccines as immunotherapy |
| US20100034840A1 (en) * | 2005-07-11 | 2010-02-11 | David Apelian | Compositions and methods for eliciting an immune response to escape mutants of targeted therapies |
| US20070172503A1 (en) * | 2005-12-13 | 2007-07-26 | Mycologics,Inc. | Compositions and Methods to Elicit Immune Responses Against Pathogenic Organisms Using Yeast Based Vaccines |
| EP1988919A4 (en) * | 2006-02-02 | 2009-06-10 | Globeimmune Inc | VAKZINE ON YEAST BASE FOR TRIGGERING AN IMMUNE RESPONSE |
| GB0613977D0 (en) | 2006-02-07 | 2006-08-23 | Peptcell Ltd | Peptide sequences and compositions |
| WO2007130330A2 (en) * | 2006-05-01 | 2007-11-15 | Technovax, Inc. | Polyvalent influenza virus-like particle (vlp) compositions |
| US20100143393A1 (en) * | 2006-05-11 | 2010-06-10 | Gale Smith | Novel influenza m2 vaccines |
| DK2023952T3 (en) * | 2006-05-18 | 2015-10-19 | Epimmune Inc | Induction of immune responses to influenza virus using polypeptide and nucleic acid compositions |
| EP2121013B1 (en) * | 2007-02-02 | 2014-10-15 | Globeimmune, Inc. | Methods for producing yeast-based vaccines |
| US8501167B2 (en) * | 2007-03-19 | 2013-08-06 | Globeimmune, Inc. | Compositions and methods for targeted ablation of mutational escape of targeted therapies for cancer |
| GB0719526D0 (en) * | 2007-10-05 | 2007-11-14 | Isis Innovation | Compositions and methods |
| US20100285050A1 (en) | 2007-10-05 | 2010-11-11 | Isis Innovation Limited | Compositions and Methods |
| US20110177122A1 (en) * | 2008-09-26 | 2011-07-21 | The United States Of America, As Represented By The Secretary, Dept. Of Health & Human Services | Dna prime/activated vaccine boost immunization to influenza virus |
| EP2419126B1 (en) | 2009-04-17 | 2018-01-10 | Globeimmune, Inc. | Combination immunotherapy compositions against cancer and methods |
| JP2012527232A (ja) * | 2009-05-18 | 2012-11-08 | パナセア バイオテック リミテッド | 遺伝子組換え改変ワクシニアアンカラウイルス(mva)ベースのインフルエンザ万能ワクチン |
| CA2774326C (en) | 2009-09-14 | 2023-11-07 | Donald Bellgrau | Modulation of yeast-based immunotherapy products and responses |
| WO2012006561A2 (en) * | 2010-07-08 | 2012-01-12 | New York Medical College | Influenza virus detection and diagnosis |
| SG189236A1 (en) * | 2010-10-04 | 2013-05-31 | Massachusetts Inst Technology | Hemagglutinin polypeptides, and reagents and methods relating thereto |
| AU2011316164B2 (en) * | 2010-10-15 | 2016-01-14 | Bavarian Nordic A/S | Recombinant modified vaccinia virus Ankara (MVA) influenza vaccine |
| WO2012083302A2 (en) | 2010-12-17 | 2012-06-21 | Globeimmune, Inc. | Compositions and methods for the treatment or prevention of human adenovirus-36 infection |
| US9463237B2 (en) * | 2011-01-31 | 2016-10-11 | Baxalta Incorporated | Recombinant viral vectors and methods for inducing a heterosubtypic immune response to influenza A viruses |
| CN103476426B (zh) | 2011-02-12 | 2021-08-10 | 全球免疫股份有限公司 | 用于慢性乙型肝炎病毒感染的基于酵母的治疗剂 |
| RU2690180C2 (ru) * | 2011-03-17 | 2019-05-31 | Глоубиммьюн, Инк. | Иммунотерапевтические композиции на основе дрожжей с brachyury |
| US20140377295A1 (en) * | 2011-05-23 | 2014-12-25 | The Wistar Institute Of Anatomy And Biology | Influenza vaccines containing modified adenovirus vectors |
| SG10201605265TA (en) | 2011-06-14 | 2016-08-30 | Globeimmune Inc | Yeast-Based Compositions and Methods for the Treatment or Prevention of Hepatitis Delta Virus Infection |
| CN103732749B (zh) * | 2011-06-20 | 2017-03-29 | 高等教育联邦系统-匹兹堡大学 | 计算优化的宽反应性的h1n1流感抗原 |
| BR112014003477B1 (pt) | 2011-08-17 | 2021-11-03 | Globeimmune, Inc. | Composição imunoterapêutica de muc1 de levedura |
| PL2591798T3 (pl) | 2011-11-09 | 2015-04-30 | Werner Lubitz | Szczepionka do zastosowania w immunoterapii nowotworów |
| DE102011121069A1 (de) | 2011-12-13 | 2013-06-13 | Martin-Luther-Universität Halle-Wittenberg | Vakzinierung mittels rekombinanter Hefe durch Erzeugung einer protektiven humoralen Immunantwort gegen definierte Antigene |
| AU2013281221B2 (en) | 2012-06-26 | 2018-05-17 | Biodesix, Inc. | Mass-spectral method for selection, and de-selection, of cancer patients for treatment with immune response generating therapies |
| US9744193B2 (en) | 2012-09-06 | 2017-08-29 | Orbis Health Solutions Llc | Tumor lysate loaded particles |
| JP5954079B2 (ja) | 2012-09-25 | 2016-07-20 | ソニー株式会社 | 培養観察装置及び培養観察方法 |
| AU2013359469B2 (en) * | 2012-12-10 | 2019-05-16 | Seattle Biomedical Research Institute | Cell-free biofragment compositions and related systems, devices, and methods |
| WO2014151279A1 (en) * | 2013-03-15 | 2014-09-25 | The Trustees Of The University Of Pennsylvania | Vaccines having an antigen and interleukin-23 as an adjuvant |
| WO2014186047A1 (en) | 2013-03-19 | 2014-11-20 | Globeimmune, Inc. | Yeast-based immunotherapy for chordoma |
| TWI728239B (zh) * | 2013-03-26 | 2021-05-21 | 美商環球免疫公司 | 治療或預防人類免疫缺乏病毒感染之組合物及方法 |
| JP2014210747A (ja) * | 2013-04-19 | 2014-11-13 | アンジェスMg株式会社 | 細胞性免疫誘導能が改善された経口ワクチン |
| WO2015031778A2 (en) | 2013-08-30 | 2015-03-05 | Globeimmune, Inc. | Compositions and methods for the treatment or prevention of tuberculosis |
| EP4070818A3 (en) | 2014-01-06 | 2023-01-11 | The Trustees of the University of Pennsylvania | Pd1 and pdl1 antibodies and vaccine combinations and use of same for immunotherapy |
| EP3113759B1 (en) | 2014-03-05 | 2021-05-12 | Orbis Health Solutions LLC | Vaccine delivery systems using yeast cell wall particles |
| WO2015157639A1 (en) | 2014-04-11 | 2015-10-15 | Globeimmune, Inc. | Yeast-based immunotherapy and type i interferon sensitivity |
| CN105233302B (zh) * | 2014-07-10 | 2018-10-19 | 中国人民解放军军事医学科学院生物工程研究所 | 一种流感血凝素糖蛋白多聚物纳米颗粒的制备方法 |
| US10695417B2 (en) | 2015-01-09 | 2020-06-30 | Etubics Corporation | Human adenovirus serotype 5 vectors containing E1 and E2B deletions encoding the ebola virus glycoprotein |
| WO2016168187A1 (en) * | 2015-04-13 | 2016-10-20 | The Regents Of The University Of Michigan | Virus-like particles |
| JP6789283B2 (ja) | 2015-08-03 | 2020-11-25 | グローブイミューン,インコーポレイテッド | 改変酵母−ブラキュリー免疫療法組成物 |
| JP6956067B2 (ja) * | 2015-08-11 | 2021-10-27 | オービス ヘルス ソリューションズ エルエルシー | 細菌およびウイルスのワクチン戦略 |
| GB2552441A (en) * | 2015-10-22 | 2018-01-31 | Royal Veterinary College | Methods |
| EP3195878A1 (en) | 2016-01-22 | 2017-07-26 | Werner Lubitz | Bacterial ghosts for the treatment of cancer |
| US11154597B2 (en) | 2016-03-24 | 2021-10-26 | Nantcell, Inc. | Sequence arrangements and sequences for neoepitope presentation |
| SG11201909882SA (en) | 2017-04-24 | 2019-11-28 | Nantcell Inc | Targeted neoepitope vectors and methods therefor |
| WO2019124557A1 (ja) | 2017-12-21 | 2019-06-27 | 株式会社グリーンバイオメッド | 交差免疫抗原ワクチン及びその調製方法 |
| DE102017012109A1 (de) * | 2017-12-27 | 2019-06-27 | Martin-Luther-Universität Halle-Wittenberg | Optimiertes Wirts-/Vektorsystem zur Erzeugung protektiver mono- und multivalenter subunit-Vakzine auf Basis der Hefe Kluyveromyces lactis |
| WO2019222073A1 (en) | 2018-05-15 | 2019-11-21 | Globeimmune, Inc. | Lysates of recombinant yeast for inducing cellular immune responses |
| EP3851120A4 (en) * | 2018-09-11 | 2022-04-27 | Shanghai Public Health Clinical Center | Immunogen for broad-spectrum influenza vaccine and application thereof |
| US20210290708A1 (en) | 2018-09-21 | 2021-09-23 | Nantcell, Inc. | Methods and compositions for modulating myeloid-derived suppressor cells |
| CN114269374A (zh) * | 2019-05-21 | 2022-04-01 | 艾斯佩罗疫苗公司 | 基于酵母的口服疫苗接种 |
| JP2023515355A (ja) * | 2020-02-11 | 2023-04-13 | サイトナス セラピューティクス,インク. | 高速ワクチンプラットフォーム |
| US12285480B2 (en) | 2020-03-11 | 2025-04-29 | Nantcell, Inc. | Method of inducing immunity against SARS-CoV-2 using spike and nucleocapsid-ETSD immunogens delivered by RNA and replication-defective adenoviruses |
| US11857620B2 (en) | 2020-03-11 | 2024-01-02 | Immunitybio, Inc. | Method of inducing immunity against SARS-CoV-2 using spike (s) and nucleocapsid (N)-ETSD immunogens delivered by a replication-defective adenovirus |
| US20210284716A1 (en) | 2020-03-11 | 2021-09-16 | Immunitybio, Inc. | ACE2-Fc Trap |
| CA3170359A1 (en) | 2020-04-14 | 2021-10-21 | Nantcell, Inc. | Yeast lysate covid-19 vaccine |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5413914A (en) | 1993-07-07 | 1995-05-09 | The Regents Of The University Of Colorado | Yeast assay to identify inhibitors of dibasic amino acid processing endoproteases |
| US5830463A (en) * | 1993-07-07 | 1998-11-03 | University Technology Corporation | Yeast-based delivery vehicles |
| CN1149888A (zh) * | 1994-01-11 | 1997-05-14 | 福拉姆斯大学生物技术研究所 | 流感疫苗 |
| US5691189A (en) * | 1994-01-19 | 1997-11-25 | Bristol-Myers Squibb Company | Saccharomyces cerevisiae expressing M2 protein of influenza A virus |
| US6696251B1 (en) * | 1996-05-31 | 2004-02-24 | Board Of Trustees Of The University Of Illinois | Yeast cell surface display of proteins and uses thereof |
| US20020044948A1 (en) * | 2000-03-15 | 2002-04-18 | Samir Khleif | Methods and compositions for co-stimulation of immunological responses to peptide antigens |
| KR100877019B1 (ko) * | 2000-06-23 | 2009-01-07 | 와이어쓰 홀딩스 코포레이션 | 야생형 및 키메릭 인플루엔자 바이러스성입자(브이엘피)의 조립 |
| US7083787B2 (en) * | 2000-11-15 | 2006-08-01 | Globeimmune, Inc. | Yeast-dendritic cell vaccines and uses thereof |
| US20030008000A1 (en) * | 2001-03-08 | 2003-01-09 | Wong Jonathan P. | DNA vaccine using liposome-encapsulated plasmid DNA encoding for hemagglutinin protein of influenza virus |
| US20030202982A1 (en) * | 2001-08-15 | 2003-10-30 | Birkett Ashley J. | Influenza immunogen and vaccine |
| WO2004058157A2 (en) * | 2002-12-16 | 2004-07-15 | Globeimmune, Inc. | Yeast-based vaccines as immunotherapy |
| US7439042B2 (en) | 2002-12-16 | 2008-10-21 | Globeimmune, Inc. | Yeast-based therapeutic for chronic hepatitis C infection |
| US8592197B2 (en) * | 2003-07-11 | 2013-11-26 | Novavax, Inc. | Functional influenza virus-like particles (VLPs) |
| CA2566355C (en) * | 2004-05-18 | 2014-04-15 | Vical Incorporated | Influenza virus vaccine composition and methods of use |
| ATE536175T1 (de) * | 2004-09-17 | 2011-12-15 | Univ Massachusetts | Zusammensetzungen und ihre verwendungen bei lysosomalen enzymstörungen |
| EP1988919A4 (en) * | 2006-02-02 | 2009-06-10 | Globeimmune Inc | VAKZINE ON YEAST BASE FOR TRIGGERING AN IMMUNE RESPONSE |
-
2007
- 2007-02-02 EP EP07717549A patent/EP1988919A4/en not_active Withdrawn
- 2007-02-02 TW TW096103976A patent/TW200806316A/zh unknown
- 2007-02-02 AU AU2007212076A patent/AU2007212076B2/en not_active Ceased
- 2007-02-02 SG SG10201402236VA patent/SG10201402236VA/en unknown
- 2007-02-02 IN IN8830DEN2014 patent/IN2014DN08830A/en unknown
- 2007-02-02 US US11/670,902 patent/US7736642B2/en not_active Expired - Fee Related
- 2007-02-02 TW TW102144486A patent/TW201412329A/zh unknown
- 2007-02-02 EP EP11180828.3A patent/EP2468296A3/en not_active Withdrawn
- 2007-02-02 CA CA002638815A patent/CA2638815A1/en not_active Withdrawn
- 2007-02-02 MX MX2008009929A patent/MX2008009929A/es active IP Right Grant
- 2007-02-02 JP JP2008553534A patent/JP5198290B2/ja not_active Expired - Fee Related
- 2007-02-02 WO PCT/US2007/061572 patent/WO2007092792A2/en not_active Ceased
- 2007-02-02 SG SG201100779-6A patent/SG169375A1/en unknown
- 2007-02-02 KR KR1020147004408A patent/KR20140029551A/ko not_active Withdrawn
- 2007-02-02 CN CN201510122553.9A patent/CN104826102A/zh not_active Withdrawn
- 2007-02-02 KR KR20087020923A patent/KR101492524B1/ko not_active Ceased
- 2007-02-02 CN CN200780009861.4A patent/CN101405026B/zh not_active Expired - Fee Related
- 2007-02-02 BR BRPI0706913-8A patent/BRPI0706913A2/pt not_active Application Discontinuation
-
2008
- 2008-07-31 IL IL193196A patent/IL193196A/en active IP Right Review Request
-
2010
- 2010-04-16 US US12/762,221 patent/US20100196411A1/en not_active Abandoned
-
2012
- 2012-11-29 JP JP2012260860A patent/JP2013075899A/ja active Pending
-
2014
- 2014-05-08 IL IL232518A patent/IL232518A0/en unknown
- 2014-11-13 JP JP2014230982A patent/JP2015038147A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| KR20080089671A (ko) | 2008-10-07 |
| JP2013075899A (ja) | 2013-04-25 |
| EP2468296A3 (en) | 2013-12-04 |
| US20080003239A1 (en) | 2008-01-03 |
| CN101405026A (zh) | 2009-04-08 |
| JP2015038147A (ja) | 2015-02-26 |
| IL232518A0 (en) | 2014-06-30 |
| JP2009528987A (ja) | 2009-08-13 |
| US7736642B2 (en) | 2010-06-15 |
| KR20140029551A (ko) | 2014-03-10 |
| IL193196A0 (en) | 2011-08-01 |
| TW201412329A (zh) | 2014-04-01 |
| IN2014DN08830A (cg-RX-API-DMAC7.html) | 2015-07-10 |
| WO2007092792A2 (en) | 2007-08-16 |
| EP1988919A2 (en) | 2008-11-12 |
| MX2008009929A (es) | 2008-10-01 |
| CA2638815A1 (en) | 2007-08-16 |
| CN101405026B (zh) | 2015-04-22 |
| AU2007212076A1 (en) | 2007-08-16 |
| JP5198290B2 (ja) | 2013-05-15 |
| KR101492524B1 (ko) | 2015-02-12 |
| EP2468296A2 (en) | 2012-06-27 |
| TW200806316A (en) | 2008-02-01 |
| SG10201402236VA (en) | 2014-08-28 |
| EP1988919A4 (en) | 2009-06-10 |
| SG169375A1 (en) | 2011-03-30 |
| WO2007092792A3 (en) | 2008-02-28 |
| AU2007212076B2 (en) | 2012-10-18 |
| US20100196411A1 (en) | 2010-08-05 |
| CN104826102A (zh) | 2015-08-12 |
| BRPI0706913A2 (pt) | 2011-04-12 |
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| ME | Application for patent revocation filed | ||
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Free format text: THE OWNER OF PATENT NO. 193196 HAS REQUESTED ITS CANCELLATION. THE REQUEST IS PUBLISHED FOR OPPOSITION BY INTERESTED PARTIES. |